Abstract: A drug delivery device having an axis, the drug delivery device comprising a carrier and an insert, the carrier comprising a first body part having a first recess, a first attachment part attached to the first body part and having a first distal end, a second body part having a second recess an actuator mechanism configured to rotate at least one of the first body part or the second body part with respect to one another about the axis, and an insert configured to be inserted and fixed in the second recess, the insert comprising a second attachment part and an insert body with an insert recess, the second attachment part having a second distal end.

Abstract: The present disclosure relates to a delivery device (2) capable of delivering payload to an internal surface of a subject. In some embodiments, the delivery device may deliver payload to the gastrointestinal tract. In some embodiments, the compositions contain active drug substances. In some embodiments, the active drug substances are low permeable active drug substances.

Abstract: An oral drug delivery device and a pharmaceutical composition is disclosed, the oral drug delivery having a longitudinal axis and extending from a first end to a second end, the oral drug delivery device comprising a cover; a body; a first attachment part having a first distal end and configured to deliver an active drug substance; and an actuator mechanism engaged with the first attachment part and configured to rotate the first attachment part about a first rotation axis forming an angle larger than 45 degrees with the longitudinal axis, the oral drug delivery device configured to break or weaken the cover prior to or during rotation of the first attachment part.

Abstract: The present disclosure relates to a delivery device capable of delivering compositions. In some embodiments, the delivery device may deliver compositions to the gastrointestinal tract. In some embodiments, the compositions contain active drug substances. In some embodiments, the active drug substances are low permeable active drug substances.

Abstract: The present disclosure relates to a delivery device capable of delivering compositions. In some embodiments, the delivery device may deliver compositions to the gastrointestinal tract. In some embodiments, the compositions contain active drug substances. In some embodiments, the active drug substances are low permeable active drug substances.