Patents Assigned to Bionicrie Life Sciences, Inc.
  • Conformation-activity relationship of apoptosis-inducing phosphodiester oligonucleotides
    Patent number: 7200531
    Abstract: The present invention facilitates in silico evaluation of molecules for biological activity by providing a computer-based method to predict whether oligonucleotides may possess biological activity and the efficacy of the biological activity based on the three-dimensional structure and charge characteristics of the oligonucleotides. Biological activities include, but are not limited to, cellular proliferation, induction of cell cycle arrest and apoptosis.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: April 3, 2007
    Assignee: Bionicrie Life Sciences, Inc.
    Inventors: Nigel C. Phillips, Mario C. Filion, Zdenek Richard Holan, Stéphanie Reader