Abstract: An example device for repairing a tissue is described herein. The device can include a flexible carrier layer, and a support member including a plurality of micro-protrusions extending therefrom. The support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the tissue, and the micro-protrusions can be configured to mechanically interface with the tissue.
Type:
Grant
Filed:
November 5, 2021
Date of Patent:
March 5, 2024
Assignees:
BioCircuit Technologies, Inc., Virginia Commonwealth University
Inventors:
Jonathan Isaacs, Isaac Perry Clements, Andrew Willsie, James David Ross, Alex Weidenbach
Abstract: A neural interfacing device is disclosed. The neural interfacing device includes a microneedle electrode. The microneedle electrode includes a body having a void formed therein and a plurality of microneedles. The void surrounds the plurality of microneedles, and the plurality of microneedles are bent outward with respect to the body to form a three-dimensional microneedle electrode. Additionally, each of the plurality of microneedles is sized and shaped to penetrate a nerve epineurium.
Type:
Grant
Filed:
March 29, 2021
Date of Patent:
December 12, 2023
Assignee:
BioCircuit Technologies, Inc. Georgia Tech Research Corporation
Inventors:
Robert J. Butera, Yogi A. Patel, James D. Ross, Swaminathan Rajaraman, Isaac Clements
Abstract: Systems, devices, and methods for interfacing with biological tissue are described herein. An example electrode patch as described herein includes a flexible substrate and an electrode array arranged on the flexible substrate. The electrode array includes a plurality of electrodes, where each of the plurality of electrodes is formed of a hydrogel. Additionally, each of the plurality of electrodes defines a raised geometry. Additionally, an example system includes the electrode patch, which is configured to interface with a subject's skin, and an electronics module operably coupled to the electrode array.
Type:
Grant
Filed:
November 4, 2019
Date of Patent:
March 28, 2023
Assignee:
BioCircuit Technologies, Inc.
Inventors:
Isaac Perry Clements, Anna Harrison, Edgar Brown, Amanda Preyer, James David Ross, Andrew Willsie, Maximilian Sonntag
Abstract: An example device for repairing a tissue is described herein. The device can include a flexible carrier layer, and a support member including a plurality of micro-protrusions extending therefrom. The support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the tissue, and the micro-protrusions can be configured to mechanically interface with the tissue.
Type:
Grant
Filed:
May 3, 2021
Date of Patent:
November 9, 2021
Assignees:
BioCircuit Technologies, Inc., Virginia Commonwealth University
Inventors:
Jonathan Isaacs, Isaac Perry Clements, Andrew Willsie, James David Ross, Alex Weidenbach
Abstract: An example device for repairing a nerve is described herein. The device can include a flexible carrier layer made of a biologic material, and a metallic support member including a plurality of micro-protrusions extending therefrom. The metallic support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the nerve, and the micro-protrusions can be configured to attach to a superficial tissue of the nerve.
Type:
Grant
Filed:
September 6, 2017
Date of Patent:
May 4, 2021
Assignees:
BioCircuit Technologies, Inc., Virginia Commonwealth University
Inventors:
Isaac Perry Clements, Andrew Willsie, James David Ross, Alex Weidenbach, Jonathan Isaacs
Abstract: A neural interfacing device is disclosed. The neural interfacing device may include at least one microneedle electrode. The microneedle electrode may have one or more microneedles. The one or more microneedles may be shaped and positioned such that when the neural interfacing device is applied to a nerve, the one or more microneedles penetrate a nerve epineurium without any portion of the microneedle electrode penetrating any nerve axon beyond a depth of 500 micrometers.
Type:
Grant
Filed:
February 2, 2015
Date of Patent:
March 30, 2021
Assignees:
BIOCIRCUIT TECHNOLOGIES, INC., GEORGIA TECH RESEARCH CORPORATION
Inventors:
Robert J. Butera, Yogi A. Patel, James D. Ross, Swaminathan Rajaraman, Isaac Clements