Abstract: Disclosed herein is a process for promoting the integration of a biocompatible device or implant into a tissue of a subject. The process comprises covalently bonding to the surface of the device or implant a compound of the formula I R-Q-X??I wherein R is cyclo-(Arg-Gly-Asp-Z), and wherein Q, X and Z are as defined herein.
Type:
Grant
Filed:
June 28, 2002
Date of Patent:
February 7, 2006
Assignee:
Biomet Deutchland GmbH
Inventors:
Jörg Meyer, Alfred Jonczyk, Berthold Nies, Horst Kessler, Dirk Finsinger, Martin Kantlehner