Abstract: The invention relates to a process of cross-linking collagen. This process is of the type comprising the formation of amide bonds by means of acylazide groups and is characterized in that the collagen is reacted with diphenylphosphorylazide. The process according to the invention makes it possible to simplify the collagen cross-linking process and to adjust the degree of cross-linking at discretion without introducing any cross-linking agent.
Type:
Grant
Filed:
October 7, 1991
Date of Patent:
November 23, 1993
Assignee:
Bioetica
Inventors:
Herve Petite, Philippe Menasche, Alain Huc
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