Patents Assigned to Biolog Life Science Institute Forshungslabor und Biochemica-Vertrieb GmbH
  • NAD analogs and methods of using said NAD analogs in determining ribosylation of proteins with PARP mutants
    Patent number: 9926340
    Abstract: The present disclosure provides NAD analogs of the formula: wherein R1, n, and X1 are defined herein, useful for the identification of PARP target proteins and the amino acid sequence wherein the ribose group is attached to the target protein. Also, provided herein are methods of identifying target protein and amino acid sequences. Additionally, the present disclosure provides methods of identifying DNA sequences associated with specific chromatin proteins.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: March 27, 2018
    Assignees: The Board of Regents of the University of Texas System, Biolog Life Science Institute Forshungslabor und Biochemica-Vertrieb GmbH, Cornell University
    Inventors: W. Lee Kraus, Bryan A. Gibson, Frank Schwede, Hening Lin