Abstract: A device for expansion within a blood vessel having a wall defining a lumen in the body. The device comprises an elongated tubular member having proximal and distal extremities and having a longitudinal axis. An expansile member is carried by the distal extremity of the elongated tubular member and is movable between contracted and expanded configurations. A deformable membrane having proximal and distal outer surfaces at least partially covers the expansile member in the expanded configuration. The proximal and distal outer surfaces have substantially different configurations when the expansile member is in the expanded configuration. Deployment means is carried by the proximal extremity of the elongated tubular member and is coupled to the expansile member for moving the expansile member between the contracted and expanded configurations. A handle assembly is carried by the proximal extremity of the elongated tubular member and coupled to said deployment means.

Abstract: A device for expansion within a blood vessel having a wall defining a lumen in the body. The device comprises an elongated tubular member having proximal and distal extremities and having a longitudinal axis. An expansile member is carried by the distal extremity of the elongated tubular member and is movable between contracted and expanded configurations. A deformable membrane having proximal and distal outer surfaces at least partially covers the expansile member in the expanded configuration. The proximal and distal outer surfaces have substantially different configurations when the expansile member is in the expanded configuration. Deployment tool is carried by the proximal extremity of the elongated tubular member and is coupled to the expansile member for moving the expansile member between the contracted and expanded configurations. A handle assembly is carried by the proximal extremity of the elongated tubular member and coupled to said deployment tools.

Abstract: A device for expansion within a blood vessel having a wall defining a lumen in the body. A first elongate tubular member has proximal and distal extremities and has a longitudinal axis. An expansile member is carried by the distal extremity of the first elongate tubular member is and movable between contracted and expanded positions. The expansile member has a predetermined configuration in the expanded position. A deformable membrane covers the expansile member, and is sized so as to be capable of overlying and underlying the expansile member in the expanded position. A deployment mechanism is carried by the proximal extremity of the first elongate tubular member and is adapted to be operated by the human hand for controlling movement of the expansile member between the contracted and expanded positions. A deployment mechanism includes a push-pull wire with proximal and distal extremities and extends through the first elongate tubular member and is coupled to the expansile member.

Abstract: A device for expansion within a blood vessel having a wall defining a lumen in the body. The device comprises an elongated tubular member having proximal and distal extremities and having a longitudinal axis. An expansile member is carried by the distal extremity of the elongated tubular member and is movable between contracted and expanded configurations. A deformable membrane at least partially covers the expansile member and is sized so as to be capable of expanding as the expansile member moves from the contracted configuration to the expanded configuration. Deployment members are carried by the proximal extremity of the elongated tubular member and are coupled to the expansile member. The deployment members are adapted to be capable of moving the expansile member between the contracted and expanded configurations. A handle assembly is carried by the proximal extremity of the elongated tubular member and coupled to the deployment members.

Abstract: A biological sealant comprising a gelatin slurry. The slurry contains gelatin, saline or water and thrombin.

Abstract: A device for introducing and polymerizing polymeric biomaterials in the human body. The device has a first elongate tubular member having proximal and distal extremities and a longitudinal axis. An expansile member is carried by the distal extremity of the first elongate tubular member and is movable between contracted and expanded positions. The expansile member has a predetermined configuration in the expanded position. A deformable membrane covers the expansile member and is sized so as to be capable of overlying and underlying the expansile member in the expanded position. A second elongate tubular member has proximal and distal extremities, a longitudinal axis and a first lumen extending from the proximal to the distal extremity of the second elongate tubular member. The distal extremity of said second elongate tubular member terminates proximal to the distal extremity of said first elongate tubular member and adjacent to said expansile member.

Abstract: A device for expansion within a blood vessel having a wall defining a lumen in the body. A first elongate tubular member has proximal and distal extremities and has a longitudinal axis. An expansile member is carried by the distal extremity of the first elongate tubular member and is movable between contracted and expanded positions. The expansile member has a predetermined configuration in the expanded position. A deformable membrane covers the expansile member and is sized so as to be capable of overlying and underlying the expansile member in the expanded position. A deployment mechanism is carried by the proximal extremity of the first elongate tubular member and is adapted to be operated by the human hand for controlling movement of the expansile member between the contracted and expanded positions. A biological sealant introducer is connected to the first elongate tubular member for introducing a biological sealant into the body proximal to the expansile member and external to the lumen of the vessel.

Abstract: A closure device for percutaneously forming a closure of a puncture in the tissue of human body. The device comprises a flexible elongate tubular member having proximal and distal extremities and a longitudinal axis. The flexible elongate tubular member has a first lumen extending from the proximal extremity to the distal extremity. A closure assembly is carried by the distal extremity of the flexible elongate tubular member and is movable between contracted and expanded positions. The closure assembly includes a closure mechanism covered by an impermeable membrane. A handle is carried by the proximal extremity of the flexible elongate tubular member and is adapted to be grasped by the human hand. A deployment mechanism is carried by the handle and extends through the flexible elongate tubular member and is coupled to the closure assembly for moving the closure assembly from the contracted position to the expanded position.