Abstract: The present invention concerns the field of bacterial infections, and in particular Group-B Streptococcus (GBS) infections during and after pregnancy. The present invention relates to the use of a composition comprising a strain of Lactobacillus acidophilus, a strain of Lactobacillus rhamnosus, and lactoferrin in the preventive and/or curative treatment of Group-B Streptococcus (GBS) infections.