Abstract: An apparatus and method analyzes a metabolic profile in a biological sample. The apparatus includes an input unit for inputting the drugs and/or metabolites to be screened; a controlling unit for determining a parameter set for metabolites preparation and for mass spectrometry analysis depending on the input of the kind of metabolites to be screened; a treatment unit for preparing the metabolites to be screened depending on the determined parameter set; a mass spectrometer for performing mass spectrometry analysis on prepared metabolites depending on the parameter set; a database for storing results of analyzing and parameter sets for metabolite preparation and for mass spectrometry analyses; and an evaluation unit for evaluating the results of mass spectrometry by use of reference results stored in the database to output an analysis of the metabolites profile.
Type:
Application
Filed:
June 29, 2006
Publication date:
January 4, 2007
Applicant:
BIOCRATES LIFE SCIENCES GMBH
Inventors:
Steven Ramsay, Wolfgang Stoeggl, Klaus Weinberger, Armin Graber, Wolfgang Guggenbichler
Abstract: A device, in particular a sample preparation device for the quantitative analysis of a drug and/or metabolite profile in a biological sample, which includes an insert for such a device being impregnated with at least one internal standard, to the internal standard itself, and to a kit comprising the device. Further, the invention also relates to an apparatus containing the device, and to a method for the quantitative analysis of a drug and/or metabolite profile in a biological sample employing the device.
Type:
Application
Filed:
June 29, 2006
Publication date:
January 4, 2007
Applicant:
BIOCRATES LIFE SCIENCES GMBH
Inventors:
Steven Ramsay, Wolfgang Guggenbichler, Klaus Weinberger, Armin Graber, Wolfgang Stoeggl