Patents Assigned to BIOM'UP
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Patent number: 11052172Abstract: The invention relates to a kit to prepare an hemostatic flowable comprising: —A hemostatic powder having a composition comprising: ?non-cross-linked collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen; ?at least one monosaccharide; and ?at least one glycosaminoglycan; —A saline solution to be mixed with the hemostatic powder in order to form the hemostatic flowable. The invention also relates to a method for preparing an hemostatic flowable with such a kit, comprising the steps of: a. Providing the hemostatic powder in a container; b. Adding a quantity of the saline solution in the container enclosing the hemostatic powder, closing and shaking said container in order to promote hydration of the hemostatic powder to form the hemostatic flowable.Type: GrantFiled: August 11, 2017Date of Patent: July 6, 2021Assignee: BIOM'UP FRANCE SASInventors: William Spotnitz, Valérie Centis, Doris Moura Campos, Alexia De Gasperis
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Publication number: 20210162095Abstract: The invention relates to a printed hemostatic product having at least three-dimensions and being made of a stack of layers deposited on one another from a first external layer up to a second external layer, wherein adjacent layers of the stack of layers are joined together, and wherein at least one layer of the stack of layers has at least one portion made from an hemostatic flowable with a composition comprising: non-cross-linked collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen; and—at least one monosaccharide. The invention also relates to a method for forming such an hemostatic product with a three-dimensional additive printer, and the use of an hemostatic flowable as a printing ink in such a three-dimensional additive printer.Type: ApplicationFiled: February 15, 2019Publication date: June 3, 2021Applicant: BIOM'UP FRANCE SASInventors: Valérie CENTIS, Emmanuelle MONCHAUX
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Publication number: 20190282676Abstract: The invention relates to a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glyclosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.Type: ApplicationFiled: May 23, 2019Publication date: September 19, 2019Applicant: BIOM'UPInventors: Christian GAGNIEU, Patricia FOREST, Sylvain PICOT
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Patent number: 10342856Abstract: The invention relates to a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.Type: GrantFiled: July 13, 2018Date of Patent: July 9, 2019Assignee: BIOM'UPInventors: Christian Gagnieu, Patricia Forest, Sylvain Picot
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Patent number: 10283015Abstract: A device to simulate a surface bleeding is provided. The device includes A source of a blood liquid; A pump system connected to the source of blood liquid and configured to provide a controlled flow of said blood liquid; A wound simulator having an open chamber connected to the pump system to receive the controlled flow of blood liquid, wherein the wound simulator includes a set of interchangeable plates having a plurality of holes arranged through said plates according to a specific pattern, and each plate being adapted to be removably mounted on the wound simulator to close the open chamber, so that blood liquid flows out of the chamber through the holes of the plate mounted on the wound simulator.Type: GrantFiled: April 8, 2015Date of Patent: May 7, 2019Assignee: Biom'UpInventors: William Spotnitz, Patricia Forest, Catherine Wittmann, Vincent Guyot, Sylvain Picot
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Publication number: 20180318403Abstract: The invention relates to a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.Type: ApplicationFiled: July 13, 2018Publication date: November 8, 2018Applicant: BIOM'UPInventors: Christian GAGNIEU, Patricia FOREST, Sylvain PICOT
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Patent number: 10046034Abstract: The invention relates to a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.Type: GrantFiled: March 21, 2017Date of Patent: August 14, 2018Assignee: BIOM'UPInventors: Christian Gagnieu, Patricia Forest, Sylvain Picot
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Patent number: 10004825Abstract: The invention relates to novel collagen materials and, specifically, collagen membranes, tubes and threads. Said materials combine enhanced properties of resilience and strength. The invention also relates to a method for preparing collagen materials using acid fibrous collagen comprising coagulation and, optionally, cross-linking of the collagen in the presence of ammonia gas.Type: GrantFiled: September 21, 2015Date of Patent: June 26, 2018Assignee: BIOM'UPInventors: Christian Gagnieu, Patricia Forest, Sylvain Picot
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Publication number: 20170189499Abstract: The invention relates to a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.Type: ApplicationFiled: March 21, 2017Publication date: July 6, 2017Applicant: BIOM'UPInventors: Christian GAGNIEU, Patricia FOREST, Sylvain PICOT
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Patent number: 9662374Abstract: The invention relates to a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.Type: GrantFiled: February 19, 2016Date of Patent: May 30, 2017Assignee: BIOM'UPInventors: Christian Gagnieu, Patricia Forest, Sylvain Picot
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Patent number: 9555185Abstract: A biomedical haemostatic powder dispenser (1) by which individual doses of powdered medication that are stored in respective chambers of a rotatable carousel (22) are fluidized for delivery to a targeted treatment site (e.g., a wound in order to stop bleeding). In particular, a squeeze handle (7) is activated (i.e., depressed) so as to cause a blast of gas under pressure to be applied from a gas reservoir (30) to a particular one of the powder-filled chambers of the medication carousel so that a single measured dose of medication is entrained and delivered to the patient. At the same time that the squeeze handle is activated, the medication carousel is rotated so that a different powder-filled chamber is moved within a fluid path between the gas reservoir and an outlet nozzle tube (10) of the dispenser and a kit for dispensing a powder.Type: GrantFiled: April 26, 2012Date of Patent: January 31, 2017Assignee: BIOM'UPInventors: Clark Foster, David Mishelevich, Eric Warner, Aaron Gifford
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Patent number: 9468708Abstract: The present invention relates to a composite matrix that includes a reinforcing textile portion having two surfaces coated over at least 90% of the respective surface areas thereof, by means of at least a first layer including at least one resorbable macro-molecule and having a collagen content of between 50 and 100 wt % relative to the total weight of the first layer; the invention also relates to a prosthesis including such a matrix and to a method for preparing said matrix.Type: GrantFiled: October 28, 2010Date of Patent: October 18, 2016Assignee: BIOM'UPInventors: Christian Gagnieu, Patricia Forest, Sylvain Picot
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Publication number: 20160166655Abstract: The invention relatesto a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.Type: ApplicationFiled: February 19, 2016Publication date: June 16, 2016Applicant: BIOM'UPInventors: Christian GAGNIEU, Patricia FOREST, Sylvain PICOT
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Patent number: 9283187Abstract: The invention relates to a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.Type: GrantFiled: April 26, 2012Date of Patent: March 15, 2016Assignee: BIOM'UPInventors: Christian Gagnieu, Patricia Forest, Sylvain Picot
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Publication number: 20160008509Abstract: The invention relates to novel collagen materials and, specifically, collagen membranes, tubes and threads. Said materials combine enhanced properties of resilience and strength. The invention also relates to a method for preparing collagen materials using acid fibrous collagen comprising coagulation and, optionally, cross-linking of the collagen in the presence of ammonia gas.Type: ApplicationFiled: September 21, 2015Publication date: January 14, 2016Applicant: BIOM'UPInventors: Christian GAGNIEU, Patricia FOREST, Sylvain PICOT
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Patent number: 9168326Abstract: The invention relates to novel collagen materials and, specifically, collagen membranes, tubes and threads. Said materials combine enhanced properties of resilience and strength. The invention also relates to a method for preparing collagen materials using acid fibrous collagen comprising coagulation and, optionally, cross-linking of the collagen in the presence of ammonia gas.Type: GrantFiled: April 28, 2010Date of Patent: October 27, 2015Assignee: BIOM'UPInventors: Christian Gagnieu, Patricia Forest, Sylvain Picot
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Publication number: 20140023714Abstract: The invention relates to a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.Type: ApplicationFiled: April 26, 2012Publication date: January 23, 2014Applicant: BIOM'UPInventors: Christian Gagnieu, Patricia Forest, Sylvain Picot
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Publication number: 20140018729Abstract: A biomedical haemostatic powder dispenser (1) by which individual doses of powdered medication that are stored in respective chambers of a rotatable carousel (22) are fluidized for delivery to a targeted treatment site (e.g., a wound in order to stop bleeding). In particular, a squeeze handle (7) is activated (i.e., depressed) so as to cause a blast of gas under pressure to be applied from a gas reservoir (30) to a particular one of the powder-filled chambers of the medication carousel so that a single measured does of medication is entrained and delivered to the patient. At the same time that the squeeze handle is activated, the medication carousel is rotated so that a different powder-filled chamber is moved within a fluid path between the gas reservoir and an outlet nozzle tube (10) of the dispenser and a kit for dispensing a powder.Type: ApplicationFiled: April 26, 2012Publication date: January 16, 2014Applicant: BIOM'UPInventors: Clark Foster, David Mishelevich, Eric Warner, Aaron Gifford
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Publication number: 20120253473Abstract: The present invention relates to a composite matrix that includes a reinforcing textile portion having two surfaces coated over at least 90% of the respective surface areas thereof, by means of at least a first layer including at least one resorbable macro-molecule and having a collagen content of between 50 and 100 wt % relative to the total weight of the first layer; the invention also relates to a prosthesis including such a matrix and to a method for preparing said matrix.Type: ApplicationFiled: October 28, 2010Publication date: October 4, 2012Applicant: BIOM'UPInventors: Christian Gagnieu, Patricia Forest, Sylvain Picot
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Patent number: D703707Type: GrantFiled: December 16, 2011Date of Patent: April 29, 2014Assignee: BIOM'UPInventors: Clark Foster, Aaron Gifford, David Mishelevich, Eric Warner, Sylvain Picot, Patricia Forest