Patents Assigned to Biolano Co., Ltd.
  • Preparation method of arbutin intermediates
    Patent number: 6388103
    Abstract: The invention is related to a preparation method of arbutin intermediate (chemical formula I). It is characterized by the glycosylation of hydroquinone or mono-protectected hydroquinone (chemical formula II) with pentaacetyl-&bgr;-D-glucose (chemical formula III) in the presence of Lewis acid and base as catalysts. where Ac is acetyl group, R is hydrogen, alkyl or cycloalkyl group with 1 to 10 carbon, or aliphatic or aromatic acyl group with 1 to 10 carbon.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: May 14, 2002
    Assignees: Korea Research Institute of Chemical Technology, Biolano Co., Ltd.
    Inventors: Yeon Soo Lee, Bum Tae Kim, Yong Ki Min, No Kyun Park, Ki Ho Kim, Jae Seob Lee, See Wha Jeoung, Ki Soo Kim