Abstract: The present invention is a holding case for an instrumented intra-oral appliance containing recorded data, which charges the intra-oral appliance while not in use and transmits recorded data to storage for review and analysis. The transferred data may be subjected to downloading, validation, storage, analysis, measuring, database fusion (with for example data from other devices), data output, and data recording. Output may be further transferred to a computer, processor, phone, tablet computer, or other hardware for review by a user or technical, research, medical, or other oversight personnel. The holding case can also send data to the appliance including firmware or other onboard operating instructions. The holding case can include additional features such as custom dentition of the user, UV light, or a visual user interface.

Abstract: An instrumented intra-oral appliance that has been designed computationally to optimize the location and coupling of sensors to optimize data integrity while maximizing comfort for the wearer. The 3D anatomical geometry can be collected directly with an intra-oral scanner or indirectly through an impression and scan of a dental stone model. A generalized design can be created to fit a target audience by obtaining 3D anatomical geometries of the target populations and performing a statistical shape analysis. Once the generalized design of the electronics is created, a unique design can be generated for each individual by locating the electronics such that they collect the best quality data possible. The individual designs can also be generated that maximize comfort for the wearer by minimizing size and volume, avoiding areas that could be painful, and ensuring proper retention of the device. Although not required, the device could be 3D printed to convert the computational design directly to an appliance.