Patents Assigned to Bioneer Corporation
  • Patent number: 11175300
    Abstract: A biological sample processing apparatus, including: a pipette block with which a plurality of pipettes for sucking or discharging a biological sample in a multi-well plate in which wells are arranged in a matrix shape along row and column directions are detachably coupled; a pipette block forward and backward transfer unit configured to move the pipette block along a forward and backward direction along a process direction; a pipette block top and bottom transfer unit configured to move the pipette block along a vertical direction; a magnetic field applying unit disposed below the multi-well plate for applying a magnetic field to a well of the multi-well plate; and a heating unit disposed below the multi-well plate so as to be spaced apart from the magnetic field applying unit, for heating a well of the multi-well plate.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: November 16, 2021
    Assignee: BIONEER CORPORATION
    Inventors: Han Oh Park, Yang Won Lee, Jin Il Lee, Jung Do Kim, Dae Jin Jang, Jong Kab Kim
  • Patent number: 11123361
    Abstract: The present invention relates to a double-stranded oligo RNA structure comprising double-stranded miRNA, and a composition for preventing or treating cancer, containing the same. More specifically, the present invention relates to an anti-cancer pharmaceutical composition, containing: a double-stranded oligo RNA structure comprising miR-3670, miR-4477a and miR-8078, and characterized by a method for effectively inhibiting cancer cell proliferation or inducing cancer cell apoptosis; and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: September 21, 2021
    Assignee: BIONEER CORPORATION
    Inventors: Taewoo Lee, Sanghyung Shim, Ungsik Yu, Han-Oh Park
  • Patent number: 11087965
    Abstract: A sample plate for MALDI mass spectrometry, according to the present invention, enables separately positioning, by means of a plastic insulation plate, metal wiring and metal dots onto which an analyte sample is to be loaded, and electrically connecting same by means of a via or a metal portion, and thus the energy transferred into the plate when radiating a laser beam on the target (metal dots) may be reduced compared to a sample plate using a base metal, and thus laser energy may be concentrated on the target, and an effect may be achieved whereby heat loss is minimized.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: August 10, 2021
    Assignee: Bioneer Corporation
    Inventors: Taeman Kim, Jong Rok Ahn, Dohoon Kim, Han-Oh Park
  • Publication number: 20210233759
    Abstract: An ion guide for transferring ions to a mass analyzer is disclosed. The ion guide is characterized in that a plurality of DC rings and a plurality of RF multi-pole rings with a plurality of electrodes are arranged alternatingly along a central axis between an inlet into which the ions move and an outlet for transferring the ions. The inner diameter of the DC rings is kept constant and the inner diameter of the RF multi-pole rings gradually decreases in a direction from the inlet to the outlet.
    Type: Application
    Filed: June 4, 2019
    Publication date: July 29, 2021
    Applicant: BIONEER CORPORATION
    Inventors: Taeman KIM, Han-Oh PARK
  • Patent number: 11045808
    Abstract: The present invention relates to a micro chamber plate, and more particularly, to a micro chamber plate having micro chamber holes formed using a flowable film. Thus, samples can be injected into the micro chamber holes in a smoother manner compared to when samples are injected using a vacuum and/or centrifugal force. In addition, bubbles and excess samples in the micro chamber holes can be efficiently discharged, making it possible to perform reaction and analysis in a more accurate and efficient manner.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: June 29, 2021
    Assignee: BIONEER CORPORATION
    Inventors: Gu-Young Song, Han Oh Park, Won-Seok Jang, Jung A Bae
  • Publication number: 20210078008
    Abstract: The present invention relates to a device which is easy to use and in which real-time reaction product detection through nucleic acid extraction from a biospecimen, a PCR reaction, and scanning of excitation light of various wavelengths and fluorescence corresponding thereto can be automated, and thus various tests can be carried out in a single operation, and in particular, accurate results can be obtained in a short amount of time.
    Type: Application
    Filed: December 11, 2018
    Publication date: March 18, 2021
    Applicant: BIONEER CORPORATION
    Inventors: Han Oh PARK, Jong Kab KIM, Yang Won LEE, Sang Ryoung PARK, Hye Jin JANG
  • Publication number: 20210053059
    Abstract: The present invention relates to the structure of an analysis plate applied to a high-speed polymerase chain reaction (PCR), and to a PCR analysis plate used for implementing an analysis of a real-time PCR, a real-time nested PCR and a post-PCR lateral flow hybridization reaction. The present invention is provided with: a check valve for enabling the maintaining of positive pressure when an elastic film expands into a convex form by having a solution pushed therein by the positive pressure; a lateral flow analysis module for analyzing a post-PCR follow-up PCR or lateral flow; and a shut-off valve enabling the controlling of the movement of the solution after each reaction ends.
    Type: Application
    Filed: March 22, 2019
    Publication date: February 25, 2021
    Applicant: BIONEER CORPORATION
    Inventors: Han Oh PARK, Jong Kab KIM, Yang Won LEE, Sang Ryoung PARK
  • Patent number: 10844198
    Abstract: The present invention relates to an epoxy paste composition including silver-coated copper nanowires having a core-shell structure, and a conductive film including the same.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: November 24, 2020
    Assignee: BIONEER CORPORATION
    Inventors: Han Oh Park, Jae Ha Kim, Jun Pyo Kim, Jieun Kim
  • Publication number: 20200256767
    Abstract: A bio sample collection device including: a housing; a cap part detachably fastened to the housing, and including a bio sample collector for collecting a bio sample; and a bio sample processing liquid storage unit storing bio sample processing liquid, the bio sample processing liquid storage unit being formed to be broken when the cap part is combined with the housing after bio sample is collected so that the bio sample processing liquid is mixed with the bio sample.
    Type: Application
    Filed: October 24, 2017
    Publication date: August 13, 2020
    Applicant: BIONEER CORPORATION
    Inventors: Han Oh PARK, Jung Do KIM
  • Patent number: 10724031
    Abstract: The present invention relates to a method for preparing highly active silica magnetic nanoparticles, highly active silica magnetic nanoparticles prepared by the method, and a method of isolating nucleic acid using the highly active silica magnetic nanoparticles. The highly active silica magnetic nanoparticles prepared according to the present invention contain magnetic nanoparticles completely coated with silica, can be used as a reagent for isolating biomaterials, particularly, nucleic acids, and can isolate and purify nucleic acid in a high yield.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: July 28, 2020
    Assignee: BIONEER CORPORATION
    Inventors: Han Oh Park, Jae Ha Kim, Jong Gwang Park
  • Patent number: 10612026
    Abstract: The present invention relates to a pharmaceutical composition for treatment of cancer, which comprises, as an active ingredient, one or more miRNAs selected from the group consisting of miR-3670, miR-8078, and miR-4477a. The pharmaceutical composition for treatment of cancer according to the present invention exhibits excellent effects of inhibiting cancer cell proliferation and inducing cancer cell apoptosis. Thus, the pharmaceutical composition of the present invention can be effectively used as an anticancer therapeutic agent.
    Type: Grant
    Filed: March 31, 2019
    Date of Patent: April 7, 2020
    Assignee: BIONEER CORPORATION
    Inventors: Taewoo Lee, Sanghyung Shim, Ungsik Yu, Han Oh Park
  • Patent number: 10465184
    Abstract: The present invention relates to a method for preparing highly active silica magnetic nanoparticles, highly active silica magnetic nanoparticles prepared by the method, and a method of isolating nucleic acid using the highly active silica magnetic nanoparticles. The highly active silica magnetic nanoparticles prepared according to the present invention contain magnetic nanoparticles completely coated with silica, can be used as a reagent for isolating biomaterials, particularly, nucleic acids, and can isolate and purify nucleic acid in a high yield.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: November 5, 2019
    Assignee: BIONEER CORPORATION
    Inventors: Han Oh Park, Jae Ha Kim, Jong Gwang Park
  • Patent number: 10441957
    Abstract: The present invention relates to a magnetic particle separating device, and a method of separating and purifying nucleic acid or protein using the same. The device comprises: induction magnets (100); an induction magnet fixing part (200) having induction magnet fixing holes (210) for fixing the induction magnets (100); and a body (300) in which entry holes (310) are formed into which tubes (T) are inserted. Thus, the application and removal of a magnetic field to and from the body is made very convenient, so that the device can be very advantageously used in the separation and purification of nucleic acid or protein.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: October 15, 2019
    Assignee: BIONEER CORPORATION
    Inventors: Han Oh Park, Jong Kab Kim
  • Publication number: 20190227091
    Abstract: A biological sample processing apparatus, including: a pipette block with which a plurality of pipettes for sucking or discharging a biological sample in a multi-well plate in which wells are arranged in a matrix shape along row and column directions are detachably coupled; a pipette block forward and backward transfer unit configured to move the pipette block along a forward and backward direction along a process direction; a pipette block top and bottom transfer unit configured to move the pipette block along a vertical direction; a magnetic field applying unit disposed below the multi-well plate for applying a magnetic field to a well of the multi-well plate; and a heating unit disposed below the multi-well plate so as to be spaced apart from the magnetic field applying unit, for heating a well of the multi-well plate.
    Type: Application
    Filed: September 28, 2017
    Publication date: July 25, 2019
    Applicant: BIONEER CORPORATION
    Inventors: Han Oh PARK, Yang Won LEE, Jin IL LEE, Jung Do KIM, Dae Jin JANG, Jong Kab KIM
  • Patent number: 10351849
    Abstract: The present invention relates to a pharmaceutical composition for treatment of cancer, which comprises, as an active ingredient, one or more miRNAs selected from the group consisting of miR-3670, miR-8078, and miR-4477a. The pharmaceutical composition for treatment of cancer according to the present invention exhibits excellent effects of inhibiting cancer cell proliferation and inducing cancer cell apoptosis. Thus, the pharmaceutical composition of the present invention can be effectively used as an anticancer therapeutic agent.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: July 16, 2019
    Assignee: BIONEER CORPORATION
    Inventors: Taewoo Lee, Sanghyung Shim, Ungsik Yu, Han Oh Park
  • Patent number: 10287542
    Abstract: An automated cell-free protein production system comprises: a protein expression reaction unit comprising a reaction vessel that includes a plurality of dialysis tubes, each including a dialysis membrane and being open at its top; a reaction temperature control unit configured to heat or cool the reaction vessel; a pipette array comprising a plurality of pipettes and configured to suck or discharge solutions using the pipettes; a pipette array moving unit configured to move the pipette array in an upward and downward direction, a forward and backward direction or a left and right direction so as to move solutions; a protein purification unit including a magnetic field application device; and a multi-well plate mounting unit having mounted therein a multi-well plate kit configured to supply solutions that are used for protein production.
    Type: Grant
    Filed: November 29, 2013
    Date of Patent: May 14, 2019
    Assignee: BIONEER CORPORATION
    Inventors: Han Oh Park, Jong Kab Kim, Ji Won Han, You Sang Cho, Min Jung Kim, Ha Neul Kim, Yang Won Lee, Nam Il Kim
  • Patent number: 10249404
    Abstract: A ceramic paste composition including carbon nanotubes or a carbon nanotube-metal composite and a silicone adhesive, wherein the silicone adhesive includes 0.1 to 10 wt % of a silanol group, and has a mole ratio of a phenyl group to a methyl group of 0.3 to 2.5. The ceramic paste composition has low sheet resistance, through which an excellent heat generating property, and shielding, absorbing and conducting properties may be implemented in one or more embodiments. Further, though the ceramic paste composition has a very high heat generating temperature of 400° C., as compared with general paste based on carbon nanotubes, the physical properties thereof may be maintained stably. In addition, the ceramic paste may be widely used in various fields including heat generating products such as those for keeping warmth or heating, and products for electromagnetic wave shielding and absorption, electrodes, electronic circuits, antennas, and the like.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: April 2, 2019
    Assignee: BIONEER CORPORATION
    Inventors: Han Oh Park, Jae Ha Kim, Jun Pyo Kim
  • Publication number: 20190076843
    Abstract: Provided is a low heat capacity composite for a thermal cycler. The low heat capacity composite of the present invention is a low heat capacity composite for a thermal cycler capable of overcoming difficulty in manufacture and reproducibility due to uniqueness of the existing PCR thermal cycler only. The low heat capacity composite of the present invention can reduce the cost of raw material and retain excellent heat property due to the improvement in low heat capacity and physical and mechanical properties, thereby remarkably shortening PCR reaction time and saving energy when used as a thermal block for a thermal cycler.
    Type: Application
    Filed: November 12, 2018
    Publication date: March 14, 2019
    Applicant: BIONEER CORPORATION
    Inventors: Han Oh PARK, Jae Ha KIM
  • Patent number: 10208309
    Abstract: The present invention relates to a novel siRNA, and a high-efficiency double-stranded oligo RNA structure containing the same, and a nanoparticle containing the high-efficiency double-stranded oligo RNA structure. The double-stranded oligo RNA structure has a structure in which a hydrophilic material and a hydrophobic material are conjugated to both ends of a double-stranded oligo RNA (siRNA) via a simple covalent bond or linker-mediated covalent bond in order to be efficiently delivered into cells, and may be converted into a nanoparticle form in an aqueous solution by hydrophobic interactions of double-stranded oligo RNA structures. It is preferable that the siRNA contained in the double-stranded oligo RNA structure is an siRNA specific for fibrosis or respiratory disease-related gene, particularly, amphiregulin or stratifin.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: February 19, 2019
    Assignee: BIONEER CORPORATION
    Inventors: Jeiwook Chae, Pyoung Oh Yoon, Boram Han, Mi Na Kim, Youngho Ko, Han Oh Park
  • Patent number: RE48652
    Abstract: The present invention relates to a lactic acid bacterium isolated from human mother's milk, more precisely a Lactobacillus gasseri BNR17 strain that is isolated from Korean mother's milk and has excellent probiotic activity including acid resistance, bile acid resistance and antimicrobial activity and weight gaining inhibitory effect as well. Again, the Lactobacillus gasseri BNR17 of the present invention has excellent acid resistance, bile acid resistance, enteric absorption activity and antimicrobial activity against pathogenic microorganisms, in addition to the weight gaining inhibitory effect by synthesizing indigestible polysaccharides from monosaccharides included in food taken and releasing the synthesized polysaccharides out of the body.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: July 20, 2021
    Assignee: BIONEER CORPORATION
    Inventors: Ji Hee Kang, Byeung Il You, Sung Il Yun, Han Oh Park