Patents Assigned to Bioalvo-Servicos, Investigacao e Desenvolvirmento em Biotecnologis S.A.
  • SCREENING METHOD FOR COMPOUNDS THAT REDUCE ER STRESS
    Publication number: 20100215641
    Abstract: The present invention relates to a cell comprising an Endoplasmic Reticulum (ER) stress element operably linked to a reporter element and an exogenous gene encoding a protein that induces ER stress. Methods of screening using the modified cell, constructs used in the modified cell, the candidate agents identified by the screen and uses thereof are also part of the invention.
    Type: Application
    Filed: June 6, 2008
    Publication date: August 26, 2010
    Applicant: Bioalvo-Servicos, Investigacao e Desenvolvirmento em Biotecnologis S.A.
    Inventors: Christophe Francois Aime Roca, Jose Manuel Bernardo Sousa, Marta Isabel Heitor Cerejo, Alexandra Maria Barros Dos Santos, Catia Santana Reverendo Rodrigues, Ricardo Filipe Antunes Pinheiro, Patricia Ramalhete Mendes da Silva Calado, Sukalyan Chatterjee, Helena Margarida Moreira de Oliveira Vieira