Patents Assigned to BIOMARIN PHARMACEUTICAL
  • TARGETED THERAPEUTIC PROTEINS
    Publication number: 20140056867
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: June 18, 2013
    Publication date: February 27, 2014
    Applicant: BIOMARIN PHARMACEUTICAL
    Inventors: Jonathan LeBowitz, Stephen M. Beverley