Abstract: In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein.

Abstract: Apparatus are provided for regulating intra-oral light therapy. Such apparatus includes an oral tray, a plurality of light emitters configured to overlie and irradiate mucosal tissue overlying one or more roots of a plurality of teeth, an extra-oral bridge connected to the oral tray, and a housing connected to the extra-oral bridge. The light from the light emitters can be activated for a duration from about 1 minute to about 20 minutes and have a wavelength in the range of about 845 nm to about 865 nm.

Abstract: In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein.

Abstract: In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein.

Abstract: Apparatus are provided for regulating intra-oral light therapy. Such apparatus includes an oral tray, a plurality of light emitters configured to overlie and irradiate mucosal tissue overlying one or more roots of a plurality of teeth, an extra-oral bridge connected to the oral tray, and a housing connected to the extra-oral bridge. The light from the light emitters can be activated for a duration from about 1 minute to about 20 minutes and have a wavelength in the range of about 845 nm to about 865 nm. The apparatus includes an intra-oral tray with light emitters having a light wavelength ranging from about 845 nm to about 865 nm.

Abstract: In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein.

Abstract: In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein.

Abstract: Photodynamic light therapy apparatus and methods for treating oral disease are disclosed where one method for reducing or eliminating microbial biofilm or plaque and inflammation in a microbial infected area of the mouth generally comprises treating the microbial infected area with a photosensitizer and simultaneously treating the microbial infected area with an intra-oral low level energy device.

Abstract: The disclosure relates generally to methods for treating or slowing progression of a tumor, a neurodegenerative disease or a cognitive impairment, and for improving cognition, comprising administration of light therapy. The disclosure also relates to methods for activating oral stem cells, comprising administration of light therapy. Further provided herein are methods for improving cognition, comprising administering to the oral cavity of a subject in need thereof an effective amount of light. Additionally provided herein are methods for treating autism or Asperger's syndrome, comprising administering to the oral cavity of a subject in need thereof an effective amount of light.