Abstract: The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including a taxane or a taxane derivative. The application also describes methods for treating subjects with breast cancer by screening them for the likelihood of the effectiveness of treating the cancer with a therapy including a taxane or a taxane derivative and administering the therapy in subjects when it is found that a taxane or a taxane derivative is likely to be effective.
Type:
Grant
Filed:
November 30, 2012
Date of Patent:
November 10, 2015
Assignees:
The University of Utah Research Foundation, British Columbia Cancer Agency Branch, Washington University, The University of North Carolina at Chapel Hill, Bioclassifier, LLC
Inventors:
Charles M. Perou, Philip S. Bernard, Torsten O. Nielsen, Matthew J. Ellis, Joel S. Parker, Miguel Martin, Eva Carrasco, Rosalia Caballero