Patents Assigned to Bioengineering Laboratories, LLC
  • Patent number: 9976168
    Abstract: A method is provided for measuring a substance using a biosensor, the method comprising: introducing a sample containing the substance into an electrochemical measurement cell which comprises an insulating base plate; at least two electrodes formed on the insulating base plate; and a reagent layer that is disposed on at least one of the electrodes and comprises an oxidoreductase; applying a voltage to the electrodes; detecting a charge transfer limiting current which is generated due to the transfer of electrons from the substance in the sample to the electrode; and determining the concentration of the substance contained in the sample based on the charge transfer limiting current.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: May 22, 2018
    Assignees: ARKRAY, Inc., BioEngineering Laboratories, LLC
    Inventor: Koji Katsuki
  • Publication number: 20160177365
    Abstract: A method is provided for measuring a substance using a biosensor, the method comprising: introducing a sample containing the substance into an electrochemical measurement cell which comprises an insulating base plate; at least two electrodes formed on the insulating base plate; and a reagent layer that is disposed on at least one of the electrodes and comprises an oxidoreductase; applying a voltage to the electrodes; detecting a charge transfer limiting current which is generated due to the transfer of electrons from the substance in the sample to the electrode; and determining the concentration of the substance contained in the sample based on the charge transfer limiting current.
    Type: Application
    Filed: August 7, 2014
    Publication date: June 23, 2016
    Applicants: ARKRAY, Inc., BioEngineering Laboratories, LLC
    Inventor: Koji Katsuki
  • Patent number: 8641972
    Abstract: The present invention provides a method for measuring a substrate concentration by accumulating an energy resulting from a reaction between a biocatalyst and a substrate recognized by the biocatalyst to a certain level; and using a dependency of an accumulation rate on the substrate concentration as an index; and a apparatus therefor. In particular, the present invention provides a method in which the measurement of the accumulation rate is carried out by measuring a frequency of an energy release in a certain amount of time when the energy accumulated in the capacitor reaches the certain level and is then released.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: February 4, 2014
    Assignees: Bioengineering Laboratories, LLC, Arkray, Inc., Ultizyme International Ltd.
    Inventors: Wakako Tsugawa, Koji Sode
  • Patent number: 8642344
    Abstract: The present invention provides a method for measuring a substrate concentration by accumulating an energy resulting from a reaction between a biocatalyst and a substrate recognized by the biocatalyst to a certain level; and using a dependency of an accumulation rate on the substrate concentration as an index; and a apparatus therefor. In particular, the present invention provides a method in which the measurement of the accumulation rate is carried out by measuring a frequency of an energy release in a certain amount of time when the energy accumulated in the capacitor reaches the certain level and is then released.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: February 4, 2014
    Assignees: Bioengineering Laboratories, LLC, Arkray, Inc., Ultizyme International Ltd.
    Inventors: Wakako Tsugawa, Koji Sode
  • Publication number: 20130015078
    Abstract: The present invention provides a method for measuring a substrate concentration by accumulating an energy resulting from a reaction between a biocatalyst and a substrate recognized by the biocatalyst to a certain level; and using a dependency of an accumulation rate on the substrate concentration as an index; and a apparatus therefor. In particular, the present invention provides a method in which the measurement of the accumulation rate is carried out by measuring a frequency of an energy release in a certain amount of time when the energy accumulated in the capacitor reaches the certain level and is then released.
    Type: Application
    Filed: July 26, 2012
    Publication date: January 17, 2013
    Applicants: Bioengineering Laboratories, LLC, Ultizyme International Ltd., Arkray, Inc.
    Inventors: Wakako Tsugawa, Koji Sode
  • Publication number: 20130015063
    Abstract: The present invention provides a method for measuring a substrate concentration by accumulating an energy resulting from a reaction between a biocatalyst and a substrate recognized by the biocatalyst to a certain level; and using a dependency of an accumulation rate on the substrate concentration as an index; and a apparatus therefor. In particular, the present invention provides a method in which the measurement of the accumulation rate is carried out by measuring a frequency of an energy release in a certain amount of time when the energy accumulated in the capacitor reaches the certain level and is then released.
    Type: Application
    Filed: July 26, 2012
    Publication date: January 17, 2013
    Applicants: Bioengineering Laboratories, LLC, Ultizyme International Ltd., Arkray, Inc.
    Inventors: Wakako Tsugawa, Koji Sode
  • Patent number: 8252236
    Abstract: The present invention provides a method for measuring a substrate concentration by accumulating an energy resulting from a reaction between a biocatalyst and a substrate recognized by the biocatalyst to a certain level; and using a dependency of an accumulation rate on the substrate concentration as an index; and a apparatus therefor. In particular, the present invention provides a method in which the measurement of the accumulation rate is carried out by measuring a frequency of an energy release in a certain amount of time when the energy accumulated in the capacitor reaches the certain level and is then released.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: August 28, 2012
    Assignees: Bioengineering Laboratories, LLC, Arkray, Inc., Ultizyme International Ltd.
    Inventors: Wakako Tsugawa, Koji Sode