Abstract: The invention pertains to a disposable cartridge suitable for use in detecting the presence of analytes in fluid samples. The cartridge is designed to provide “lab on a chip” capabilities and comprises a plurality of sample storage reservoirs and analytical compartments/channels. A valve system based on valve disks aids in securely transferring samples from storage reservoirs to analytical channels and detectors with minimal use of common channels, which reduces risk of cross-contamination.
Type:
Application
Filed:
March 9, 2012
Publication date:
January 2, 2014
Applicant:
BIODETECTION INSTRUMENTS, LLC
Inventors:
Xiaoli Su, Steve Charles Green, Robert Calvin Goforth, Qian Sun, James Randall Andress, Katherine L. Hall, Chien V. Nguyen
Abstract: The multichannel capillary biosensor system includes a selecting valve system for selection of the sample or a reagent. The selecting valve system is connected to a second valve system accommodating a sensing channel and a first bypass channel. The second valve system is connected to a directing valve system having at least two positions, with a first position being connected to a second bypass channel and a second position being connected to a detector for detecting the analyte. The device has a pump connected at one end to the second bypass channel and the detector and at a second end to a waste vessel. The device also has a control system for controlling the device. The analyte can be selected from the group of microorganisms, macromolecules, and small molecules.
Type:
Grant
Filed:
July 24, 2008
Date of Patent:
October 1, 2013
Assignees:
The Board of Trustees of the University of Arkansas, BioDetection Instruments, LLC
Inventors:
Xiao-Li Su, Zungzhong Ye, Qian Sun, Yanbin Li