Abstract: A device for providing pharmaceutical doses comprising a container, filed with a pharmaceutical composition including glyceryl trinitrate and 1,1,1,2-tetrafluoroethane, or 1,1,1,2,3,3,3-heptafluoropropane, as a propellant, and a valve arranged for delivering aerosol doses of said pharmaceutical composition to the exterior of the container, wherein at least a portion of the device is formed from a polyester.
Abstract: A pharmaceutical tablet or lozenge is described, which comprises a non-absorbable pharmaceutically active agent, in combination with a tablet matrix, arranged for providing controlled and sustained release of said agent into the mouth and gastro-intestinal tract, from a buccal or sub-lingual location. Also disclosed, are buccal tablets formed from non-carigenic sugars and a device for holding a tablet or lozenge in a location within a patient's mouth, from which an active ingredient, from the tablet or lozenge, is releasable by the action of the patient's saliva.
Abstract: Micellized aqueous formulations for fat soluble vitamins, essential nutrients, herb oils and pharmaceutical agents are obtained by a process wherein the fat soluble vitamin, essential nutrient or agent is first admixed with a suitable amount of polyethoxylated castor oil and a pharmaceutically acceptable polyol, such as glycerol to provide a non-aqueous phase. Thereafter, an aqueous phase containing mostly water and optionally a preservative, such as sodium benzoate, is slowly added to the agitated non-aqueous phase in such a manner that the temperature of the non-aqueous phase, including the aqueous phase added thereto, is maintained at an elevated temperature, preferably between approximately 60.degree. to 100.degree. C. After cooling, the final admixture is clear, homogeneous, having micelles of approximately 2 microns or smaller size.