Patents Assigned to Biogaia AB
  • Patent number: 8658157
    Abstract: New strains of Lactobacillus that have been selected for their capability of improved reduction the number of Streptococcus mutans in the mouth of mammals through inhibiting activity in combination with better binding to the oral mucins and dental plaque, thereby preventing, reducing or treating dental caries, and products derived from said strains, including agents for treatment or prophylaxis of caries for administration to humans.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: February 25, 2014
    Assignee: Biogaia AB
    Inventors: Bo Mollstam, Eamonn Connolly
  • Patent number: 8617537
    Abstract: Methods for the controlled activation of the reuterin-production machinery of Lactobacillus reuteri by adding glycerol and other substances during the manufacture of cell-cultures and keeping the produced reuterin in the bacterial cell during preservation and storage. In particular this invention relates to the manufacture of large amounts of L. reuteri that are loaded with reuterin, and the use of such loaded bacteria for applications such as prevention and treatment of diseases, for food applications and the like.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: December 31, 2013
    Assignee: Biogaia AB
    Inventor: Stefan Roos
  • Patent number: 8343483
    Abstract: New strains of Lactobacillus that have been selected for their capability of improved reduction the number of Streptococcus mutans in the mouth of mammals through inhibiting activity in combination with better binding to the oral mucins and dental plaque, thereby preventing, reducing or treating dental caries, and products derived from said strains, including agents for treatment or prophylaxis of caries for administration to humans.
    Type: Grant
    Filed: October 15, 2008
    Date of Patent: January 1, 2013
    Assignee: Biogaia AB
    Inventors: Bo Mollstam, Eamonn Connolly
  • Publication number: 20120121564
    Abstract: The invention herein provides certain strains of lactic acid bacteria selected for their capability of promoting production of IL-10 and consequently proliferation of CD4+CD25+ TR cells, for prophylaxis and/or treatment of infant colic, a method of selecting such strains, and products containing such strains.
    Type: Application
    Filed: January 23, 2012
    Publication date: May 17, 2012
    Applicant: BIOGAIA AB
    Inventors: Eamonn Connolly, Bo Mollstam
  • Patent number: 8114397
    Abstract: Selected strains of Lactobacillus and products containing cells of the selected strains to improve breast milk for feeding to babies, more precisely to increase the levels of the anti-inflammatory cytokine IL10 in the milk and reduce the risk that the feeding baby will develop allergies and simultaneously reduce the cause and thereby the amount of TGF-beta-2 in the milk, thus resulting in reduced risk for the lactating mother to develop mastitis.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: February 14, 2012
    Assignee: Biogaia AB
    Inventors: Bengt Bjorksten, Bo Mollstam
  • Patent number: 8016104
    Abstract: A two-compartment container in which the first compartment has an upper layer and a lower layer and contains a first component that is to be added to the second compartment. Above the first compartment is a dome that is bowed upward and is flexible. Depressing the dome by pushing downward on it causes the lower layer of the first compartment to be ruptured without cutting or rupturing the upper layer, releasing the first component into the second compartment.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: September 13, 2011
    Assignee: Biogaia AB
    Inventor: Per Hjalmarsson
  • Patent number: 7955834
    Abstract: Selected strains of Lactobacillus and products containing cells of the selected strains to improve breast milk for feeding to babies, more precisely to increase the levels of the anti-inflammatory cytokine IL10 in the milk and reduce the risk that the feeding baby will develop allergies and simultaneously reduce the cause and thereby the amount of TGF-beta-2 in the milk, thus resulting in reduced risk for the lactating mother to develop mastitis.
    Type: Grant
    Filed: June 3, 2004
    Date of Patent: June 7, 2011
    Assignee: Biogaia AB
    Inventors: Bengt Bjorksten, Bo Mollstam, Elisabeth Sjoberg
  • Patent number: 7910127
    Abstract: This invention relates to the selection and use of nonpathogenic, lysine-uptake stimulating lactic acid bacteria strains, and products and methods using such strains for example for improvement of fur-coat and claws quality in pet-animals.
    Type: Grant
    Filed: February 26, 2008
    Date of Patent: March 22, 2011
    Assignee: Biogaia AB
    Inventors: Eamonn Connolly, Bo Mollstam
  • Patent number: 7678553
    Abstract: Strains of Lactobacillus which have been selected for their capability of reducing gastrointestinal inflammation, such as that due to Helicobacter pylori, and products derived from these strains, including agents for treatment or prophylaxis of inflammation associated with Helicobacter pylori for administration to humans and include conditioned media in which the selected strains have grown and protein-containing extracts of the conditioned media.
    Type: Grant
    Filed: December 3, 2008
    Date of Patent: March 16, 2010
    Assignee: Biogaia AB
    Inventors: Eamonn Connolly, Bo Mollstam
  • Publication number: 20090304656
    Abstract: Methods for the controlled activation of the reuterin-production machinery of Lactobacillus reuteri by adding glycerol and other substances during the manufacture of cell-cultures and keeping the produced reuterin in the bacterial cell during preservation and storage. In particular this invention relates to the manufacture of large amounts of L. reuteri that are loaded with reuterin, and the use of such loaded bacteria for applications such as prevention and treatment of diseases, for food applications and the like.
    Type: Application
    Filed: June 9, 2009
    Publication date: December 10, 2009
    Applicant: BIOGAIA AB
    Inventor: Stefan Roos
  • Patent number: 7517681
    Abstract: New strains of Lactobacillus that have been selected for their capability of improved reduction the number of Streptococcus mutans in the mouth of mammals through inhibiting activity in combination with better binding to the oral mucins and dental plaque, thereby preventing, reducing or treating dental caries, and products derived from said strains, including agents for treatment or prophylaxis of caries for administration to humans.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: April 14, 2009
    Assignee: Biogaia AB
    Inventors: Bo Mollstam, Eamonn Connolly
  • Patent number: 7374924
    Abstract: The invention herein provides certain strains of lactic acid bacteria selected for their capability of promoting production of IL-10 and consequently proliferation of CD4+CD25+ TR cells, for prophylaxis and/or treatment of infant colic, a method of selecting such strains, and products containing such strains.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: May 20, 2008
    Assignee: Biogaia AB
    Inventors: Eamonn Connolly, Bo Mollstam
  • Patent number: 7105336
    Abstract: Strains of Lactobacillus which have been selected for their capability of reducing gastrointestinal inflammation, such as that due to Helicobacter pylori, and products derived from these strains, including agents for treatment or prophylaxis of inflammation associated with Helicobacter pylori for administration to humans and include conditioned media in which the selected strains have grown and protein-containing extracts of the conditioned media.
    Type: Grant
    Filed: October 7, 2002
    Date of Patent: September 12, 2006
    Assignee: Biogaia AB
    Inventors: Eamonn Connolly, Bo Mollstam
  • Patent number: 6872565
    Abstract: Strains of Lactobacillus that have been selected for their capability of reducing the number of Streptococcus mutans in the mouth of mammals through inhibiting activity in combination with good binding to the oral mucins and dental plaque, Administering the strains in a product such as food, reduces and treats dental caries. Preferred strains are Lactobacillus reuteri strain ATTC PTA-4965 or Lactobacillus reuteri strain ATTC PTA-4964.
    Type: Grant
    Filed: January 29, 2003
    Date of Patent: March 29, 2005
    Assignee: Biogaia AB
    Inventors: Bo Mollstam, Eamonn Connolly
  • Patent number: 6786330
    Abstract: A two-compartment container in which the first compartment has an upper layer and a lower layer and contains a first component that is to be added to the second compartment. Above the first compartment is a dome that is bowed upward and is flexible. Attached to the dome is a cutting means. Depressing the dome by pushing downward on it lowers the cutting means so that either the lower layer only or both the upper and lower layer of the first compartment are cut by the cutting means, releasing the first component into the second compartment. The cutting means may be a simple puncturer, or in the case where the second compartment comprises a beverage container or the like, the cutting means may be part of a tubular wall surrounding the opening through which someone can drink the beverage.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: September 7, 2004
    Assignee: BioGaia AB
    Inventors: Bo Mollstam, Ivan A. Casas, Fredrik Magnusson, Karin Oberg, Filip Sauer
  • Patent number: 6769539
    Abstract: A device comprising a compartment attached to a container that keeps a first component, which may be moisture sensitive, from a second component, preferably a liquid, until a selected time before use. The compartment has improved manufacturability and decreased leakage.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: August 3, 2004
    Assignee: Biogaia AB
    Inventors: Leif Stern, Elisabeth Sjoberg, Bo Mollstam
  • Patent number: 6513650
    Abstract: A two-compartment container in which the first compartment has an upper layer and a lower layer and contains a first component that is to be added to the second compartment. Above the first compartment is a dome that is bowed upward and is flexible. Attached to the dome is a cutting means. Depressing the dome by pushing downward on it lowers the cutting means so that both the upper and lower layer of the first compartment are cut by the cutting means, releasing the first component into the second compartment. The cutting means may be a simple puncturer, or in the case where the second compartment comprises a beverage container or the like, the cutting means may be part of a tubular wall surrounding the opening through which someone can drink the beverage.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: February 4, 2003
    Assignee: Biogaia AB
    Inventors: Bo Mollstam, Ivan A. Casas, Fredrik Magnusson, Karin Oberg, Filip Sauer
  • Patent number: 6454088
    Abstract: A two-part container in which a first compartment for a first component and having an upper and a lower layer is mounted either within or outside a second compartment, for a second component, at the location of a port on the second compartment. Cutting means are provided for cutting both the upper and lower layer and through the port, to release the first component into the second compartment.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: September 24, 2002
    Assignee: Biogaia AB
    Inventors: Bo Mollstam, Ivan A. Casas
  • Patent number: 5534253
    Abstract: A method of improving animal health including selecting at least one L. reuteri strain, characterized by the production of .beta.-hydroxypropionaldehyde, and using the selected strain(s) along with the antibiotic, gentamycin, as an animal treatment, for example, for newly hatched poultry.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 9, 1996
    Assignee: Biogaia AB
    Inventors: Ivan A. Casas, Bo Mollstam
  • Patent number: 5480641
    Abstract: A method of establishing direct feed microorganisms such as Lactobacillus reuteri in the gastrointestinal tract of avian organisms, in which the direct feed microorganisms are added to whey and fed in the form of pellets (compacted whey particles) to the organisms.
    Type: Grant
    Filed: June 15, 1993
    Date of Patent: January 2, 1996
    Assignee: Biogaia AB
    Inventor: Ivan A. Casas-Perez