Patents Assigned to BIO DOT, Inc.
  • Patent number: 6576295
    Abstract: A method and apparatus for dispensing precise quantities of reagents is disclosed including a positive displacement syringe pump in series with a dispenser, such as an aerosol dispenser or solenoid valve dispenser. The pump is controlled by a stepper motor or the like to provide an incremental quantity or continuous flow of reagent to the dispenser. The pump and dispenser are operated in cooperation with one another such that the quantity and/or flow rate of liquid dispensed by the dispenser can be precisely metered substantially independently of the particular operating parameters of said dispenser to attain a desired flow rate, droplet size or mist quality, droplet frequency and/or droplet velocity.
    Type: Grant
    Filed: April 5, 1999
    Date of Patent: June 10, 2003
    Assignee: Bio Dot, Inc.
    Inventor: Thomas C. Tisone
  • Patent number: 6537505
    Abstract: A reagent dispensing valve particularly adapted for dispensing precise microfluidic quantities of fluids. The valve includes a valve portion and a solenoid actuator that are in fluid isolation from one another. The valve portion includes a plunger and seat combination and the actuator is substantially decoupled from the fluid path through the valve. The fluid path through the valve is substantially non-tortuous, thereby minimizing localized fluid pressure drops, and hence undesirable gaseous bubble precipitation within the fluid. The valve is also configured to substantially prevent bubble accumulation. The valve can further include a bubble trap for trapping and removing bubbles.
    Type: Grant
    Filed: January 28, 1999
    Date of Patent: March 25, 2003
    Assignee: BIO DOT, Inc.
    Inventors: Edward V. LaBudde, Anthony D. Wilson
  • Patent number: 5916524
    Abstract: A method and apparatus for dispensing precise quantities of reagents is disclosed including a positive displacement syringe pump in series with a dispenser, such as an aerosol dispenser or solenoid valve dispenser. The pump is controlled by a stepper motor or the like to provide an incremental quantity or continuous flow of reagent to the dispenser. The pump and dispenser are operated in cooperation with one another such that the quantity and/or flow rate of liquid dispensed by the dispenser can be precisely metered substantially independently of the particular operating parameters of said dispenser to attain a desired flow rate, droplet size or mist quality, droplet frequency and/or droplet velocity.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: June 29, 1999
    Assignee: Bio-Dot, Inc.
    Inventor: Thomas C. Tisone
  • Patent number: 5743960
    Abstract: A reagent dispensing apparatus is provided including a positive displacement syringe pump in series with a solenoid valve dispenser. The pump is controlled by a stepper motor or the like to provide an incremental quantity or continuous flow of reagent to the solenoid valve dispenser. The solenoid valve is opened and closed in at a predetermined frequency and duty cycle to dispense droplets of reagent onto a target substrate at the metered flow rate.
    Type: Grant
    Filed: July 26, 1996
    Date of Patent: April 28, 1998
    Assignee: Bio-Dot, Inc.
    Inventor: Thomas C. Tisone
  • Patent number: 5741554
    Abstract: A method for dispensing precise quantities of reagents is disclosed including the steps of providing positive displacement syringe pump in series with a dispenser, such as a solenoid valve dispenser. The pump is controlled by a stepper motor or the like to provide an incremental quantity or continuous flow of reagent to the dispenser. The dispenser is operated in accordance with predetermined parameters to dispense droplets of reagent onto a target substrate at the metered flow rate.
    Type: Grant
    Filed: July 26, 1996
    Date of Patent: April 21, 1998
    Assignee: Bio Dot, Inc.
    Inventor: Thomas C. Tisone
  • Patent number: 5738728
    Abstract: A reagent dispensing apparatus is provided including a positive displacement syringe pump in series with an air brush dispenser. The pump is controlled by a stepper motor or the like to provide incremental or continuous flow of reagent to the air brush dispenser. The air brush dispenser mixes the predetermined incremental quantity or continuous flow of reagent with pressurized air to atomize the reagent and produce an aerosol spray pattern which coats the substrate.
    Type: Grant
    Filed: July 26, 1996
    Date of Patent: April 14, 1998
    Assignee: Bio Dot, Inc.
    Inventor: Thomas C. Tisone