Patents Assigned to Biolyph, LLC
  • Patent number: 12350678
    Abstract: A reagent cartridge includes a cartridge body configured to store a solid reagent, the cartridge body having a reagent well accessible through an access port. A seal plate is proximate the access port, the seal plate extends away from the access port to a seal plate edge remote from the access port. The reagent cartridge includes an isolation envelope surrounding the reagent well. The isolation envelope includes a seal membrane covering the access port, at least one isolation wall, and at least one isolation cavity interposed between the isolation wall and the well sidewall. One or more reagent cartridges are received in a cartridge magazine. The cartridge magazine includes at least one complementary profile seat configured to receive the one or more reagent cartridges having a corresponding cartridge profile.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: July 8, 2025
    Assignee: BIOLYPH, LLC
    Inventors: Timothy E. Pearcy, Steve Rose
  • Patent number: 11819852
    Abstract: A reagent preparation assembly includes a body and a reaction chamber adjacent the body, the reaction chamber includes a reagent therein, such as a lyophilized reagent. An access port extends into the reaction chamber, and the access port is configured to receive an instrument. A seal extends across a portion of the reaction chamber and the access port. A reconstitution assembly is movably coupled with the body. The reconstitution assembly includes a plunger, a syringe and a piston. The plunger is movably coupled with the body. The syringe is selectively engaged with the plunger. The syringe includes a solution reservoir containing a solution, and movement of the syringe pierces the seal. The piston is selectively engaged with the plunger, and the piston is movably coupled within the syringe. Movement of the piston pushes the solution into the reaction chamber.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: November 21, 2023
    Assignee: Biolyph, LLC
    Inventors: Timothy E. Pearcy, James G. Skakoon
  • Patent number: 10668473
    Abstract: A reagent preparation assembly includes a body and a reaction chamber adjacent the body, the reaction chamber includes a reagent therein, such as a lyophilized reagent. An access port extends into the reaction chamber, and the access port is configured to receive an instrument. A seal extends across a portion of the reaction chamber and the access port. A reconstitution assembly is movably coupled with the body. The reconstitution assembly includes a plunger, a syringe and a piston. The plunger is movably coupled with the body. The syringe is selectively engaged with the plunger. The syringe includes a solution reservoir containing a solution, and movement of the syringe pierces the seal. The piston is selectively engaged with the plunger, and the piston is movably coupled within the syringe. Movement of the piston pushes the solution into the reaction chamber.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: June 2, 2020
    Assignee: Biolyph, LLC
    Inventors: Timothy Pearcy, James G. Skakoon
  • Patent number: 10406524
    Abstract: A reagent preparation assembly includes a body and a reaction chamber adjacent the body, the reaction chamber includes a reagent therein, such as a lyophilized reagent. An access port extends into the reaction chamber, and the access port is configured to receive an instrument. A seal extends across a portion of the reaction chamber and the access port. A reconstitution assembly is movably coupled with the body. The reconstitution assembly includes a plunger, a syringe and a piston. The plunger is movably coupled with the body. The syringe is selectively engaged with the plunger. The syringe includes a solution reservoir containing a solution, and movement of the syringe pierces the seal. The piston is selectively engaged with the plunger, and the piston is movably coupled within the syringe. Movement of the piston pushes the solution into the reaction chamber.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: September 10, 2019
    Assignee: Biolyph, LLC
    Inventors: Timothy Pearcy, James G. Skakoon
  • Publication number: 20140048556
    Abstract: A reagent preparation and dispensing device includes a body having a reaction chamber for a reagent and a solution reservoir for a solution. The solution reservoir is isolated from the reaction chamber. A plunger is movably coupled with the body. Movement of the plunger from a starting position to a seated position pushes the solution into the reaction chamber. A dispensing path extends from the reaction chamber out of the body. The dispensing path is configured to dispense a reagent mixture formed from the solution and the reagent. A vent path extends from the reaction chamber, the vent path vents reaction chamber gas displaced by the addition of the solution to the reaction chamber throughout movement of the plunger from the starting position to the seated position.
    Type: Application
    Filed: November 18, 2010
    Publication date: February 20, 2014
    Applicant: Biolyph, LLC
    Inventors: Timothy Pearcy, James G. Skakoon
  • Publication number: 20130208558
    Abstract: A reagent preparation assembly includes a body and a reaction chamber adjacent the body, the reaction chamber includes a reagent therein, such as a lyophilized reagent. An access port extends into the reaction chamber, and the access port is configured to receive an instrument. A seal extends across a portion of the reaction chamber and the access port. A reconstitution assembly is movably coupled with the body. The reconstitution assembly includes a plunger, a syringe and a piston. The plunger is movably coupled with the body. The syringe is selectively engaged with the plunger. The syringe includes a solution reservoir containing a solution, and movement of the syringe pierces the seal. The piston is selectively engaged with the plunger, and the piston is movably coupled within the syringe. Movement of the piston pushes the solution into the reaction chamber.
    Type: Application
    Filed: June 29, 2011
    Publication date: August 15, 2013
    Applicant: Biolyph LLC
    Inventors: Timothy Pearcy, James G. Skakoon
  • Patent number: 8329119
    Abstract: A reagent preparation and dispensing device includes a body. A reagent reservoir containing a reagent is disposed within the body. A solution reservoir containing a solution is disposed within the body. The device further includes an activator movably coupled with the body to open the reagent reservoir and the solution reservoir. The activator is operable to mix the solution with the reagent to form a reagent mixture. A dispensing reservoir tip is coupled with the body. The dispensing reservoir tip is sized and shaped to dispense the reagent mixture from the device.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: December 11, 2012
    Assignee: Biolyph, LLC
    Inventors: Timothy Pearcy, James G. Skakoon
  • Publication number: 20120201726
    Abstract: A reagent preparation and dispensing device includes a body. A reagent reservoir containing a reagent is disposed within the body. A solution reservoir containing a solution is disposed within the body. The device further includes an activator movably coupled with the body to open the reagent reservoir and the solution reservoir. The activator is operable to mix the solution with the reagent to form a reagent mixture. A dispensing reservoir tip is coupled with the body. The dispensing reservoir tip is sized and shaped to dispense the reagent mixture from the device.
    Type: Application
    Filed: April 18, 2012
    Publication date: August 9, 2012
    Applicant: Biolyph, LLC
    Inventors: Timothy Pearcy, James G. Skakoon
  • Publication number: 20110127294
    Abstract: A reagent preparation and dispensing device includes a body. A reagent reservoir containing a reagent is disposed within the body. A solution reservoir containing a solution is disposed within the body. The device further includes an activator movably coupled with the body to open the reagent reservoir and the solution reservoir, The activator is operable to mix the solution with the reagent to form a specified amount of a reagent mixture. A dispensing reservoir tip is coupled with the body. The dispensing reservoir tip is sized and shaped to hold the specified amount of the reagent mixture and dispense the specified amount of the reagent mixture from the device.
    Type: Application
    Filed: May 14, 2009
    Publication date: June 2, 2011
    Applicant: Biolyph, LLC
    Inventors: Timothy Pearcy, James G. Skakoon