Abstract: The present invention includes: 1) dissolving a first binder in a first solvent; 2) dissolving a dispersing agent in a solution in which the first binder is dissolved; 3) adding charcoal powder to the solution obtained in 2) and performing homogenous mixing to produce a dispersion in which the charcoal powder is bound to the first binder; 4) spray drying the dispersion obtained in 3) to produce a primary capsule from which the first solvent is removed; 5) dissolving a second binder and a softening agent in a second solvent; 6) homogeneously mixing a coloring agent and the dispersing agent with a solution in which the second binder and the softening agent are dissolved; 7) mixing the primary capsule with the solution obtained in 6) to produce a double capsule dispersion in which the primary capsule is bound to the second binder; and 8) spray-drying the double capsule dispersion to product a double capsule from which the second solvent is removed.
Type:
Grant
Filed:
August 31, 2018
Date of Patent:
December 12, 2023
Assignee:
BIOGENICS, INC.
Inventors:
Chan-Jae Shin, Tae-Sung Ko, Hyun-Gyu Shin, Jeong-Ho Park
Abstract: Provided is a method of solubilizing a poorly soluble/insoluble active material through formation of an oligomer composite, in which a structure having a hydrophobic cavity structure is formed by using oligomers derived from two types of hydrophilic natural polymers and a poorly soluble/insoluble component is encapsulated in the cavity structure, and thus, self-aggregation of the poorly soluble/insoluble material is prevented and simultaneously, thermodynamic stability increases to effectively solubilize the poorly soluble/insoluble material.
Abstract: The present invention provides stabilized antioxidant particles, each of which includes a core consisting of an antioxidant and a first coating layer formed on the surface of the core, wherein the first coating layer is formed by polymerizing at least one ?-lipoic acid or its derivative, a composition including the same, and a method for preparing the same.
Type:
Application
Filed:
August 4, 2008
Publication date:
October 7, 2010
Applicant:
BIOGENICS, INC.
Inventors:
Chul Hwan Kim, Chan Jae Shin, So Yeon Seo, Jung Ae Kwon