Patents Assigned to Bioland
  • Publication number: 20180201970
    Abstract: A system for measuring sulphite in food samples is provided using a biosensor, a method for determining sulphite in food samples using the biosensor, and the biosensor for measuring the sulphite values in food samples. The system uses an amperometric biosensor having a bi-enzymatic system, a working electrode, a counter electrode and a reference electrode. The bi-enzymatic system has the human sulphite oxidase and peroxidase enzymes, and the immobilisation of the enzymes in the working electrode is carried out via simple physical retention. The mixture of the enzymes is mixed with a chemical mediator by applying a sample to the amperometric biosensor; changing the electrical current upon coming into contact with the analyte to be detected; and amperometrically measuring said electrical current in solutions with continuous agitation, using a constant potential.
    Type: Application
    Filed: April 19, 2016
    Publication date: July 19, 2018
    Applicant: Bioland Microbiosensorses, S.L.
    Inventors: Roberto GONZALEZ RIOJA, Sonia MAZA DEL RIO, Sandra SALLERES ALONSO, Arrate JAUREGUIBEITIA CAYROLS, Irune GONZALEZ URQUIDI, Alai ARANTZAMENDI EGIGUREN
  • Publication number: 20170196227
    Abstract: A biological product for the purification of water, soil, industrial wastewater from chemicals that are resistant to degradation, such as pesticides and oil, contains a composition of strains of bacteria Pseudomonas putida VKPM B-10997, Bacillus subtilis VKPM B-10999, and Rhodococcus erythropolis VKPM Ac-1882 in a weight ratio of (1-2);(1-2):1. The biological product can further contain sorbent, organic and mineral supplements, and stimulating agents. The biological product can be used for the decomposition of degradation-resistant pesticides and oil and has plant growth stimulating and fungicidal activity.
    Type: Application
    Filed: March 22, 2017
    Publication date: July 13, 2017
    Applicants: BIOLAND, Ltd
    Inventors: Liliya Anisimova, Tatyana Markusheva, Aleksandr Kurakov, Andrey Zakutayev
  • Patent number: 8604087
    Abstract: Disclosed is a composition for treating or preventing amyloid-related diseases including 4-O-methylhonokiol as an active ingredient. More specifically, a pharmaceutical composition including 4-O-methylhonokiol, which is effective for treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorder, defective memory, amyloidosis, etc. is disclosed. The inventors of the present disclosure have found out for the first time that 4-O-methylhonokiol inhibits the production of ?-amyloid. It has been confirmed to be useful in treating or preventing amyloid-related diseases. Through animal tests including water maze test and passive avoidance test on mice, 4-O-methylhonokiol has been confirmed to be effective for amyloid-related diseases such as Alzheimer's disease, defective memory, cognitive disorder, and the like.
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: December 10, 2013
    Assignee: Bioland Ltd.
    Inventors: Ki Ho Kim, Ki Soo Kim, Young Heui Kim, Jin Guk Kim, Kyoung Tae Kim, Chang Sung Han, Sang iL Lee
  • Patent number: 8426383
    Abstract: Disclosed is an anti-aging composition for external use on skin, which includes low-molecular weight hyaluronic acids, high-molecular weight hyaluronic acids and polysaccharides extracted from root bark of Ulmus davidiana, as active ingredients. The composition including the low-molecular weight hyaluronic acids, high-molecular weight hyaluronic acids and polysaccharides extracted from root bark of Ulmus davidiana, in a predetermined ratio, shows significantly improved skin-moisturizing, skin elasticity-enhancing and inflammation-alleviating effects, as compared to a composition using one of the above ingredients alone. Therefore, the composition may be widely used as a pharmaceutical or cosmetic anti-aging composition.
    Type: Grant
    Filed: March 12, 2009
    Date of Patent: April 23, 2013
    Assignee: Bioland Ltd.
    Inventors: Ki Ho Kim, Ki Soo Kim, Young Heui Kim, Jin Guk Kim, Kyoung Tae Kim, Chang Sung Han, Kang II Ko
  • Publication number: 20110207830
    Abstract: Disclosed is a composition for treating or preventing amyloid-related diseases including 4-O-methylhonokiol as an active ingredient. More specifically, a pharmaceutical composition including 4-O-methylhonokiol, which is effective for treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorder, defective memory, amyloidosis, etc. is disclosed. The inventors of the present disclosure have found out for the first time that 4-O-methylhonokiol inhibits the production of ?-amyloid. It has been confirmed to be useful in treating or preventing amyloid-related diseases. Through animal tests including water maze test and passive avoidance test on mice, 4-O-methylhonokiol has been confirmed to be effective for amyloid-related diseases such as Alzheimer's disease, defective memory, cognitive disorder, and the like.
    Type: Application
    Filed: September 25, 2009
    Publication date: August 25, 2011
    Applicant: BIOLAND LTD.
    Inventors: Ki Ho Kim, Ki Soo Kim, Young Heui Kim, Jin Guk Kim, Kyoung Tae Kim, Chang Sung Han, Sang iL Lee
  • Publication number: 20110189301
    Abstract: The present invention relates to a method for preparing a contact lens-shaped amniotic dressing and a contact lens-shaped amniotic dressing prepared therefrom for treating ocular surface diseases, which does not require the use of sutures or an adhesion material. The inventive contact lens-shaped amniotic dressing is capable of solving the problems associated with suturing an amniotic membrane, e.g., highly delicate surgical techniques of suturing, long surgery time, stitch abscess, granuloma formation, tissue necrosis, and discomfort of patients; and the problems associated with the use of a support, e.g., the elimination of the support by eye blinking, breaking of the support, and discomfort.
    Type: Application
    Filed: April 15, 2010
    Publication date: August 4, 2011
    Applicant: BIOLAND LTD.
    Inventors: Eun Kyung YANG, Sam Hyun Jung, Sung Po Kim, Ji Hoon Joo, Jong Won Lee, Jong Myoung Hong, Jae Chan Kim, Yeoun Sook Chun, Sung Chun Lee, Kwang III Baik
  • Patent number: 7932232
    Abstract: The present invention is related to novel cosmetic composition comprising beta-fructosyl-L-ascorbic acid derivatives produced by fructose conversion reaction using by ascorbic acidskin whitening cosmetic composition as an cream, skin, lotion, pack and the like.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: April 26, 2011
    Assignees: Bioland Ltd., Korea Research Institute of Bioscience & Biotechnology
    Inventors: Ki Ho Kim, Sang Ki Rhee, Chul Ho Kim, Kang ll Ko, Soo Nam Park, Sang Min Lee
  • Publication number: 20110003769
    Abstract: Disclosed is an anti-aging composition for external use on skin, which includes low-molecular weight hyaluronic acids, high-molecular weight hyaluronic acids and polysaccharides extracted from root bark of Ulmus davidiana, as active ingredients. The composition including the low-molecular weight hyaluronic acids, high-molecular weight hyaluronic acids and polysaccharides extracted from root bark of Ulmus davidiana, in a predetermined ratio, shows significantly improved skin-moisturizing, skin elasticity-enhancing and inflammation-alleviating effects, as compared to a composition using one of the above alone. Therefore, the composition may be widely used as a pharmaceutical or cosmetic anti-aging composition.
    Type: Application
    Filed: March 12, 2009
    Publication date: January 6, 2011
    Applicant: BIOLAND LTD.
    Inventors: Ki Ho Kim, Ki Soo Kim, Young Heui Kim, Jin Guk Kim, Kyoung Tae Kim, Chang Sung Han, Kang Il Ko
  • Publication number: 20090208551
    Abstract: The present invention relates to a biological implantation material and method of preparing the same, which comprises the steps of: (i) treating a tissue derived from animal or human with alcohol; (ii) contacting the said tissue with an enzyme selected from the group consisting of dispase, DNAse, RNAse and pepsin in a solvent; (iii) treating the tissue obtained in step (ii) with alkaline solution; and (iv) treating the tissue obtained in step (iii) with acid solution.
    Type: Application
    Filed: July 10, 2008
    Publication date: August 20, 2009
    Applicant: BIOLAND LTD.
    Inventors: In Seop Kim, Dae Gu Son, Young Chul Jang, Eun Kyung Yang, Sung Po Kim, Jong Myoung Hong, Ji Hoon Joo, Jong Sang Kim, Sam Hyun Jung, Jong Won Lee, Mi Young Kwon
  • Publication number: 20080261901
    Abstract: The present invention is related to novel cosmetic composition comprising ?-fructosyl-L-ascorbic acid derivatives produced by fructose conversion reaction using by ascorbic acid and the compounds shows potent inhibiting effect on the activity of tyrosinase enzyme, therefore, it can be useful as a skin whitening cosmetic composition as an cream, skin, lotion, pack and the like.
    Type: Application
    Filed: February 23, 2005
    Publication date: October 23, 2008
    Applicant: BIOLAND LTD.
    Inventors: Ki Ho Kim, Sang Ki Rhee, Chul Ho Kim, Kang Il Ko, Soo Nam Park, Sang Min Lee
  • Patent number: 6933403
    Abstract: A process for a mono carbonylation of a benzenediol of the formula (I) is characterized in that a benzene diol of the formula (II) is reacted with an acid anhydride or carbonyl halide of the formula (III) without any organic or inorganic bases for thereby producing a monocarbonylated benzenediol of the formula (I): wherein R is hydrogen, C1-C15 alkyl group, cycle alkyl group, aryl group, alkoxy group, aryloxy group, dialkylamino group, alkylarylamino group or diarylamino group, and X is a general leaving group such as fluoride, chloride, bromide, iodide, acetoxy, etc.
    Type: Grant
    Filed: October 14, 2002
    Date of Patent: August 23, 2005
    Assignees: Bioland Co., Ltd., Korea Research Institute of Chemical Technology
    Inventors: Yeon-Soo Lee, Bum-Tae Kim, Yong-Ki Min, No-Kyun Park, Ki-Ho Kim, Ki-Soo Kim
  • Publication number: 20010053846
    Abstract: The invention is related to a preparation method of arbutin intermediate (chemical formula I). It is characterized by the glycosylation of hydroquinone or mono-protectected hydroquinone (chemical formula II) with pentaacetyl-&bgr;-D-glucose (chemical formula III) in the presence of Lewis acid and base as catalysts.
    Type: Application
    Filed: April 20, 2001
    Publication date: December 20, 2001
    Applicant: Bioland Co., Ltd.
    Inventors: Yeon Soo Lee, Bum Tae Kim, Yong Ki Min, No Kyum Park, Ki Ho Kim, Jae Seob Lee, See Wha Jeoung, Ki Soo Kim
  • Patent number: 6217614
    Abstract: The present invention concerns a process for treating bone tissue of animal or human origin, and a corresponding implantable biomaterial. According to the present invention, a fluid in the supercritical state is caused to penetrate throughout the bone tissue. The bone tissue thus treated can then undergo stages of extracting specific proteins. This tissue is intended to be placed on a damaged bone tissue and has mechanical properties at least equivalent to those of natural bone.
    Type: Grant
    Filed: January 16, 1998
    Date of Patent: April 17, 2001
    Assignee: Bioland
    Inventors: Jacques Fages, Alain Marty, Didier Combes, Jean-Stéphane Condoret
  • Patent number: 6120558
    Abstract: A method for treating after its manufacture a textile structure containing at least one polymer of the poly (.alpha.-hydroxy-acids) family obtained by at least one step of mechanical assembly of textile fibers. The structure is contacted with a flow of a composition of at least one fluid in supercritical state. The invention also concerns a method for manufacturing a structure and the resulting structure.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: September 19, 2000
    Assignee: Bioland
    Inventors: Nicolas Poddevin, Jacques Fages, Robert Guidoin
  • Patent number: 6018095
    Abstract: A method for preparing a composite material for implantation into a biological medium, by preparing at least one block of solid porous matrix including at least one calcium salt; preparing a liquid solution hardenable into a solid composition including at least one calcium salt; dipping the matrix block into the liquid solution; and drying and hardening the liquid solution. The resulting composite material, an implant including the material, and a kit for extemporaneously carrying out the method, are also disclosed.
    Type: Grant
    Filed: January 22, 1998
    Date of Patent: January 25, 2000
    Assignee: Bioland
    Inventors: Alain Lerch, Patrick Frayssinet
  • Patent number: 5725579
    Abstract: The present invention concerns a process for treating bone tissue of animal or human origin, and a corresponding implantable biomaterial. According to the present invention, a fluid in the supercritical state is caused to penetrate throughout the bone tissue. The bone tissue thus treated can then undergo stages of extracting specific proteins. This tissue is intended to be placed on a damaged bone tissue and has mechanical properties at least equivalent to those of natural bone.
    Type: Grant
    Filed: December 6, 1995
    Date of Patent: March 10, 1998
    Assignee: Bioland
    Inventors: Jacques Fages, Alain Marty, Didier Combes, Jean-Stephane Condoret
  • Patent number: 5723012
    Abstract: The invention concerns the use with the aim of antiviral prophylaxis of a current of carbon dioxide CO.sub.2 in the supercritical state in contact with a tissue having a collagenous network of human or animal origin intended to be used as or in an implantable supporting tissue prosthesis as a biomaterial, wherein carbon dioxide in the supercritical state has the function of eliminating viral contamination from the tissue.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: March 3, 1998
    Assignee: Bioland
    Inventors: Jacques Fages, Patrick Frayssinet, Gilbert Bonel