Patents Assigned to BIOMEDICAL RESEARCH FOUNDATION OF THE ACADEMY OF ATHENS
  • Bladder cancer biomarker proteins
    Patent number: 11536724
    Abstract: The invention relates to a collection of signature peptides representing at least 10 proteins for use in cancer diagnosis and/or prognosis, to an artificial protein comprising signature peptides representing at least 10 proteins and to a nucleic acid construct encoding for such an artificial protein. The invention further relates to a collection of at least 10 proteins for use in cancer diagnosis and/or prognosis. Additionally, the invention relates to a method for cancer diagnosis and/or prognosis comprising the step of analyzing at least 10 proteins in a urine sample of a subject. Finally, the invention relates to an immunoassay product comprising antibodies for detecting at least 10 proteins.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: December 27, 2022
    Assignees: POLYQUANT GMBH, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, BIOMEDICAL RESEARCH FOUNDATION OF THE ACADEMY OF ATHENS, LUXEMBOURG INSTITUTE OF HEALTH, INSTITUT CURIE, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS, FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III, CNIO
    Inventors: Jerome Garin, Christophe Masselon, Antonia Vlahou, Manousos Makrydakis, Ieronimos Zoidakis, Bruno Domon, Elodie Duriez, Aurelie Kamoun, Francois Radvanyi, Yves Allory, Nuria Malats Riera, Mirari Marquez Cid, Magali Court
  • Compounds for use in treating or preventing cancerous diseases
    Patent number: 10287294
    Abstract: The invention relates to new compounds of formula (I) that are useful in medicine, specifically in treating or preventing cancerous diseases in a mammal, to pharmaceutical compositions comprising such compounds, optionally together with other pharmaceutically active compounds, or to pharmaceutical formulations comprising such compounds or pharmaceutical compositions. The invention further relates to methods of making these compounds.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: May 14, 2019
    Assignee: BIOMEDICAL RESEARCH FOUNDATION OF THE ACADEMY OF ATHENS
    Inventors: Dimitris Stellas, Constantin Tamvakopoulos, Apostolos Klinakis, Argiris Efstratiadis, Zoe Cournia
  • Lipid assemblies comprising anionic lysolipids and use thereof
    Patent number: 9730893
    Abstract: The present invention relates to lipid assemblies, compositions, and liposomal delivery systems comprising single chain anionic lipids, and the use thereof in diagnosis and therapy. It involves the use of anionic lysolipids for modifying the surface charge of a cationic lipid composition consisting at least one type of cationic lipid, optionally in combination with one or more neutral lipids and/or one or more anionic lipids.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: August 15, 2017
    Assignee: BIOMEDICAL RESEARCH FOUNDATION OF THE ACADEMY OF ATHENS
    Inventors: Evgenios Siepis, Evangelos Andreakos