Patents Assigned to Biocodex
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Patent number: 11872257Abstract: The present invention relates to Saccharomyces boulardii yeast cells, for use in the prevention or treatment of mood disorders, in a person.Type: GrantFiled: August 10, 2018Date of Patent: January 16, 2024Assignee: BIOCODEXInventors: Emmanuelle Simon O'Brien, Marc Verleye, Marie-Emmanuelle Le Guern
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Publication number: 20230277611Abstract: A pharmaceutical composition for promoting osteoblastogenesis, in particular a yeast cell derived product for use for promoting osteoblastogenesis in an individual. The yeast cell-derived product may be derived from yeast cells of the genus Saccharomyces and from yeast cells of the species Saccharomyces boulardii.Type: ApplicationFiled: September 2, 2021Publication date: September 7, 2023Applicant: BIOCODEXInventors: Marie-Emmanuelle LE GUERN, Marc VERLEYE
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Patent number: 11141440Abstract: The present invention relates to a pharmaceutical oral formulation for use in the administration of at least two bacteria derived from fecal microbiota to mammals for the treatment and/or prevention of dysbiosis and associated pathologies. The pharmaceutical oral formulation is encapsulated mixture of at least two bacteria derived from fecal microbiota wherein the capsules are coated in a pH responsive polymer composition comprising: a. 50-70% poly(methyl acrylate-co-methyl methacrylate-co-methacrylic acid) 7:3:1 by weight of dry polymer, b. 10-30% poly(methacrylic acid-co-ethyl acrylate) 1:1 by weight of dry polymer, c. at least one fatty acid mono-, di- or tri-glyceride ester, or mixtures thereof, d. at least one plasticizer, e. at least one non-ionic emulsifier. The pharmaceutical oral formulation is especially designed to be delivered principally in the ileum and colon and to maintain the sample bacterial viability and diversity.Type: GrantFiled: November 16, 2018Date of Patent: October 12, 2021Assignees: MAAT PHARMA, BIOCODEXInventors: Carole Schwintner, Marianne Robin, Jean-François Dubuisson, Hervé Affagard, Cédric Michenet, Amandine Bardy
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Patent number: 10696647Abstract: The present invention relates to a compound of the following formula (I): or a pharmaceutically acceptable salt thereof, for use in the prevention or treatment of obsessions and/or compulsions in an individual.Type: GrantFiled: November 20, 2014Date of Patent: June 30, 2020Assignee: BIOCODEXInventors: Marc Verleye, Marie-Emmanuelle Le Guern
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Patent number: 10675266Abstract: The present invention relates to a compound of the following formula (I): or a pharmaceutically acceptable salt thereof, for use in the prevention or treatment of autism spectrum disorders (ASD).Type: GrantFiled: July 23, 2018Date of Patent: June 9, 2020Assignee: BIOCODEXInventors: Bernard Hublot, Rene Levy, Marie-Emmanuelle Le Guern
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Patent number: 10525092Abstract: The present invention relates to a dietary supplement or pharmaceutical composition, comprising lyophylized Saccharomyces boulardii as an active ingredient and as sole probiotic, optionally in association with a pharmaceutically acceptable vehicle, wherein the composition is in a closed vial a having a first airtight compartment comprising lyophilized S. boulardii powder, and a second compartment comprising a solution, wherein the first and second compartment can be brought in airtight communication with one another to yield a suspension of S. boulardii to be administered to an individual upon opening of the vial.Type: GrantFiled: June 11, 2015Date of Patent: January 7, 2020Assignee: BIOCODEXInventors: Jean-Marie Lefevre, Gilles Renaud, Marie-Emmanuelle Le Guern
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Patent number: 9872858Abstract: The present invention relates to a compound of the following formula (I): or a pharmaceutically acceptable salt thereof, to be used in the prevention or treatment of light-induced damage and/or a degeneration of the retina in a patient.Type: GrantFiled: January 28, 2015Date of Patent: January 23, 2018Assignee: BIOCODEXInventors: Marc Verleye, Philippe Girard, Marie-Emmanuelle Le Guern
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Patent number: 8927600Abstract: The present invention relates to a compound of the following formula (I): or a pharmaceutically acceptable salt thereof, for use in the prevention or treatment of peripheral neuropathies.Type: GrantFiled: March 18, 2010Date of Patent: January 6, 2015Assignee: BiocodexInventors: Marie-Emmanuelle Le Guern, Marc Verleye, Jean-Marie Gillardin, Bernard Hublot
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Patent number: 8598221Abstract: The present invention relates to a pharmaceutical composition comprising as active substances: at least one compound of the following general formula (I): and at least one inhibitor of type 2 cyclooxygenase (COX-2), notably for use in the prevention or treatment of pain.Type: GrantFiled: December 3, 2010Date of Patent: December 3, 2013Assignee: BiocodexInventors: Philippe Girard, Marie-Emmanuelle Le Guern, Jean-Marie Gillardin, Bernard Hublot
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Patent number: 8575211Abstract: The present invention relates to a pharmaceutical composition comprising as active substances: at least one compound of the following general formula (I): and at least one compound of the following general formula (V): especially for its use in the prevention or treatment of pain.Type: GrantFiled: October 28, 2009Date of Patent: November 5, 2013Assignee: BiocodexInventors: Philippe Girard, Marie-Emmanuelle Le Guern, Laurence Berthon-Cedille, Jean-Marie Gillardin, Bernard Hublot
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Patent number: 8420644Abstract: The present invention relates to the use of at least one compound of formula (I) below: or at least one of the pharmaceutically acceptable salts thereof, for the preparation of a medicament intended for the prevention or for the treatment of cerebral edemas.Type: GrantFiled: June 5, 2006Date of Patent: April 16, 2013Assignee: BiocodexInventors: Marie-Emmanuelle Le Guern, Philippe Girard, Jean-Marie Gillardin, Laurence Berthon-Cedille, Bernard Hublot
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Patent number: 8338410Abstract: This invention relates to the use of at least one compound of the following formula (I): or its pharmaceutically acceptable salts, for the preparation of a medicinal compound having neuroprotective activity intended to prevent or treat neurone deteriorations.Type: GrantFiled: July 18, 2006Date of Patent: December 25, 2012Assignee: BiocodexInventors: Marc Verleye, Marie-Emmanuelle Le Guern, Philippe Girard, Jean-Marie Gillardin, Laurence Berthon-Cedille, Bernard Hublot
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Patent number: 8093381Abstract: The invention relates to a method of preparation of fluoroquinolones of formula (I) from compounds of formula (II): in which R1, R2, R3, R4, R5, R6, R7, and X are as defined in Claim 1.Type: GrantFiled: May 22, 2008Date of Patent: January 10, 2012Assignee: BiocodexInventors: Laurence Berthon-Cedille, Marie-Emmanuelle Leguern, Gilles Renaud, Francis Tombret
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Publication number: 20100298437Abstract: The invention relates to the use of L-citrulline (I) or of one of its pharmaceutically acceptable salts in the preparation of a drug for the treatment of states or undernutrition as linked to a lowering of protein synthesis within the framework of pathologies which do not result from an intestinal insufficiency.Type: ApplicationFiled: August 29, 2007Publication date: November 25, 2010Applicants: UNIVERSITE RENE DESCARTES-PARIS 5, BIOCODEXInventors: Christophe Moinard, Marion Jourdan, Stephane Walrand, Luc Cynober
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Patent number: 7799328Abstract: The present invention relates to a method of treating or preventing weight loss of patients with inflammatory bowel diseases comprising administering to said patients an effective amount of Saccharomyces boulardii.Type: GrantFiled: December 23, 2004Date of Patent: September 21, 2010Assignee: BiocodexInventors: Bernard Hublot, Herve Groux, Rene Levy, Marie-Emmanuelle Le Guern, Paul Bernasconi
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Patent number: 7750169Abstract: The invention relates to a process for the preparation of stiripentol particles having a defined particle size distribution.Type: GrantFiled: January 22, 2009Date of Patent: July 6, 2010Assignee: BiocodexInventors: Bernard Hublot, Laurence Berthon-Cedille, Marie-Emmanuelle Leguern, Gilles Renaud
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Patent number: 7569565Abstract: The present invention relates to the use of at least one compound of formula (I) below: or of its pharmaceutically acceptable salts, in the preparation of a medicament for the prevention or treatment of cerebral oedemas.Type: GrantFiled: July 18, 2006Date of Patent: August 4, 2009Assignee: BiocodexInventors: Marie-Emmanuelle Le Guern, Philippe Girard, Jean-Marie Gillardin, Laurence Berthon-Cedille, Bernard Hublot
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Publication number: 20060247315Abstract: The present invention relates to the use of L-citrulline (I) for the preparation of a medicament intended for the treatment of pathologies linked to an intestinal insufficiency.Type: ApplicationFiled: June 30, 2006Publication date: November 2, 2006Applicants: BIOCODEX, UNIVERSITE RENE DESCARTES PARIS 5Inventors: Sylwia Osowska-Vincent, Christophe Moinard, Luc Cynober, Marie-Emmanuelle Le Guern, Bernard Hublot, Paul Bernasconi