Patents Assigned to Biomedical International R+D GmbH
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Patent number: 12085574Abstract: Disclosed is a method for diagnosing allergy in a human or animal patient, wherein the level of species-specific lipocalin, especially lipocalin 2 in a human patient, is measured in a sample of said patient and wherein a lowered level of said lipocalin compared to the level of said lipocalin in the corresponding sample of a human or animal that has no allergy, is indicative of an allergy, as well as a kit for performing this method, and a kit for quality control of allergen molecules or extracts used for immunotherapy of allergy by determining its siderophore-iron ligand load and thus immunomodulatory potency. Further, lipocalin proteins for use in treatment or prevention of allergies are provided, preferably complexed with siderophore-iron ligands.Type: GrantFiled: January 13, 2021Date of Patent: September 10, 2024Assignee: BIOMEDICAL INTERNATIONAL R+D GMBHInventors: Franziska Roth-Walter, Erika Jensen-Jarolim, Cristina Gomez-Casado, Araceli Diaz Perales, Luis Fernandez Pacios, Josef Singer
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Publication number: 20210208164Abstract: Disclosed is a method for diagnosing allergy in a human or animal patient, wherein the level of species-specific lipocalin, especially lipocalin 2 in a human patient, is measured in a sample of said patient and wherein a lowered level of said lipocalin compared to the level of said lipocalin in the corresponding sample of a human or animal that has no allergy, is indicative of an allergy, as well as a kit for performing this method, and a kit for quality control of allergen molecules or extracts used for immunotherapy of allergy by determining its siderophore-iron ligand load and thus immunomodulatory potency. Further, lipocalin proteins for use in treatment or prevention of allergies are provided, preferably complexed with siderophore-iron ligands.Type: ApplicationFiled: January 13, 2021Publication date: July 8, 2021Applicant: BIOMEDICAL INTERNATIONAL R+D GMBHInventors: Franziska ROTH-WALTER, Erika JENSEN-JAROLIM, Cristina GOMEZ-CASADO, Araceli DIAZ PERALES, Luis FERNANDEZ PACIOS, Josef SINGER
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Patent number: 10914744Abstract: Disclosed is a method for diagnosing allergy in a human or animal patient, wherein the level of species-specific lipocalin, especially lipocalin 2 in a human patient, is measured in a sample of said patient and wherein a lowered level of said lipocalin compared to the level of said lipocalin in the corresponding sample of a human or animal that has no allergy, is indicative of an allergy, as well as a kit for performing this method, and a kit for quality control of allergen molecules or extracts used for immunotherapy of allergy by determining its siderophore-iron ligand load and thus immunomodulatory potency. Further, lipocalin proteins for use in treatment or prevention of allergies are provided, preferably complexed with siderophore-iron ligands.Type: GrantFiled: January 7, 2015Date of Patent: February 9, 2021Assignee: BIOMEDICAL INTERNATIONAL R+D GMBHInventors: Franziska Roth-Walter, Erika Jensen-Jarolim, Cristina Gomez-Casado, Araceli Diaz Perales, Luis Fernandez Pacios, Josef Singer
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Publication number: 20160334418Abstract: Disclosed is a method for diagnosing allergy in a human or animal patient, wherein the level of species-specific lipocalin, especially lipocalin 2 in a human patient, is measured in a sample of said patient and wherein a lowered level of said lipocalin compared to the level of said lipocalin in the corresponding sample of a human or animal that has no allergy, is indicative of an allergy, as well as a kit for performing this method, and a kit for quality control of allergen molecules or extracts used for immunotherapy of allergy by determining its siderophore-iron ligand load and thus immunomodulatory potency. Further, lipocalin proteins for use in treatment or prevention of allergies are provided, preferably complexed with siderophore-iron ligands.Type: ApplicationFiled: January 7, 2015Publication date: November 17, 2016Applicant: BIOMEDICAL INTERNATIONAL R+D GMBHInventors: Franziska ROTH-WALTER, Erika JENSEN-JAROLIM, Cristina GOMEZ-CASADO, Araceli DIAZ PERALES, Luis FERNANDEZ PACIOS, Josef SINGER
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Patent number: 9282725Abstract: A method for an observational screening method or a drug screening method, includes the steps of providing an enclosure for at least one animal with outer sidewalls, preferably 4 outer sidewalls; providing temperature sensing device for sensing a body temperature of at least one animal and/or activity measurement device for measuring at least one parameter related to physical activity of at least one animal; sensing a body temperature of at least one animal and/or measuring at least one parameter related to physical activity of at least one animal; providing data processing device; and processing data related to body temperature and/or to the parameter related to physical activity.Type: GrantFiled: March 11, 2014Date of Patent: March 15, 2016Assignee: Biomedical International R + D GmbHInventors: Erika Jensen-Jarolim, Ingo Flaschberger
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Publication number: 20140251228Abstract: A method for an observational screening method or a drug screening method, includes the steps of providing an enclosure for at least one animal with outer sidewalls, preferably 4 outer sidewalls; providing temperature sensing device for sensing a body temperature of at least one animal and/or activity measurement device for measuring at least one parameter related to physical activity of at least one animal; sensing a body temperature of at least one animal and/or measuring at least one parameter related to physical activity of at least one animal; providing data processing device; and processing data related to body temperature and/or to the parameter related to physical activity.Type: ApplicationFiled: March 11, 2014Publication date: September 11, 2014Applicant: Biomedical International R+D GmbHInventors: Erika JENSEN-JAROLIM, Ingo FLASCHBERGER