Abstract: The present invention relates to a novel protein transduction domain (PTD), which is a peptide having an amino acid sequence represented by SEQ ID NO: 1, and a use thereof. When the peptide represented by SEQ ID NO: 1 of the present invention is used as a PTD, biological molecules (target materials) such as proteins, peptides, DNA and the like can be easily introduced into cells in a high yield.

Abstract: Disclosed are a composition for inhibiting hyperlipidemia and obesity through suppression of intestinal cholesterol absorption. An IgY-type antibody derived from yolk to NPC1L1 (Niemann-Pick C1-Like1), contained, as an active ingredient, in the composition of the present invention is linked to NPC1L1 (Niemann-Pick C1-Like1) that is a cholesterol transport protein in the intestines, thus interfering with binding between cholesterol and the transport protein to completely block absorption of cholesterol in the body and thereby prevent hyperlipidemia and obesity.