Patents Assigned to BIOMAC PRIVATINSTITUT FUR MEDIZINISHE UND ZAHMEDIZ FORSCHUNG, ENTWICKLUNG UND DIAGNOSTIK GMBH
  • Substances and Pharmaceutical Compositions for the Inhibition of Glyoxalases and Their Use Against Bacteria
    Publication number: 20100204161
    Abstract: The present invention pertains to substances of the formula (I) wherein X is O or S; and R1-R4 are defined in the claims as inhibitors of glyoxalase I and/or II, pharmaceutical compositions comprising one or more compounds according to formula (I) and the use of one or more compounds according to formula (I) for the treatment of diseases associated with increased glycolytic metabolism. In one embodiment, the disease is a bacterial infection.
    Type: Application
    Filed: April 13, 2006
    Publication date: August 12, 2010
    Applicant: BIOMAC PRIVATINSTITUT FUR MEDIZINISHE UND ZAHMEDIZ FORSCHUNG, ENTWICKLUNG UND DIAGNOSTIK GMBH
    Inventors: Klaus Huse, Gerd Birkenmeier, Monika Birkenmeier