Abstract: The invention relates to a new economical and simple process, using a new intermediate compound, for the production of 3′-substituted 7-amino-3-propenyl-4-cephem-carboxylic acid derivatives of formula
wherein R is hydrogen, a negative charge or a silyl protecting group, Ro is hydrogen or methoxy, R1 is hydrogen or a silyl protecting group and X is the radical of a nucleophile, and their acid addition salts.
Type:
Grant
Filed:
October 8, 1997
Date of Patent:
January 2, 2001
Assignee:
Biochemie Gesellschaft
Inventors:
Johannes Ludescher, Hubert Sturm, Josef Wieser
Abstract: The invention relates to a new economical and simple process, using a new intermediate compound, for the production of 3'-substituted 7-amino-3-propenyl-4-cephem-carboxylic acid derivatives of formula ##STR1## wherein R is hydrogen, a negative charge or a silyl protecting group, R.sub.o is hydrogen or methoxy, R.sub.1 is hydrogen or a silyl protecting group and X is the radical of a nucleophile, and their acid addition salts.
Type:
Grant
Filed:
May 5, 1995
Date of Patent:
November 11, 1997
Assignee:
Biochemie Gesellschaft
Inventors:
Johannes Ludescher, Hubert Sturm, Josef Wieser