Abstract: A method forming a coated implant is described. The implant comprises a surface which is first coated with a primer and subsequently with a biocompatible polymer capable of forming a covalent bond to the primer. The polymer coating is then crosslinked. The invention also relates to implants, in particular, stents, coated with such a coating.
Type:
Application
Filed:
July 16, 2007
Publication date:
December 24, 2009
Applicant:
BIOCOMPATIBLES UK LIMITED Chapman House
Inventors:
Sean Willis, Vincent James O'Byrne, Samantha Ryan
Abstract: The present invention relates to a method of monitoring live cells, comprising the sequential steps of: (i) contacting the cells with self-assembled constructs associated with an imaging agent at t=0; (ii) incubating the cells for a period of time t1; (iii) imaging at least a sample of the live cells by means of the said imaging agent after time t1; wherein in step (i), at least some of the constructs are taken up into the cells; and wherein the constructs comprise an amphiphilic block copolymer having a hydrophilic and hydrophobic block.
Type:
Application
Filed:
April 21, 2009
Publication date:
November 19, 2009
Applicant:
BIOCOMPATIBLES UK LIMITED, Chapman House