Patents Assigned to BIOAVAILABILITY SYSTEM, LLC
  • Anti-first-pass effect compounds
    Patent number: 7514572
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for inhibiting the first pass effect.
    Type: Grant
    Filed: October 25, 2007
    Date of Patent: April 7, 2009
    Assignee: Bioavailability Systems, LLC
    Inventor: James W. Harris
  • Anti-first-pass effect compounds
    Patent number: 7378534
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for inhibiting the first pass effect.
    Type: Grant
    Filed: August 29, 2005
    Date of Patent: May 27, 2008
    Assignee: Bioavailability Systems, LLC.
    Inventor: James W. Harris
  • ANTI-FIRST-PASS EFFECT COMPOUNDS
    Publication number: 20080103194
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for inhibiting the first pass effect.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 1, 2008
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James HARRIS
  • ANTI-FIRST-PASS EFFECT COMPOUNDS
    Publication number: 20080039520
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for their preparation and for inhibiting the first pass effect.
    Type: Application
    Filed: May 11, 2007
    Publication date: February 14, 2008
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James Harris
  • ANTI-FIRST-PASS EFFECT COMPOUNDS
    Publication number: 20070244188
    Abstract: Compositions, methods, etc. for addressing the first-pass effect.
    Type: Application
    Filed: April 4, 2007
    Publication date: October 18, 2007
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James HARRIS
  • Anti-first-pass effect compounds
    Publication number: 20060135598
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for inhibiting the first pass effect.
    Type: Application
    Filed: August 29, 2005
    Publication date: June 22, 2006
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James Harris
  • Anti-first-pass effect compounds
    Publication number: 20050214366
    Abstract: Compositions, methods, etc. for addressing the first-pass effect.
    Type: Application
    Filed: March 16, 2005
    Publication date: September 29, 2005
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James Harris
  • Anti-first-pass effect compounds
    Publication number: 20050171191
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for their preparation and for inhibiting the first pass effect.
    Type: Application
    Filed: August 26, 2004
    Publication date: August 4, 2005
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James Harris
  • Anti-first-pass effect compounds
    Publication number: 20040214847
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for inhibiting the first pass effect.
    Type: Application
    Filed: August 26, 2003
    Publication date: October 28, 2004
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James W. Harris
  • Synthesis of spiro esters, spiro ortho carbonates, and intermediates
    Patent number: 6734313
    Abstract: Ortho esters and ortho carbonates can be produced by alkylating esters and carbonates with, for example, the hexafluorophosphate salt of a trialkyl oxonium ion. The spiro species are useful intermediates in the synthesis of complex organic molecules. Synthetic pathways for the production of medically active compounds incorporates spiro ortho esters. Anti-first-pass effect materials are produced in high yield utilizing a synthetic strategy incorporating cyclic ortho ester intermediates.
    Type: Grant
    Filed: May 9, 2003
    Date of Patent: May 11, 2004
    Assignee: Bioavailability Systems, LLC
    Inventors: Robert Seemayer, Jack Liang
  • Pharmaceutical compositions
    Publication number: 20040058982
    Abstract: Compositions, methods, etc. for addressing the first-pass effect.
    Type: Application
    Filed: April 25, 2003
    Publication date: March 25, 2004
    Applicant: BIOAVAILABILITY SYSTEM, LLC
    Inventor: James W. Harris
  • Synthesis of spiro esters, spiro ortho carbonates, and intermediates
    Publication number: 20040002611
    Abstract: Ortho esters and ortho carbonates can be produced by alkylating esters and carbonates with, for example, the hexafluorophosphate salt of a trialkyl oxonium ion. The spiro species are useful intermediates in the synthesis of complex organic molecules. Synthetic pathways for the production of medically active compounds incorporates spiro ortho esters. Anti-first-pass effect materials are produced in high yield utilizing a synthetic strategy incorporating cyclic ortho ester intermediates.
    Type: Application
    Filed: May 9, 2003
    Publication date: January 1, 2004
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventors: Robert Seemayer, Jack Liang
  • Anti-first-pass effect compounds
    Publication number: 20030235632
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided.
    Type: Application
    Filed: September 9, 2002
    Publication date: December 25, 2003
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James W. Harris
  • Anti-first-pass effect compounds
    Patent number: 6660766
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for inhibiting the first pass effect.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: December 9, 2003
    Assignee: Bioavailability Systems, LLC
    Inventor: James W. Harris
  • Synthesis of spiro ortho esters, spiro ortho carbonates, and intermediates
    Patent number: 6613918
    Abstract: Ortho esters and ortho carbonates can be produced by alkylating esters and carbonates with, for example, the hexafluorophosphate salt of a trialkyl oxonium ion. The spiro species are useful intermediates in the synthesis of complex organic molecules. Synthetic pathways for the production of medically active compounds incorporates spiro ortho esters. Anti-first-pass effect materials are produced in high yield utilizing a synthetic strategy incorporating cyclic ortho ester intermediates.
    Type: Grant
    Filed: October 22, 2001
    Date of Patent: September 2, 2003
    Assignee: Bioavailability Systems, LLC
    Inventors: Robert Seemayer, Jack Liang
  • Method for simplified shipping of clinical specimens and optional direct analysis
    Patent number: 6458322
    Abstract: A method for shipping clinical specimens lawfully, safely, cheaply, and easily without regard to some or all of the laws, rules, and regulations regarding samples that may contain infectious and/or etiologic agents. Optional method of direct analysis of shipped samples.
    Type: Grant
    Filed: September 8, 2000
    Date of Patent: October 1, 2002
    Assignee: Bioavailability Systems, LLC
    Inventor: James W. Harris
  • Method for simplified shipping of clinical specimens and optional direct analysis
    Publication number: 20020136663
    Abstract: A method for shipping clinical specimens lawfully, safely, cheaply, and easily without regard to some or all of the laws, rules, and regulations regarding samples that may contain infectious and/or etiologic agents. Optional method of direct analysis of shipped samples.
    Type: Application
    Filed: May 21, 2002
    Publication date: September 26, 2002
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James W. Harris
  • Anti-first-pass effect compounds
    Publication number: 20020019544
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for inhibiting the first pass effect.
    Type: Application
    Filed: July 30, 2001
    Publication date: February 14, 2002
    Applicant: BIOAVAILABILITY SYSTEMS, LLC
    Inventor: James W. Harris
  • Anti-first-pass effect compounds
    Patent number: 6162479
    Abstract: Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for inhibiting the first pass effect.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: December 19, 2000
    Assignee: Bioavailability Systems, LLC
    Inventor: James W. Harris
  • Anti-first-pass effect compounds
    Patent number: 6124477
    Abstract: The present inventor has discovered chemical compounds which inhibit the first-pass effect of orally administered drugs in humans; that phototoxic low molecular weight furocoumarins and certain ether-substituted furocoumarins that are naturally present in citrus extracts, juices, byproducts, etc. may be removed therefrom or reduced in concentration without destroying the first-pass effect inhibiting compounds therein, and a method for preparing citrus-based compositions using only FDA or USP acceptable reagents.
    Type: Grant
    Filed: December 30, 1997
    Date of Patent: September 26, 2000
    Assignee: Bioavailability Systems, LLC
    Inventor: James W. Harris