Patents Assigned to BioControl Systems, Inc.
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Patent number: 11420209Abstract: A variable spacing PCR amp tube rack can include a plurality of rotors and a plurality of carriages engaged with the rotors so that rotation of the rotors causes translation of the carriages with respect to one another. The rack can include a blade assembly that allows an operator to separate sets of coupled PCR amp tubes from one another. The rack can be designed to accommodate 0.1 ml PCR amp tubes and adjust their spacing from 4.5 mm to 9.0 mm.Type: GrantFiled: August 21, 2017Date of Patent: August 23, 2022Assignee: BIOCONTROL SYSTEMS, INC.Inventor: Joseph Berry
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Patent number: 10684232Abstract: Methods and apparatus for evaluating the quality of an environment or process by measuring light emitted from a bioluminescent sample containing ATP, ADP, or alkaline phosphatase. The apparatus comprises a sample collection and analysis system used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber. The system includes an instrument having a photon detection assembly for use with the sample testing device and one or more probe assemblies that optically cooperate with the instrument. The instrument includes a dark chamber with a reflective interior surface which may be concave or preferably spherical, and a photon detection sensor such as a multi-pixel photon counter sensor. A substantially transparent portion of the probe assembly, and liquid contained therein, focus bioluminescence toward the photon detection sensor.Type: GrantFiled: August 4, 2016Date of Patent: June 16, 2020Assignee: BIOCONTROL SYSTEMS, INC.Inventors: Marc Warren Gordon, Jon Keith Perrin, Alexander Michael Diener, David Oscar Iverson, Kyle Stuart Johnson, Garet Glenn Nenninger, John Russell Murkowski, Kristin Marie Will, Chad Austin Brinckerhoff, Phillip T. Feldsine, Tim Allen Kelly
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Patent number: 9446406Abstract: Methods and apparatus for evaluating the quality of an environment or process by measuring light emitted from a bioluminescent sample containing ATP, ADP, or alkaline phosphatase. The apparatus comprises a sample collection and analysis system used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber. The system includes an instrument having a photon detection assembly for use with the sample testing device and one or more probe assemblies that optically cooperate with the instrument. The instrument includes a dark chamber with a reflective interior surface which may be concave or preferably spherical, and a photon detection sensor such as a multi-pixel photon counter sensor. A substantially transparent portion of the probe assembly, and liquid contained therein, focus bioluminescence toward the photon detection sensor.Type: GrantFiled: October 4, 2012Date of Patent: September 20, 2016Assignee: BioControl Systems, Inc.Inventors: Marc Warren Gordon, Jon Keith Perrin, Alexander Michael Diener, David Oscar Iverson, Kyle Stuart Johnson, Garet Glenn Nenninger, John Russell Murkowski, Kristin Marie Will, Chad Austin Brinckerhoff, Phillip T. Feldsine, Tim Allen Kelly
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Patent number: 9274032Abstract: Method for handling microparticles in such a manner, that at least two treatment steps are performed for microparticles in the same vessel without moving the particles to another vessel. There are organs in the device for changing the solution without having to move the microparticles to another vessel.Type: GrantFiled: April 29, 2013Date of Patent: March 1, 2016Assignee: BioControl Systems, Inc.Inventors: Matti Korpela, Kenneth Rundt
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Patent number: 9012201Abstract: A biological component enrichment unit for the isolation, purification and/or determination of a biological component using particles (3) and/or another solid phase, which enrichment unit comprises at least one sample container (1, 15, 26, 32, 39) for the realization of the biological sample method. The enrichment unit comprises a lead-through structure (5), such as a bushing (21, 27) made up of one or several parts or a cover having one or several openings (25, 36). The lead-through structure and one or several sample containers can be brought into connection with one another so that, when the lead-through structure is placed on top of the sample container, a functional unit is formed for the realization of the biological method, such as for the binding of the component, the growing, isolation, purification, enrichment of the bacteria or cell or for another similar method.Type: GrantFiled: December 4, 2006Date of Patent: April 21, 2015Assignee: BioControl Systems, Inc.Inventors: Matti Korpela, Tytti Miettinen, Tuija Tenhunen, Teemu Korpimäki, Pekka Mattsson, Mika Tuomola
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Publication number: 20140004548Abstract: Methods and apparatus for evaluating the quality of an environment or process by measuring light emitted from a bioluminescent sample containing ATP, ADP, or alkaline phosphatase. The apparatus comprises a sample collection and analysis system used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber. The system includes an instrument having a photon detection assembly for use with the sample testing device and one or more probe assemblies that optically cooperate with the instrument. The instrument includes a dark chamber with a reflective interior surface which may be concave or preferably spherical, and a photon detection sensor such as a multi-pixel photon counter sensor. A substantially transparent portion of the probe assembly, and liquid contained therein, focus bioluminescence toward the photon detection sensor.Type: ApplicationFiled: October 4, 2012Publication date: January 2, 2014Applicant: BIOCONTROL SYSTEMS, INC.Inventors: Marc Warren Gordon, Jon Keith Perrin, Alexander Michael Diener, David Oscar Iverson, Kyle Stuart Johnson, Garet Glenn Nenninger, John Russell Murkowski, Kristin Marie Will, Chad Austin Brinckerhoff, Phillip T. Feldsine, Tim Allen Kelly
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Publication number: 20130309145Abstract: Method for handling microparticles in such a manner, that at least two treatment steps are performed for microparticles in the same vessel without moving the particles to another vessel. There are organs in the device for changing the solution without having to move the microparticles to another vessel.Type: ApplicationFiled: April 29, 2013Publication date: November 21, 2013Applicant: BioControl Systems, Inc.Inventor: BioControl Systems, Inc.
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Patent number: 8430247Abstract: Method for handling microparticles in such a manner, that at least two treatment steps are performed for microparticles in the same vessel without moving the particles to another vessel. There are organs in the device for changing the solution without having to move the microparticles to another vessel.Type: GrantFiled: November 18, 2011Date of Patent: April 30, 2013Assignee: BioControl Systems, Inc.Inventors: Matti Korpela, Kenneth Rundt
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Patent number: 8247187Abstract: The present invention relates generally to methods for detecting and identifying microorganisms and, more particularly, to methods for detecting microorganisms in a sample by incubating the sample at two temperatures to facilitate increased detection of the organism.Type: GrantFiled: August 14, 2007Date of Patent: August 21, 2012Assignee: BioControl Systems, Inc.Inventors: Markus Jucker, Philip T. Feldsine, Andrew Lienau
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Patent number: 8247204Abstract: Magnetic enrichment method, wherein the desired biological component is collected from a solution, which component is thereafter enriched in a liquid in such a manner that by means of the micro particles attached to the magnet or attached by means of at least one magnet at least one biological component is collected in a closed reactor vessel. Thereafter at least one biological component is enriched in such a manner that the desired component is released to the solution. The reactor unit is a closed vessel, wherein the prevailing conditions are controllable. The shape and the location of the magnet unit in the reactor unit are adjusted in a preferable manner to collect the desired biological component.Type: GrantFiled: October 20, 2004Date of Patent: August 21, 2012Assignee: BioControl Systems, Inc.Inventors: Matti Korpela, Kenneth Rundt
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Publication number: 20120128550Abstract: Method for handling microparticles in such a manner, that at least two treatment steps are performed for microparticles in the same vessel without moving the particles to another vessel. There are organs in the device for changing the solution without having to move the microparticles to another vessel.Type: ApplicationFiled: November 18, 2011Publication date: May 24, 2012Applicant: BIOCONTROL SYSTEMS, INC.Inventors: Matti KORPELA, Kenneth RUNDT
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Patent number: 8084271Abstract: Method for handling microparticles in such a manner, that at least two treatment steps are performed for microparticles in the same vessel without moving the particles to another vessel. There are organs in the device for changing the solution without having to move the microparticles to another vessel.Type: GrantFiled: October 20, 2004Date of Patent: December 27, 2011Assignee: BioControl Systems, Inc.Inventors: Matti Korpela, Kenneth Rundt
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Patent number: 7622046Abstract: A magnetic transfer method for sorting, collecting, transferring or dosing microparticles (22) or magnetic particles either in the same liquid (23) or from one liquid (23a) into another (23b) by using a magnetic field. The transfer device (10) comprises a magnet (13) placed inside a protective coating (21), and the collection or dozing is accomplished by changing the magnetic field of the magnet (13). The changing of the magnetic field is effected by using a ferromagnetic body, such as a plate or tube (12), comprised in the transfer device, in such manner that, when micro-particles are to be collected, the magnet is partially or completely outside the ferromagnetic body and, when the particles are to be released or dozed, the magnet is partially or completely inside or behind the ferromagnetic body.Type: GrantFiled: October 20, 2003Date of Patent: November 24, 2009Assignee: BioControl Systems, Inc.Inventors: Kenneth Rundt, Matti Korpela
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Patent number: 7560246Abstract: The present invention relates generally to compositions and methods for detecting target microorganisms in a sample. In particular, the present invention relates to compositions comprising a conditionally detectable maker and an enzyme substrate that provides detection of the target microorganism as well as methods of use thereof. With the invention disclosed herein, a widely applicable approach is revealed which utilizes a presumptive indicator for the target microorganism and non-target microorganisms capable of growth and detection in a medium followed by a confirmation indicator, which is substantially only reacted upon by the non-target microorganisms.Type: GrantFiled: August 27, 2001Date of Patent: July 14, 2009Assignee: BioControl Systems, Inc.Inventor: David E Townsend
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Patent number: 7544961Abstract: Methods and apparatus for evaluating the quality of a sample of a product, an ingredient, an environment or process by measuring multiple parameters thereof, including light emitted from a reacting sample containing ATP, ADP, alkaline phosphatase or other parameters such as pH, temperature, conductivity, reduction potential, dissolved gases, specific ions, and microbiological count. The apparatus comprises an integrated sample testing device used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber. The apparatus also comprises an instrument having a photon detection assembly for use with the sample testing device. The instrument can also comprise one or more sensing probes and a communication port to facilitate data collection, transfer and analysis.Type: GrantFiled: June 9, 2008Date of Patent: June 9, 2009Assignee: BioControl Systems, Inc.Inventors: Philip T. Feldsine, Tim A. Kelly, Jim Christensen, Joseph B. Di Carlo, Mark Andersen, Anita Kressner
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Patent number: 7399984Abstract: Methods and apparatus for evaluating the quality of a sample of a product, an ingredient, an environment or process by measuring multiple parameters thereof, including light emitted from a reacting sample containing ATP, ADP, alkaline phosphatase or other parameters such as pH, temperature, conductivity, reduction potential, dissolved gases, specific ions, and microbiological count. The apparatus comprises an integrated sample testing device used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber. The apparatus also comprises an instrument having a photon detection assembly for use with the sample testing device. The instrument can also comprise one or more sensing probes and a communication port to facilitate data collection, transfer and analysis.Type: GrantFiled: February 14, 2006Date of Patent: July 15, 2008Assignee: Biocontrol Systems Inc.Inventors: Philip T. Feldsine, Tim A. Kelly, Jim Christensen, Joseph B. Di Carlo, Mark Andersen, Anita Kressner
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Publication number: 20080070262Abstract: The present invention relates generally to methods for detecting and identifying microorganisms and, more particularly, to methods for detecting microorganisms in a sample by incubating the sample at two temperatures to facilitate increased detection of the organism.Type: ApplicationFiled: August 14, 2007Publication date: March 20, 2008Applicant: BIOCONTROL SYSTEMS, INC.Inventors: Markus Jucker, Philip Feldsine, Andrew Lienau
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Publication number: 20070065894Abstract: Methods for the detection and/or quantification of a biological material in a sample. The method includes the steps of liquefying the sample (if necessary) and pouring the liquefied sample into the incubation vessel. The incubation vessel has a generally flat horizontal surface and the surface is divided into at least one incubation site. Each incubation site is adapted to hold an aliquot of liquid and is sized and shaped, and formed of a suitable material, to hold the aliquot within the well by surface tension. Any excess liquid from the liquefied sample is poured from the surface of the incubation vessel. The method then involves incubating that incubation vessel until the presence or absence of the biological material is determined. The presence of air bubbles can be dramatically reduced by the presence of a surface acting agent in the liquid sample deposited on the device surface.Type: ApplicationFiled: September 21, 2006Publication date: March 22, 2007Applicant: Biocontrol Systems, Inc.Inventors: Andrew Croteau, Mark Pierson, David Townsend, Ali Naqui
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Patent number: 7122338Abstract: Methods for the detection and/or quantification of a biological material in a sample. The method includes the steps of liquefying the sample (if necessary) and pouring the liquefied sample into the incubation vessel. The incubation vessel has a generally flat horizontal surface and the surface is divided into at least one incubation site. Each incubation site is adapted to hold an aliquot of liquid and is sized and shaped, and formed of a suitable material, to hold the aliquot within the well by surface tension. Any excess liquid from the liquefied sample is poured from the surface of the incubation vessel. The method then involves incubating that incubation vessel until the presence or absence of the biological material is determined. The presence of air bubbles can be dramatically reduced by the presence of a surface acting agent in the liquid sample deposited on the device surface.Type: GrantFiled: January 21, 2003Date of Patent: October 17, 2006Assignee: Biocontrol Systems, Inc.Inventors: Andrew J. Crouteau, Mark W. Pierson, David E. Townsend, Ali Naqui
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Publication number: 20060139631Abstract: Methods and apparatus for evaluating the quality of a sample of a product, an ingredient, an environment or process by measuring multiple parameters thereof, including light emitted from a reacting sample containing ATP, ADP, alkaline phosphatase or other parameters such as pH, temperature, conductivity, reduction potential, dissolved gases, specific ions, and microbiological count. The apparatus comprises an integrated sample testing device used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber. The apparatus also comprises an instrument having a photon detection assembly for use with the sample testing device. The instrument can also comprise one or more sensing probes and a communication port to facilitate data collection, transfer and analysis.Type: ApplicationFiled: February 14, 2006Publication date: June 29, 2006Applicant: BIOCONTROL SYSTEMS INC.Inventors: Philip Feldsine, Tim Kelly, Jim Christensen, Joseph Di Carlo, Mark Andersen, Anita Kressner