Patents Assigned to Biocodex
  • Patent number: 11872257
    Abstract: The present invention relates to Saccharomyces boulardii yeast cells, for use in the prevention or treatment of mood disorders, in a person.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: January 16, 2024
    Assignee: BIOCODEX
    Inventors: Emmanuelle Simon O'Brien, Marc Verleye, Marie-Emmanuelle Le Guern
  • Publication number: 20230277611
    Abstract: A pharmaceutical composition for promoting osteoblastogenesis, in particular a yeast cell derived product for use for promoting osteoblastogenesis in an individual. The yeast cell-derived product may be derived from yeast cells of the genus Saccharomyces and from yeast cells of the species Saccharomyces boulardii.
    Type: Application
    Filed: September 2, 2021
    Publication date: September 7, 2023
    Applicant: BIOCODEX
    Inventors: Marie-Emmanuelle LE GUERN, Marc VERLEYE
  • Patent number: 11141440
    Abstract: The present invention relates to a pharmaceutical oral formulation for use in the administration of at least two bacteria derived from fecal microbiota to mammals for the treatment and/or prevention of dysbiosis and associated pathologies. The pharmaceutical oral formulation is encapsulated mixture of at least two bacteria derived from fecal microbiota wherein the capsules are coated in a pH responsive polymer composition comprising: a. 50-70% poly(methyl acrylate-co-methyl methacrylate-co-methacrylic acid) 7:3:1 by weight of dry polymer, b. 10-30% poly(methacrylic acid-co-ethyl acrylate) 1:1 by weight of dry polymer, c. at least one fatty acid mono-, di- or tri-glyceride ester, or mixtures thereof, d. at least one plasticizer, e. at least one non-ionic emulsifier. The pharmaceutical oral formulation is especially designed to be delivered principally in the ileum and colon and to maintain the sample bacterial viability and diversity.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: October 12, 2021
    Assignees: MAAT PHARMA, BIOCODEX
    Inventors: Carole Schwintner, Marianne Robin, Jean-François Dubuisson, Hervé Affagard, Cédric Michenet, Amandine Bardy
  • Patent number: 10696647
    Abstract: The present invention relates to a compound of the following formula (I): or a pharmaceutically acceptable salt thereof, for use in the prevention or treatment of obsessions and/or compulsions in an individual.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: June 30, 2020
    Assignee: BIOCODEX
    Inventors: Marc Verleye, Marie-Emmanuelle Le Guern
  • Patent number: 10675266
    Abstract: The present invention relates to a compound of the following formula (I): or a pharmaceutically acceptable salt thereof, for use in the prevention or treatment of autism spectrum disorders (ASD).
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: June 9, 2020
    Assignee: BIOCODEX
    Inventors: Bernard Hublot, Rene Levy, Marie-Emmanuelle Le Guern
  • Patent number: 10525092
    Abstract: The present invention relates to a dietary supplement or pharmaceutical composition, comprising lyophylized Saccharomyces boulardii as an active ingredient and as sole probiotic, optionally in association with a pharmaceutically acceptable vehicle, wherein the composition is in a closed vial a having a first airtight compartment comprising lyophilized S. boulardii powder, and a second compartment comprising a solution, wherein the first and second compartment can be brought in airtight communication with one another to yield a suspension of S. boulardii to be administered to an individual upon opening of the vial.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: January 7, 2020
    Assignee: BIOCODEX
    Inventors: Jean-Marie Lefevre, Gilles Renaud, Marie-Emmanuelle Le Guern
  • Patent number: 9872858
    Abstract: The present invention relates to a compound of the following formula (I): or a pharmaceutically acceptable salt thereof, to be used in the prevention or treatment of light-induced damage and/or a degeneration of the retina in a patient.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: January 23, 2018
    Assignee: BIOCODEX
    Inventors: Marc Verleye, Philippe Girard, Marie-Emmanuelle Le Guern
  • Patent number: 8927600
    Abstract: The present invention relates to a compound of the following formula (I): or a pharmaceutically acceptable salt thereof, for use in the prevention or treatment of peripheral neuropathies.
    Type: Grant
    Filed: March 18, 2010
    Date of Patent: January 6, 2015
    Assignee: Biocodex
    Inventors: Marie-Emmanuelle Le Guern, Marc Verleye, Jean-Marie Gillardin, Bernard Hublot
  • Publication number: 20140031539
    Abstract: The present invention relates to certain purines, which act as topoisomerase II catalytic inhibitors. These compounds are useful in combination with topoisomerase II poisons, such as anthracyclines and epipodophyllotoxins, in the treatment of proliferative conditions (e.g., cancer). These compounds are useful in the treatment of tissue damage associated with extravasation of a topoisomerase II poison, such as an anthracycline or an epipodophyllotoxin.
    Type: Application
    Filed: July 3, 2013
    Publication date: January 30, 2014
    Applicant: Biocodex, Inc
    Inventors: Lars Hollund JENSEN, Maxwell SEHESTED
  • Patent number: 8598221
    Abstract: The present invention relates to a pharmaceutical composition comprising as active substances: at least one compound of the following general formula (I): and at least one inhibitor of type 2 cyclooxygenase (COX-2), notably for use in the prevention or treatment of pain.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: December 3, 2013
    Assignee: Biocodex
    Inventors: Philippe Girard, Marie-Emmanuelle Le Guern, Jean-Marie Gillardin, Bernard Hublot
  • Patent number: 8575211
    Abstract: The present invention relates to a pharmaceutical composition comprising as active substances: at least one compound of the following general formula (I): and at least one compound of the following general formula (V): especially for its use in the prevention or treatment of pain.
    Type: Grant
    Filed: October 28, 2009
    Date of Patent: November 5, 2013
    Assignee: Biocodex
    Inventors: Philippe Girard, Marie-Emmanuelle Le Guern, Laurence Berthon-Cedille, Jean-Marie Gillardin, Bernard Hublot
  • Patent number: 8420644
    Abstract: The present invention relates to the use of at least one compound of formula (I) below: or at least one of the pharmaceutically acceptable salts thereof, for the preparation of a medicament intended for the prevention or for the treatment of cerebral edemas.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: April 16, 2013
    Assignee: Biocodex
    Inventors: Marie-Emmanuelle Le Guern, Philippe Girard, Jean-Marie Gillardin, Laurence Berthon-Cedille, Bernard Hublot
  • Patent number: 8338410
    Abstract: This invention relates to the use of at least one compound of the following formula (I): or its pharmaceutically acceptable salts, for the preparation of a medicinal compound having neuroprotective activity intended to prevent or treat neurone deteriorations.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: December 25, 2012
    Assignee: Biocodex
    Inventors: Marc Verleye, Marie-Emmanuelle Le Guern, Philippe Girard, Jean-Marie Gillardin, Laurence Berthon-Cedille, Bernard Hublot
  • Patent number: 8093381
    Abstract: The invention relates to a method of preparation of fluoroquinolones of formula (I) from compounds of formula (II): in which R1, R2, R3, R4, R5, R6, R7, and X are as defined in Claim 1.
    Type: Grant
    Filed: May 22, 2008
    Date of Patent: January 10, 2012
    Assignee: Biocodex
    Inventors: Laurence Berthon-Cedille, Marie-Emmanuelle Leguern, Gilles Renaud, Francis Tombret
  • Publication number: 20100298437
    Abstract: The invention relates to the use of L-citrulline (I) or of one of its pharmaceutically acceptable salts in the preparation of a drug for the treatment of states or undernutrition as linked to a lowering of protein synthesis within the framework of pathologies which do not result from an intestinal insufficiency.
    Type: Application
    Filed: August 29, 2007
    Publication date: November 25, 2010
    Applicants: UNIVERSITE RENE DESCARTES-PARIS 5, BIOCODEX
    Inventors: Christophe Moinard, Marion Jourdan, Stephane Walrand, Luc Cynober
  • Patent number: 7799328
    Abstract: The present invention relates to a method of treating or preventing weight loss of patients with inflammatory bowel diseases comprising administering to said patients an effective amount of Saccharomyces boulardii.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: September 21, 2010
    Assignee: Biocodex
    Inventors: Bernard Hublot, Herve Groux, Rene Levy, Marie-Emmanuelle Le Guern, Paul Bernasconi
  • Patent number: 7750169
    Abstract: The invention relates to a process for the preparation of stiripentol particles having a defined particle size distribution.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: July 6, 2010
    Assignee: Biocodex
    Inventors: Bernard Hublot, Laurence Berthon-Cedille, Marie-Emmanuelle Leguern, Gilles Renaud
  • Patent number: 7569565
    Abstract: The present invention relates to the use of at least one compound of formula (I) below: or of its pharmaceutically acceptable salts, in the preparation of a medicament for the prevention or treatment of cerebral oedemas.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: August 4, 2009
    Assignee: Biocodex
    Inventors: Marie-Emmanuelle Le Guern, Philippe Girard, Jean-Marie Gillardin, Laurence Berthon-Cedille, Bernard Hublot
  • Publication number: 20060247315
    Abstract: The present invention relates to the use of L-citrulline (I) for the preparation of a medicament intended for the treatment of pathologies linked to an intestinal insufficiency.
    Type: Application
    Filed: June 30, 2006
    Publication date: November 2, 2006
    Applicants: BIOCODEX, UNIVERSITE RENE DESCARTES PARIS 5
    Inventors: Sylwia Osowska-Vincent, Christophe Moinard, Luc Cynober, Marie-Emmanuelle Le Guern, Bernard Hublot, Paul Bernasconi
  • Patent number: 5665352
    Abstract: Process for reducing the extent of Cryptosporidium diarrhoeas, which comprises administering to a patient in need thereof a therapeutically effective amount of yeasts of the Saccharomyces boulardii species. The yeasts are freeze-dried living yeasts. The yeasts are provided in the form of unit doses containing 0.050 to 3.0 g of yeasts.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: September 9, 1997
    Assignee: Laboratoires Biocodex
    Inventors: Henri Blehaut, Bernard Hublot