Patents Assigned to Biokier, Inc.
  • METHOD AND COMPOSITION FOR LOWERING TOTAL SYSTEMIC CHOLESTROL, LDL CHOLESTEROL, AND NON-HDL CHOLESTEROL
    Publication number: 20240165060
    Abstract: The present invention relates to a method and composition of treating a lipid related disease such as diabetes, obesity, hypercholesterolemia, and the like by delivery of butyrate directly to the colon by bypassing the upper digestive tract in combination with a second composition that lowers cholesterol, LDL cholesterol and non-LDL cholesterol.
    Type: Application
    Filed: February 2, 2024
    Publication date: May 23, 2024
    Applicant: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20230190686
    Abstract: A method of treating a lipid related disease by oral delivery of butyric acid to the colon for release from about 5 and about 20 hours.
    Type: Application
    Filed: December 17, 2021
    Publication date: June 22, 2023
    Applicant: BIOKIER, INC.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20230149300
    Abstract: A method of treating diabetes Type 2, prediabetes, and diseases caused thereby, by delivery of butyric acid, to the colon by bypassing the upper digestive tract wherein release is from 0 to about 5 hours.
    Type: Application
    Filed: December 21, 2021
    Publication date: May 18, 2023
    Applicant: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20230133176
    Abstract: The present invention relates to a method of treating diabetes Type II by oral delivery of butyric acid, and a DPP-IV inhibitor such as vildagliptin only to the ileum bypassing the stomach, duodenum and jejunum.
    Type: Application
    Filed: November 4, 2021
    Publication date: May 4, 2023
    Applicant: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20220387305
    Abstract: A method of treating diabetes Type 2 by delivery of butyric acid, bile acid, long-chain fatty acid, or glutamine to the colon by bypassing the upper digestive tract, with the composition combined either by the same or different route of administration with a DPP-IV inhibitor such as vildagliptin.
    Type: Application
    Filed: August 18, 2022
    Publication date: December 8, 2022
    Applicant: Biokier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20220071895
    Abstract: A method of treating diabetes Type 2, prediabetes, and diseases caused thereby, by delivery of butyric acid, to the colon by bypassing the upper digestive tract wherein release is from 0 to about 5 hours.
    Type: Application
    Filed: November 16, 2021
    Publication date: March 10, 2022
    Applicant: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20220054406
    Abstract: The present invention relates to a method of treating diabetes Type II by oral delivery of butyric acid, and a DPP-IV inhibitor such as vildagliptin only to the ileum bypassing the stomach, duodenum and jejunum.
    Type: Application
    Filed: November 4, 2021
    Publication date: February 24, 2022
    Applicant: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • STABILIZED COATED BUTYRATE FOR COLON RELEASE
    Publication number: 20210267919
    Abstract: The present invention relates to coated butyrate and butyrate plus DPP-IV inhibitor tablets. It has been discovered that an inner butyrate core, a first layer neutral polymer which can dissolve in the colon, followed by an outer coating of a composition, which dissolves only in the colon, prevents the interaction of butyrate with these compositions.
    Type: Application
    Filed: February 28, 2020
    Publication date: September 2, 2021
    Applicant: BioKier, Inc.
    Inventors: Jerzy Ryszard Szewczyk, Nicolas D. Kirkland, Troy A. Bartron, JR., Abdul Waseh Basit
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20190262262
    Abstract: The present invention relates to a method of treating diabetes Type II by delivery of butyric acid, bile acid, long-chain fatty acid, or glutamine to the colon by bypassing the upper digestive tract. The composition is combined either by the same or different route of administration with a DPP-IV inhibitor such as vildagliptin.
    Type: Application
    Filed: May 7, 2019
    Publication date: August 29, 2019
    Applicant: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • Composition and method for treatment of NASH
    Patent number: 9314444
    Abstract: The present invention relates to a method of treating NASH or NAFLD by delivery of an effective amount of a composition comprising L-glutamine or butyric acid formulated for release in the colon by bypassing the upper digestive tract and stomach.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: April 19, 2016
    Assignee: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • Composition and method for treatment of diabetes
    Patent number: 9301938
    Abstract: The present invention relates to a method of treating an incretin related disease such as diabetes, obesity and the like by delivery of butyric acid, bile acid, long chain fatty acid or glutamine to the colon by bypassing the upper digestive tract. The composition is combined either by the same or different route of administration with a monoamine reuptake inhibitor such as buproprion.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: April 5, 2016
    Assignee: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20150224081
    Abstract: The present invention relates to a method of treating diabetes Type II by delivery of butyric acid, bile acid, long-chain fatty acid, or glutamine to the colon by bypassing the upper digestive tract. The composition is combined either by the same or different route of administration with a DPP-IV inhibitor such as vildagliptin.
    Type: Application
    Filed: April 24, 2015
    Publication date: August 13, 2015
    Applicant: BIOKIER, INC.
    Inventor: Jerzy Ryszard Szewczyk
  • Composition and method for treatment of diabetes
    Patent number: 9006288
    Abstract: The present invention relates to a method of treating an incretin related disease such as diabetes, obesity and the like by delivery of long chain fatty acid to the colon by bypassing the upper digestive tract.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: April 14, 2015
    Assignee: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20150073057
    Abstract: The present invention relates to a method of treating an incretin related disease such as diabetes, obesity and the like by delivery of metformin to the colon by bypassing the upper digestive tract.
    Type: Application
    Filed: September 6, 2013
    Publication date: March 12, 2015
    Applicant: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20140011876
    Abstract: The present invention relates to a method of treating an incretin related disease such as diabetes, obesity and the like by delivery of long chain fatty acid to the colon by bypassing the upper digestive tract.
    Type: Application
    Filed: September 6, 2013
    Publication date: January 9, 2014
    Applicant: BioKier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • Composition and method for treatment of diabetes
    Patent number: 8470885
    Abstract: The present invention relates to a method of treating an incretin related disease such as diabetes, obesity and the like by delivery of butyric acid, bile acid, long chain fatty acid, or glutamine to the colon by bypassing the upper digestive tract.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: June 25, 2013
    Assignee: Biokier, Inc.
    Inventor: Jerzy Ryszard Szewczyk
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20130102581
    Abstract: The present invention relates to a method of treating an incretin related disease such as diabetes, obesity and the like by delivery of butyric acid, bile acid, long chain fatty acid, or glutamine to the colon by bypassing the upper digestive tract.
    Type: Application
    Filed: October 8, 2012
    Publication date: April 25, 2013
    Applicant: BioKier, Inc.
    Inventor: BioKier, Inc.
  • COMPOSITION AND METHOD FOR TREATMENT OF DIABETES
    Publication number: 20120183617
    Abstract: The present invention relates to a method of treating an incretin related disease such as diabetes, obesity and the like by delivery of butyric acid, bile acid, long chain fatty acid or glutamine to the colon by bypassing the upper digestive tract. The composition is combined either by the same or different route of administration with a monoamine reuptake inhibitor such as buproprion.
    Type: Application
    Filed: September 22, 2010
    Publication date: July 19, 2012
    Applicant: Biokier, Inc.
    Inventor: Jerzy Ryszard Szewczyk