Patents Assigned to Biocore Co., Ltd.
  • Patent number: 11473079
    Abstract: The present invention relates to a method for prenatal diagnosis using digital PCR, and more particularly to a method for providing information for diagnosis of chromosomal aneuploidy in a fetus, comprising: (a) extracting DNAs from pregnant woman's blood; (b) classifying the DNAs according to size to obtain DNAs having a size of 1,000 bp or less; (c) performing digital PCR using the obtained DNAs of step (b), for a control gene located on a chromosome not associated with chromosomal aneuploidy and a target gene located on a chromosome associated with chromosomal aneuploidy; (d) calculating a ratio of a quantitative digital PCR value of the target gene to a quantitative digital PCR value of the control gene; and (e) determining that when the ratio calculated in step (d) is 0.70-1.14, a chromosome number of the fetus is normal.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: October 18, 2022
    Assignee: BIOCORE CO., LTD.
    Inventors: Seung Yong Hwang, Moon Ju Oh, Seung Jun Kim, Jong Pil Youn, Ji Hoon Kim, Seung Yong Lee, Jeong Jin Ahn, Joon Soo Park, Hyo Jung Choi
  • Patent number: 7179600
    Abstract: The present invention discloses a method for analyzing a HCV genotype by extracting RNA from plasma and serum, performing C-type hepatitis virus (HCV) RT-PCR and then making them react on an oligonucleotide chip. The present invention also provides a method for simply and exactly examining the analysis of the HCV genotype for four people on one slide.
    Type: Grant
    Filed: April 10, 2002
    Date of Patent: February 20, 2007
    Assignee: Biocore Co., Ltd.
    Inventors: Young-Suk Park, Jae-Chan Park, Eun-Ha Kim