Abstract: A method of implanting a stent whereby the risk of restenosis is reduced, the method including the step of implanting into a patient susceptible to post-implant restenosis a stent coated with a therapeutically effective amount of a compound for reducing the onset or severity of restenosis, the compound containing a high density, negatively charged domain of at least three vicinally oriented phosphorus-containing radicals.
Abstract: The invention relates to an improved construction of a coated surgical stent with a compound containing a high density, negatively charged domain of at least three vicinally oriented phosphorous-containing radicals, such device being defined as an object used for example to hold open blood vessels dilated by angioplasty, particularly coronary blood vessels, iliac aretrias and the alike and which device are utilized to widen blood vessels or other orifices in the body and which compound is preventing restenosis.