Abstract: The present invention relates to a method for producing butanol using a bacterium capable of biosynthesizing butanol from butyryl-CoA as an intermediate. More particularly, a method for producing butanol, the method comprising generating bytyryl-CoA in a bacterium which contains a gene coding for AdhE (an enzyme responsible for the conversion of butyryl-CoA to butanol) using various methods, and converting the butyryl-CoA into butanol.
Type:
Application
Filed:
December 14, 2007
Publication date:
January 27, 2011
Applicant:
BIOFUELCHEM CO., LTD.
Inventors:
Eleftherios Terry Papoutsakis, Sang Yup Lee, Jin Hwan Park
Abstract: Disclosed herein are a method for producing butanol in yeast having the ability to biosynthesize butanol using butyryl-CoA as an intermediate, the method comprises producing butyryl-CoA in yeast having a CoAT (acetyl-CoA:butyryl-CoA CoA-transferase)-encoding gene introduced thereinto, through various pathways, and then converting the produced butyryl-CoA to butanol.
Type:
Application
Filed:
February 11, 2008
Publication date:
June 10, 2010
Applicant:
BIOFUELCHEM CO., LTD.
Inventors:
Sang Yup Lee, Eleftherios Terry Papoutsakis, Yu-Sin Jang
Abstract: The present invention relates to a recombinant mutant microorganism having enhanced butanol producing capacity and a method for producing butanol using the same. In the microorganism, genes coding for enzymes responsible for the biosynthesis of lactate, ethanol and/or acetate are deleted or attenuated and genes coding for enzymes involved in butanol biosynthesis are introduced and amplified.
Type:
Application
Filed:
December 14, 2007
Publication date:
June 3, 2010
Applicant:
BIOFUELCHEM CO., LTD.
Inventors:
Sang Yup Lee, Jin Hwan Park, Eleftherios Terry Papoutsakis
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