Patents Assigned to Bioline Limited
  • Method for Enhancing Enzymatic DNA Polymerase Reactions
    Publication number: 20090170090
    Abstract: The invention relates to a method of enhancing a DNA polymerase reaction by including in a reaction mixture containing a DNA polymerase a protein of DNA ligase.
    Type: Application
    Filed: November 15, 2006
    Publication date: July 2, 2009
    Applicant: BIOLINE LIMITED
    Inventors: Konstantin Ignatov, Vladimir Kramarov, Dimitrij Plachov
  • Thermostable DNA polymerase
    Patent number: 6630319
    Abstract: The present invention relates to an enzyme which has the properties of thermostability, DNA polymerase activity and proof-reading, said properties being derived from at least two different sources, wherein the properties are preferably in synergistic combination. Further, the invention relates to a thermostable DNA polymerase, wherein the enzyme contains a proof-reading function derived from an enzyme of one species and a polymerase function derived from an enzyme of a different species.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: October 7, 2003
    Assignee: Bioline Limited
    Inventors: Vladimir Matveevich Kramarov, Konstantin Borisovich Ignatov, James Peter Hallinan