Patents Assigned to Biomedica Foscama Industria Chimico-Farmaceutica S.p.A.
  • 8-(1-aminocycloalkyl)-1,3-dialkylxanthine derivatives, preparation process and antidepressant, nootropic and psychostimulant composition thereoff
    Patent number: 5378844
    Abstract: There are described 8-(1-aminocycloalkyl)-1,3-dialckylxantaine, their derivatives and their salts with adenosine antagonist activity. A process for the preparation of said compounds and pharmaceutical compositions containing them as antidepressant, nootropic and psychostimolant drugs are also described.
    Type: Grant
    Filed: January 22, 1993
    Date of Patent: January 3, 1995
    Assignee: Biomedica Foscama Industria Chimico-Farmaceutica S.p.A.
    Inventors: Mario Brufani, Romolo Scuri, Stefano Ceccarelli, Patrizia DeVellis, Patrizia Giannetti, Agnese Paesano, Zanarella Sergio
  • 2,3-dihydro-5-oxy-4,6,7-trimethylbenzofurans 2-(RS)-substituted, useful as antioxidizing pharmaceutical products having mucoregulating and anti-ischemic properties
    Patent number: 5114966
    Abstract: The herein-described invention concerns new 2,3-dihydro-5-oxy-4,6,7-trimethylbenzofuranes 2-(RS)-substituted, the synthesis procedure and the relative therapeutic use as antioxidizing and radical-scavenging pharmaceuticals with mucoregulation and anti-ischemic properties.
    Type: Grant
    Filed: August 6, 1990
    Date of Patent: May 19, 1992
    Assignee: Biomedica Foscama Industria Chimico-Farmaceutica S.p.A.
    Inventors: Romolo Scuri, Mario Brufani, Stefano Ceccarelli, Patrizia De Vellis, Patrizia Giannetti, Agnese Paesano, Sergio Zanarcella
  • Production of (RS)-2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl) acetic acid and related compounds
    Patent number: 5041568
    Abstract: The present invention relates to (RS)-2-(2,3-dihydro-5-hydroxy-4-,6-trimethylbenozfuranyl) acetic acids and 2-(2,3-dihydro-5-acyloxy-4-,6,7-trimethylbenzofuranyl) acetic acids and esters thereof, the process for producing them and their relevant therapeutical use as mucoregulators and antio-ischemic agents.
    Type: Grant
    Filed: September 17, 1990
    Date of Patent: August 20, 1991
    Assignee: Biomedica Foscama Industria Chimico-Farmaceutica S.p.A.
    Inventors: Mario Brufani, Stefano Ceccarelli, Patrizia Giannetti, Agnese Paesano, Romolo Scuri, Sergio Zanarella
  • Use of fructose-1,6-diphosphate in botany as germination and plant growth promoter
    Patent number: 5039330
    Abstract: The invention concerns the use of fructose-1,6-diphosphate in botany for the formulations of compositions suited for the stimulation of the germination of dormant seeds and of the growth of stem tissues of growing plants.
    Type: Grant
    Filed: March 6, 1990
    Date of Patent: August 13, 1991
    Assignee: Biomedica Foscama Industria Chimico-Farmaceutica S.p.A.
    Inventors: Guillermo M. Bisso, Franco Gitti
  • (RS)-2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl) acetic acids and 2-(2,3-dihydro-5-acyloxy-4,6,7-trimethylbenzofuranyl) acetic acids and esters thereof, useful as mucoregulator and anti-ischemic drugs
    Patent number: 4999350
    Abstract: The present invention relates to (RS)-2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl) acetic acids and 2-(2,3-dihydro-5-acyloxy-4,6,7-trimethylbenzofuranyl) acetic acids and esters thereof, the process for producing them and their relevant therapeutical use as mucoregulators and antiischemic agents.
    Type: Grant
    Filed: April 13, 1989
    Date of Patent: March 12, 1991
    Assignee: Biomedica Foscama Industria Chimico-Farmaceutica S.p.A.
    Inventors: Mario Brufani, Stefano Ceccarelli, Patrizia Giannetti, Agnese Paesano, Romolo Scuri, Sergio Zanarella
  • Use of fructose-1,6-diphosphate in the treatment of acute alcoholic intoxication and chronic ethylism, and related pharmaceutical compositions
    Patent number: 4870057
    Abstract: The present invention relates to the therapeutical use of a pharmaceutical composition of fructose 1,6-diphosphate (FDP) (sodium salt) which, intravenously administered, treats somatic and psychic manifestations caused by alcoholic intoxication.
    Type: Grant
    Filed: June 20, 1988
    Date of Patent: September 26, 1989
    Assignee: Biomedica Foscama Industria Chimico-Farmaceutica S.p.A.
    Inventors: Marco Chiapparelli, Ugo Cavicchia
  • Process for the preparation of fructose 1,6 diphosphate acid
    Patent number: 4575549
    Abstract: The process according to the invention provides, for the purification of FDPH.sub.4 -containing solutions, for a double chromatography combined with the molecular filtration.There are thus obtained concentrated and highly pure solutions containing fructose 1,6 diphosphate acid, which are perfectly suitable to be employed for the preparation of FDP and its salts.
    Type: Grant
    Filed: December 18, 1984
    Date of Patent: March 11, 1986
    Assignee: Biomedica Foscama Industria Chimico-Farmaceutica S.p.A.
    Inventors: Massimo Diana, Guglielmo M. Bisso
  • Method for producing fructose-1,6-diphosphoric acid
    Patent number: 4530902
    Abstract: A ferric salt of the fructose-1,6-diphosphate is disclosed, which can be precipitated quantitatively from FDP-containing mixtures and has the formula (FDP).sub.3 Fe.sub.4. For preparing such salt, a ferric salt and an alkali are added to a fermentation broth which contains FDP, whereafter the precipitate is thoroughly water washed to remove the alkali metal salt and the washed solids are dried or frozen. The ferric salt has many advantages over the calcium salt used heretofore and no organic solvents are any more required.
    Type: Grant
    Filed: September 28, 1979
    Date of Patent: July 23, 1985
    Assignee: Biomedica Foscama Industria Chimico Farmaceutica S.p.A.
    Inventors: Giulio C. Perri, Tommaso Bianco, Beniamino Piccirilli
  • Fructose-1,6-diphosphate preparation having protective action of erythrocyte membrane in patients undergoing extracorporeal circulation
    Patent number: 4448771
    Abstract: A preparation of fructose-1,6-diphosphate sodium salt made of a 10% solution in apyrogenic bidistilled water, characterized by protective activity of erythrocyte membrane.
    Type: Grant
    Filed: March 9, 1981
    Date of Patent: May 15, 1984
    Assignee: Biomedica Foscama Industria Chimico-Farmaceutica S.p.A.
    Inventors: Luciano Cattani, Renato Costrini