Patents Assigned to Biochemie S.A.
  • Macrolides
    Patent number: 6703372
    Abstract: Azithromycin in the form of a stable monohydrate and processes for the preparation of azithromycin in the form of an, e.g. stable, monohydrate.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: March 9, 2004
    Assignee: Biochemie S.A.
    Inventors: Victor Centellas, Rafael Garcia, Marta Poch, José Diago, Johannes Ludescher, Immaculada Bosch
  • Macrolide intermediates in the preparation of clarithromycin
    Patent number: 6599886
    Abstract: The present invention relates to a process for the production of clarithromycin from an aqueous medium in anhydrous form and in the form of a hydrate.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: July 29, 2003
    Assignee: Biochemie S.A.
    Inventors: Victor Centellas, José Diago
  • Erthromycin a oxime solvates
    Patent number: 6504017
    Abstract: Erythromycin A oxime in the form of a hemihydrate.
    Type: Grant
    Filed: January 4, 2000
    Date of Patent: January 7, 2003
    Assignee: Biochemie S.A.
    Inventors: Immaculada Bosch, Victor Centellas, José Diago
  • Macrolide production
    Patent number: 6420537
    Abstract: A process for the production of azithromycins by methylation of the nitrogen atom in position 9 of the ring structure in 9-deoxo-9a-aza-9a-homoerythromycins in the presence of formaldehyde and in the presence of a reducing agent in non-halogenated solvent; and azithromycin which is free from halogenated organic solvent in a stable anhydrous form; or in the form of a solvate with non-halogenated solvent with the exception of water.
    Type: Grant
    Filed: November 7, 2000
    Date of Patent: July 16, 2002
    Assignee: Biochemie S.A.
    Inventors: Immaculada Bosch, Victor Centellas, José Diago