Patents Assigned to Bioneer Corporation
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Publication number: 20240053374Abstract: The invention relates to an adapter for mounting a conductive pipette, a sample tube opening/closing device, and an automatic sample analysis system and, more specifically, to an adapter for mounting a conductive pipette, a sample tube opening/closing device, and an automatic sample analysis system, in which dispensing of a liquid sample and extraction, amplification and testing of nucleic acids are integrally carried out. The sample tube opening/closing device includes: a housing that forms an inner space isolated from the outside and includes a door for carrying in/out a multi-well plate for biological samples, including a plurality of sample tubes in which biological samples are accommodated; and a sample tube opening/closing part that is installed in the inner space to be spaced apart from the multi-well plate for biological samples and automatically opens and closes the sample tubes.Type: ApplicationFiled: December 7, 2021Publication date: February 15, 2024Applicant: BIONEER CORPORATIONInventors: Han Oh PARK, Hanee PARK, Jong Kab KIM, Dae Seong IM, Eun Yeong KWON
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Patent number: 11879876Abstract: A heater integrated gas chromatography (GC) column device according to the present invention is capable of precisely and uniformly controlling a temperature by having a high thermal conductivity, and raising and lowering a temperature at a high speed by having a low thermal mass, such that a measuring time is significantly decreased. The GC column is in contact with a bobbin with a homogeneous temperature distribution, and thus a temperature is homogeneously distributed in each GC column. Further, the heater integrated GC column device according to the present invention has the above-described effects and may have a smaller size.Type: GrantFiled: October 24, 2019Date of Patent: January 23, 2024Assignee: BIONEER CORPORATIONInventors: Han-Oh Park, Taeman Kim, Jong Rok Ahn, Jae-Ha Kim
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Publication number: 20230372945Abstract: The present invention relates to a nucleic acid amplification test apparatus, and an automatic sample analysis system having same and, more particularly, to a nucleic acid amplification test apparatus in which separation and purification, dispensation, amplification, and testing of samples are performed integrally, and an automatic sample analysis system having same.Type: ApplicationFiled: October 5, 2021Publication date: November 23, 2023Applicant: BIONEER CORPORATIONInventors: Han Oh PARK, Hanee PARK, JIN IL LEE, Jong Kab KIM, Eun Yeong KWON
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Patent number: 11820984Abstract: The present invention relates to a double-helix oligonucleotide construct comprising a double-stranded miRNA and a composition for preventing or treating cancer comprising the same. More particularly, the present invention relates to a double-helix oligonucleotide construct comprising miR-544a characterized by a method that effectively inhibits the proliferation of cancer cells or induces a voluntary death of cancer cells, and an anticancer composition comprising the construct.Type: GrantFiled: January 29, 2019Date of Patent: November 21, 2023Assignee: BIONEER CORPORATIONInventors: Taewoo Lee, Jiwon Ryu, Eun Ji Im
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Patent number: 11545349Abstract: The present invention relates to a matrix-assisted laser desorption ionization mass spectrometry method and, specifically, a mass spectrometry method according to the present invention comprises the steps of: acquiring a mass spectrum of an analyte by performing matrix-assisted laser desorption ionization of the analyte, wherein a detection spectrum, which is the mass spectrum of the analyte, is acquired using each of two or more matrixes different from one another; and removing, from each detection spectrum, a peak of a corresponding matrix to obtain a matrix-removed spectrum, and then acquiring a corrected mass spectrum of the analyte on the basis of a matrix-removed spectrum for each of different matrixes.Type: GrantFiled: October 30, 2017Date of Patent: January 3, 2023Assignee: BIONEER CORPORATIONInventors: Taeman Kim, Do Hoon Kim, Jong Rok Ahn, Han-Oh Park
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Patent number: 11543330Abstract: A bio sample collection device including: a housing; a cap part detachably fastened to the housing, and including a bio sample collector for collecting a bio sample; and a bio sample processing liquid storage unit storing bio sample processing liquid, the bio sample processing liquid storage unit being formed to be broken when the cap part is combined with the housing after bio sample is collected so that the bio sample processing liquid is mixed with the bio sample.Type: GrantFiled: October 24, 2017Date of Patent: January 3, 2023Assignee: BIONEER CORPORATIONInventors: Han Oh Park, Jung Do Kim
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Patent number: 11175300Abstract: A biological sample processing apparatus, including: a pipette block with which a plurality of pipettes for sucking or discharging a biological sample in a multi-well plate in which wells are arranged in a matrix shape along row and column directions are detachably coupled; a pipette block forward and backward transfer unit configured to move the pipette block along a forward and backward direction along a process direction; a pipette block top and bottom transfer unit configured to move the pipette block along a vertical direction; a magnetic field applying unit disposed below the multi-well plate for applying a magnetic field to a well of the multi-well plate; and a heating unit disposed below the multi-well plate so as to be spaced apart from the magnetic field applying unit, for heating a well of the multi-well plate.Type: GrantFiled: September 28, 2017Date of Patent: November 16, 2021Assignee: BIONEER CORPORATIONInventors: Han Oh Park, Yang Won Lee, Jin Il Lee, Jung Do Kim, Dae Jin Jang, Jong Kab Kim
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Patent number: 11123361Abstract: The present invention relates to a double-stranded oligo RNA structure comprising double-stranded miRNA, and a composition for preventing or treating cancer, containing the same. More specifically, the present invention relates to an anti-cancer pharmaceutical composition, containing: a double-stranded oligo RNA structure comprising miR-3670, miR-4477a and miR-8078, and characterized by a method for effectively inhibiting cancer cell proliferation or inducing cancer cell apoptosis; and a pharmaceutically acceptable carrier.Type: GrantFiled: August 24, 2017Date of Patent: September 21, 2021Assignee: BIONEER CORPORATIONInventors: Taewoo Lee, Sanghyung Shim, Ungsik Yu, Han-Oh Park
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Patent number: 11087965Abstract: A sample plate for MALDI mass spectrometry, according to the present invention, enables separately positioning, by means of a plastic insulation plate, metal wiring and metal dots onto which an analyte sample is to be loaded, and electrically connecting same by means of a via or a metal portion, and thus the energy transferred into the plate when radiating a laser beam on the target (metal dots) may be reduced compared to a sample plate using a base metal, and thus laser energy may be concentrated on the target, and an effect may be achieved whereby heat loss is minimized.Type: GrantFiled: February 14, 2018Date of Patent: August 10, 2021Assignee: Bioneer CorporationInventors: Taeman Kim, Jong Rok Ahn, Dohoon Kim, Han-Oh Park
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Publication number: 20210233759Abstract: An ion guide for transferring ions to a mass analyzer is disclosed. The ion guide is characterized in that a plurality of DC rings and a plurality of RF multi-pole rings with a plurality of electrodes are arranged alternatingly along a central axis between an inlet into which the ions move and an outlet for transferring the ions. The inner diameter of the DC rings is kept constant and the inner diameter of the RF multi-pole rings gradually decreases in a direction from the inlet to the outlet.Type: ApplicationFiled: June 4, 2019Publication date: July 29, 2021Applicant: BIONEER CORPORATIONInventors: Taeman KIM, Han-Oh PARK
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Patent number: 11045808Abstract: The present invention relates to a micro chamber plate, and more particularly, to a micro chamber plate having micro chamber holes formed using a flowable film. Thus, samples can be injected into the micro chamber holes in a smoother manner compared to when samples are injected using a vacuum and/or centrifugal force. In addition, bubbles and excess samples in the micro chamber holes can be efficiently discharged, making it possible to perform reaction and analysis in a more accurate and efficient manner.Type: GrantFiled: November 12, 2014Date of Patent: June 29, 2021Assignee: BIONEER CORPORATIONInventors: Gu-Young Song, Han Oh Park, Won-Seok Jang, Jung A Bae
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Publication number: 20210078008Abstract: The present invention relates to a device which is easy to use and in which real-time reaction product detection through nucleic acid extraction from a biospecimen, a PCR reaction, and scanning of excitation light of various wavelengths and fluorescence corresponding thereto can be automated, and thus various tests can be carried out in a single operation, and in particular, accurate results can be obtained in a short amount of time.Type: ApplicationFiled: December 11, 2018Publication date: March 18, 2021Applicant: BIONEER CORPORATIONInventors: Han Oh PARK, Jong Kab KIM, Yang Won LEE, Sang Ryoung PARK, Hye Jin JANG
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Publication number: 20210053059Abstract: The present invention relates to the structure of an analysis plate applied to a high-speed polymerase chain reaction (PCR), and to a PCR analysis plate used for implementing an analysis of a real-time PCR, a real-time nested PCR and a post-PCR lateral flow hybridization reaction. The present invention is provided with: a check valve for enabling the maintaining of positive pressure when an elastic film expands into a convex form by having a solution pushed therein by the positive pressure; a lateral flow analysis module for analyzing a post-PCR follow-up PCR or lateral flow; and a shut-off valve enabling the controlling of the movement of the solution after each reaction ends.Type: ApplicationFiled: March 22, 2019Publication date: February 25, 2021Applicant: BIONEER CORPORATIONInventors: Han Oh PARK, Jong Kab KIM, Yang Won LEE, Sang Ryoung PARK
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Patent number: 10844198Abstract: The present invention relates to an epoxy paste composition including silver-coated copper nanowires having a core-shell structure, and a conductive film including the same.Type: GrantFiled: October 31, 2017Date of Patent: November 24, 2020Assignee: BIONEER CORPORATIONInventors: Han Oh Park, Jae Ha Kim, Jun Pyo Kim, Jieun Kim
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Publication number: 20200256767Abstract: A bio sample collection device including: a housing; a cap part detachably fastened to the housing, and including a bio sample collector for collecting a bio sample; and a bio sample processing liquid storage unit storing bio sample processing liquid, the bio sample processing liquid storage unit being formed to be broken when the cap part is combined with the housing after bio sample is collected so that the bio sample processing liquid is mixed with the bio sample.Type: ApplicationFiled: October 24, 2017Publication date: August 13, 2020Applicant: BIONEER CORPORATIONInventors: Han Oh PARK, Jung Do KIM
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Highly active silica magnetic nanoparticles for purifying biomaterial and preparation method thereof
Patent number: 10724031Abstract: The present invention relates to a method for preparing highly active silica magnetic nanoparticles, highly active silica magnetic nanoparticles prepared by the method, and a method of isolating nucleic acid using the highly active silica magnetic nanoparticles. The highly active silica magnetic nanoparticles prepared according to the present invention contain magnetic nanoparticles completely coated with silica, can be used as a reagent for isolating biomaterials, particularly, nucleic acids, and can isolate and purify nucleic acid in a high yield.Type: GrantFiled: September 27, 2019Date of Patent: July 28, 2020Assignee: BIONEER CORPORATIONInventors: Han Oh Park, Jae Ha Kim, Jong Gwang Park -
Patent number: 10612026Abstract: The present invention relates to a pharmaceutical composition for treatment of cancer, which comprises, as an active ingredient, one or more miRNAs selected from the group consisting of miR-3670, miR-8078, and miR-4477a. The pharmaceutical composition for treatment of cancer according to the present invention exhibits excellent effects of inhibiting cancer cell proliferation and inducing cancer cell apoptosis. Thus, the pharmaceutical composition of the present invention can be effectively used as an anticancer therapeutic agent.Type: GrantFiled: March 31, 2019Date of Patent: April 7, 2020Assignee: BIONEER CORPORATIONInventors: Taewoo Lee, Sanghyung Shim, Ungsik Yu, Han Oh Park
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Highly active silica magnetic nanoparticles for purifying biomaterial and preparation method thereof
Patent number: 10465184Abstract: The present invention relates to a method for preparing highly active silica magnetic nanoparticles, highly active silica magnetic nanoparticles prepared by the method, and a method of isolating nucleic acid using the highly active silica magnetic nanoparticles. The highly active silica magnetic nanoparticles prepared according to the present invention contain magnetic nanoparticles completely coated with silica, can be used as a reagent for isolating biomaterials, particularly, nucleic acids, and can isolate and purify nucleic acid in a high yield.Type: GrantFiled: September 15, 2015Date of Patent: November 5, 2019Assignee: BIONEER CORPORATIONInventors: Han Oh Park, Jae Ha Kim, Jong Gwang Park -
Patent number: 10441957Abstract: The present invention relates to a magnetic particle separating device, and a method of separating and purifying nucleic acid or protein using the same. The device comprises: induction magnets (100); an induction magnet fixing part (200) having induction magnet fixing holes (210) for fixing the induction magnets (100); and a body (300) in which entry holes (310) are formed into which tubes (T) are inserted. Thus, the application and removal of a magnetic field to and from the body is made very convenient, so that the device can be very advantageously used in the separation and purification of nucleic acid or protein.Type: GrantFiled: December 5, 2014Date of Patent: October 15, 2019Assignee: BIONEER CORPORATIONInventors: Han Oh Park, Jong Kab Kim
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Patent number: RE48652Abstract: The present invention relates to a lactic acid bacterium isolated from human mother's milk, more precisely a Lactobacillus gasseri BNR17 strain that is isolated from Korean mother's milk and has excellent probiotic activity including acid resistance, bile acid resistance and antimicrobial activity and weight gaining inhibitory effect as well. Again, the Lactobacillus gasseri BNR17 of the present invention has excellent acid resistance, bile acid resistance, enteric absorption activity and antimicrobial activity against pathogenic microorganisms, in addition to the weight gaining inhibitory effect by synthesizing indigestible polysaccharides from monosaccharides included in food taken and releasing the synthesized polysaccharides out of the body.Type: GrantFiled: May 14, 2018Date of Patent: July 20, 2021Assignee: BIONEER CORPORATIONInventors: Ji Hee Kang, Byeung Il You, Sung Il Yun, Han Oh Park