Patents Assigned to Bioland
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Publication number: 20180201970Abstract: A system for measuring sulphite in food samples is provided using a biosensor, a method for determining sulphite in food samples using the biosensor, and the biosensor for measuring the sulphite values in food samples. The system uses an amperometric biosensor having a bi-enzymatic system, a working electrode, a counter electrode and a reference electrode. The bi-enzymatic system has the human sulphite oxidase and peroxidase enzymes, and the immobilisation of the enzymes in the working electrode is carried out via simple physical retention. The mixture of the enzymes is mixed with a chemical mediator by applying a sample to the amperometric biosensor; changing the electrical current upon coming into contact with the analyte to be detected; and amperometrically measuring said electrical current in solutions with continuous agitation, using a constant potential.Type: ApplicationFiled: April 19, 2016Publication date: July 19, 2018Applicant: Bioland Microbiosensorses, S.L.Inventors: Roberto GONZALEZ RIOJA, Sonia MAZA DEL RIO, Sandra SALLERES ALONSO, Arrate JAUREGUIBEITIA CAYROLS, Irune GONZALEZ URQUIDI, Alai ARANTZAMENDI EGIGUREN
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Publication number: 20170196227Abstract: A biological product for the purification of water, soil, industrial wastewater from chemicals that are resistant to degradation, such as pesticides and oil, contains a composition of strains of bacteria Pseudomonas putida VKPM B-10997, Bacillus subtilis VKPM B-10999, and Rhodococcus erythropolis VKPM Ac-1882 in a weight ratio of (1-2);(1-2):1. The biological product can further contain sorbent, organic and mineral supplements, and stimulating agents. The biological product can be used for the decomposition of degradation-resistant pesticides and oil and has plant growth stimulating and fungicidal activity.Type: ApplicationFiled: March 22, 2017Publication date: July 13, 2017Applicants: BIOLAND, LtdInventors: Liliya Anisimova, Tatyana Markusheva, Aleksandr Kurakov, Andrey Zakutayev
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Patent number: 8604087Abstract: Disclosed is a composition for treating or preventing amyloid-related diseases including 4-O-methylhonokiol as an active ingredient. More specifically, a pharmaceutical composition including 4-O-methylhonokiol, which is effective for treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorder, defective memory, amyloidosis, etc. is disclosed. The inventors of the present disclosure have found out for the first time that 4-O-methylhonokiol inhibits the production of ?-amyloid. It has been confirmed to be useful in treating or preventing amyloid-related diseases. Through animal tests including water maze test and passive avoidance test on mice, 4-O-methylhonokiol has been confirmed to be effective for amyloid-related diseases such as Alzheimer's disease, defective memory, cognitive disorder, and the like.Type: GrantFiled: September 25, 2009Date of Patent: December 10, 2013Assignee: Bioland Ltd.Inventors: Ki Ho Kim, Ki Soo Kim, Young Heui Kim, Jin Guk Kim, Kyoung Tae Kim, Chang Sung Han, Sang iL Lee
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Patent number: 8426383Abstract: Disclosed is an anti-aging composition for external use on skin, which includes low-molecular weight hyaluronic acids, high-molecular weight hyaluronic acids and polysaccharides extracted from root bark of Ulmus davidiana, as active ingredients. The composition including the low-molecular weight hyaluronic acids, high-molecular weight hyaluronic acids and polysaccharides extracted from root bark of Ulmus davidiana, in a predetermined ratio, shows significantly improved skin-moisturizing, skin elasticity-enhancing and inflammation-alleviating effects, as compared to a composition using one of the above ingredients alone. Therefore, the composition may be widely used as a pharmaceutical or cosmetic anti-aging composition.Type: GrantFiled: March 12, 2009Date of Patent: April 23, 2013Assignee: Bioland Ltd.Inventors: Ki Ho Kim, Ki Soo Kim, Young Heui Kim, Jin Guk Kim, Kyoung Tae Kim, Chang Sung Han, Kang II Ko
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Publication number: 20110207830Abstract: Disclosed is a composition for treating or preventing amyloid-related diseases including 4-O-methylhonokiol as an active ingredient. More specifically, a pharmaceutical composition including 4-O-methylhonokiol, which is effective for treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorder, defective memory, amyloidosis, etc. is disclosed. The inventors of the present disclosure have found out for the first time that 4-O-methylhonokiol inhibits the production of ?-amyloid. It has been confirmed to be useful in treating or preventing amyloid-related diseases. Through animal tests including water maze test and passive avoidance test on mice, 4-O-methylhonokiol has been confirmed to be effective for amyloid-related diseases such as Alzheimer's disease, defective memory, cognitive disorder, and the like.Type: ApplicationFiled: September 25, 2009Publication date: August 25, 2011Applicant: BIOLAND LTD.Inventors: Ki Ho Kim, Ki Soo Kim, Young Heui Kim, Jin Guk Kim, Kyoung Tae Kim, Chang Sung Han, Sang iL Lee
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Publication number: 20110189301Abstract: The present invention relates to a method for preparing a contact lens-shaped amniotic dressing and a contact lens-shaped amniotic dressing prepared therefrom for treating ocular surface diseases, which does not require the use of sutures or an adhesion material. The inventive contact lens-shaped amniotic dressing is capable of solving the problems associated with suturing an amniotic membrane, e.g., highly delicate surgical techniques of suturing, long surgery time, stitch abscess, granuloma formation, tissue necrosis, and discomfort of patients; and the problems associated with the use of a support, e.g., the elimination of the support by eye blinking, breaking of the support, and discomfort.Type: ApplicationFiled: April 15, 2010Publication date: August 4, 2011Applicant: BIOLAND LTD.Inventors: Eun Kyung YANG, Sam Hyun Jung, Sung Po Kim, Ji Hoon Joo, Jong Won Lee, Jong Myoung Hong, Jae Chan Kim, Yeoun Sook Chun, Sung Chun Lee, Kwang III Baik
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Patent number: 7932232Abstract: The present invention is related to novel cosmetic composition comprising beta-fructosyl-L-ascorbic acid derivatives produced by fructose conversion reaction using by ascorbic acidskin whitening cosmetic composition as an cream, skin, lotion, pack and the like.Type: GrantFiled: February 23, 2005Date of Patent: April 26, 2011Assignees: Bioland Ltd., Korea Research Institute of Bioscience & BiotechnologyInventors: Ki Ho Kim, Sang Ki Rhee, Chul Ho Kim, Kang ll Ko, Soo Nam Park, Sang Min Lee
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Publication number: 20110003769Abstract: Disclosed is an anti-aging composition for external use on skin, which includes low-molecular weight hyaluronic acids, high-molecular weight hyaluronic acids and polysaccharides extracted from root bark of Ulmus davidiana, as active ingredients. The composition including the low-molecular weight hyaluronic acids, high-molecular weight hyaluronic acids and polysaccharides extracted from root bark of Ulmus davidiana, in a predetermined ratio, shows significantly improved skin-moisturizing, skin elasticity-enhancing and inflammation-alleviating effects, as compared to a composition using one of the above alone. Therefore, the composition may be widely used as a pharmaceutical or cosmetic anti-aging composition.Type: ApplicationFiled: March 12, 2009Publication date: January 6, 2011Applicant: BIOLAND LTD.Inventors: Ki Ho Kim, Ki Soo Kim, Young Heui Kim, Jin Guk Kim, Kyoung Tae Kim, Chang Sung Han, Kang Il Ko
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Publication number: 20090208551Abstract: The present invention relates to a biological implantation material and method of preparing the same, which comprises the steps of: (i) treating a tissue derived from animal or human with alcohol; (ii) contacting the said tissue with an enzyme selected from the group consisting of dispase, DNAse, RNAse and pepsin in a solvent; (iii) treating the tissue obtained in step (ii) with alkaline solution; and (iv) treating the tissue obtained in step (iii) with acid solution.Type: ApplicationFiled: July 10, 2008Publication date: August 20, 2009Applicant: BIOLAND LTD.Inventors: In Seop Kim, Dae Gu Son, Young Chul Jang, Eun Kyung Yang, Sung Po Kim, Jong Myoung Hong, Ji Hoon Joo, Jong Sang Kim, Sam Hyun Jung, Jong Won Lee, Mi Young Kwon
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Publication number: 20080261901Abstract: The present invention is related to novel cosmetic composition comprising ?-fructosyl-L-ascorbic acid derivatives produced by fructose conversion reaction using by ascorbic acid and the compounds shows potent inhibiting effect on the activity of tyrosinase enzyme, therefore, it can be useful as a skin whitening cosmetic composition as an cream, skin, lotion, pack and the like.Type: ApplicationFiled: February 23, 2005Publication date: October 23, 2008Applicant: BIOLAND LTD.Inventors: Ki Ho Kim, Sang Ki Rhee, Chul Ho Kim, Kang Il Ko, Soo Nam Park, Sang Min Lee
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Patent number: 6933403Abstract: A process for a mono carbonylation of a benzenediol of the formula (I) is characterized in that a benzene diol of the formula (II) is reacted with an acid anhydride or carbonyl halide of the formula (III) without any organic or inorganic bases for thereby producing a monocarbonylated benzenediol of the formula (I): wherein R is hydrogen, C1-C15 alkyl group, cycle alkyl group, aryl group, alkoxy group, aryloxy group, dialkylamino group, alkylarylamino group or diarylamino group, and X is a general leaving group such as fluoride, chloride, bromide, iodide, acetoxy, etc.Type: GrantFiled: October 14, 2002Date of Patent: August 23, 2005Assignees: Bioland Co., Ltd., Korea Research Institute of Chemical TechnologyInventors: Yeon-Soo Lee, Bum-Tae Kim, Yong-Ki Min, No-Kyun Park, Ki-Ho Kim, Ki-Soo Kim
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Publication number: 20010053846Abstract: The invention is related to a preparation method of arbutin intermediate (chemical formula I). It is characterized by the glycosylation of hydroquinone or mono-protectected hydroquinone (chemical formula II) with pentaacetyl-&bgr;-D-glucose (chemical formula III) in the presence of Lewis acid and base as catalysts.Type: ApplicationFiled: April 20, 2001Publication date: December 20, 2001Applicant: Bioland Co., Ltd.Inventors: Yeon Soo Lee, Bum Tae Kim, Yong Ki Min, No Kyum Park, Ki Ho Kim, Jae Seob Lee, See Wha Jeoung, Ki Soo Kim
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Patent number: 6217614Abstract: The present invention concerns a process for treating bone tissue of animal or human origin, and a corresponding implantable biomaterial. According to the present invention, a fluid in the supercritical state is caused to penetrate throughout the bone tissue. The bone tissue thus treated can then undergo stages of extracting specific proteins. This tissue is intended to be placed on a damaged bone tissue and has mechanical properties at least equivalent to those of natural bone.Type: GrantFiled: January 16, 1998Date of Patent: April 17, 2001Assignee: BiolandInventors: Jacques Fages, Alain Marty, Didier Combes, Jean-Stéphane Condoret
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Patent number: 6120558Abstract: A method for treating after its manufacture a textile structure containing at least one polymer of the poly (.alpha.-hydroxy-acids) family obtained by at least one step of mechanical assembly of textile fibers. The structure is contacted with a flow of a composition of at least one fluid in supercritical state. The invention also concerns a method for manufacturing a structure and the resulting structure.Type: GrantFiled: December 18, 1998Date of Patent: September 19, 2000Assignee: BiolandInventors: Nicolas Poddevin, Jacques Fages, Robert Guidoin
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Patent number: 6018095Abstract: A method for preparing a composite material for implantation into a biological medium, by preparing at least one block of solid porous matrix including at least one calcium salt; preparing a liquid solution hardenable into a solid composition including at least one calcium salt; dipping the matrix block into the liquid solution; and drying and hardening the liquid solution. The resulting composite material, an implant including the material, and a kit for extemporaneously carrying out the method, are also disclosed.Type: GrantFiled: January 22, 1998Date of Patent: January 25, 2000Assignee: BiolandInventors: Alain Lerch, Patrick Frayssinet
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Patent number: 5725579Abstract: The present invention concerns a process for treating bone tissue of animal or human origin, and a corresponding implantable biomaterial. According to the present invention, a fluid in the supercritical state is caused to penetrate throughout the bone tissue. The bone tissue thus treated can then undergo stages of extracting specific proteins. This tissue is intended to be placed on a damaged bone tissue and has mechanical properties at least equivalent to those of natural bone.Type: GrantFiled: December 6, 1995Date of Patent: March 10, 1998Assignee: BiolandInventors: Jacques Fages, Alain Marty, Didier Combes, Jean-Stephane Condoret
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Patent number: 5723012Abstract: The invention concerns the use with the aim of antiviral prophylaxis of a current of carbon dioxide CO.sub.2 in the supercritical state in contact with a tissue having a collagenous network of human or animal origin intended to be used as or in an implantable supporting tissue prosthesis as a biomaterial, wherein carbon dioxide in the supercritical state has the function of eliminating viral contamination from the tissue.Type: GrantFiled: December 21, 1995Date of Patent: March 3, 1998Assignee: BiolandInventors: Jacques Fages, Patrick Frayssinet, Gilbert Bonel