Patents Assigned to Biofor, Ltd.
  • Pharmacologically enhanced formulations
    Patent number: 5271944
    Abstract: An anti-inflammatory composition in which the active ingredient is micronized to form an intimate admixture which can be administered orally.
    Type: Grant
    Filed: April 5, 1991
    Date of Patent: December 21, 1993
    Assignee: Biofor, Ltd.
    Inventor: Sung J. Lee
  • Fused ring heterocycles and pharmaceutical compositions containing same
    Patent number: 5192791
    Abstract: A novel class of pyrrolidin-2-one and piperidin-2-one compounds in which the nitrogen atom is bonded to an oxyphenyl radical having tertiary-alkyl and tri-methylsilyl substituents. The compounds possess anti-inflammatory, immunomodulatory, analgesic and anti-pyretic activity and they may be combined with excipients to provide formulations which are useful in treating arthritis and conditions associated with that disease.
    Type: Grant
    Filed: August 14, 1990
    Date of Patent: March 9, 1993
    Assignee: Biofor, Ltd.
    Inventor: Sung J. Lee
  • Oxazinone substituted phosphines
    Patent number: 5128330
    Abstract: A new class of phosphines in which the phosphorous atom is bonded directly to the carbon of an oxazinone: ##STR1## In addition to their anti-inflammatory activity, these phosphines are useful as intermediates in producing compounds where the phosphine is replaced by a benzylidine, compounds which have also been proven useful in the treatment of inflammation and other conditions associated with arthritis.
    Type: Grant
    Filed: February 19, 1991
    Date of Patent: July 7, 1992
    Assignee: Biofor, Ltd.
    Inventor: Sung J. Lee
  • Pyrrolidinone compounds and pharamaceutical compositions containing same
    Patent number: 4959482
    Abstract: A novel class of pyrrolidin-2-one and piperidin-2-one compounds in which the nitrogen atom is bonded to an oxyphenyl radical haivng tertiary-alkyl and tri-methylsilyl substituents. The compounds posses anti-inflammatory, immunomodulatory, analgesic and anti-pyretic activity and they may be combined with excipients to provide formulations which are useful in treating arthritis and conditions associated with that disease.
    Type: Grant
    Filed: September 26, 1988
    Date of Patent: September 25, 1990
    Assignee: Biofor, Ltd.
    Inventor: Sung J. Lee
  • Oxaza heterocycles and pharmaceutical compositions containing same
    Patent number: 4892870
    Abstract: A novel class of 5, 6 or 7 member heterocycles which belong to the 3-isoxazolidinone, 2H-1,2-oxazin-3 (4H)-one and 3-isoxazepinone series of compounds and which are substituted at the 4-carbon by a benzylidene radical. The compounds have utility as analgesic agents, immunomodulating agents, anti-inflammatory agents and anti-pyretic agents and they may be combined with excipients to provide formuations which are useful in treating arthritis and conditions generally associated with that disease.
    Type: Grant
    Filed: August 1, 1988
    Date of Patent: January 9, 1990
    Assignee: Biofor, Ltd.
    Inventor: Sung J. Lee