Patents Assigned to BioNime Corporation
  • Patent number: 11950902
    Abstract: The present invention provides a micro biosensor for reducing a measurement interference when measuring a target analyte in the biofluid, including: a substrate; a first working electrode configured on the surface, and including a first sensing section; a second working electrode configured on the surface, and including a second sensing section which is configured adjacent to at least one side of the first sensing section; and a chemical reagent covered on at least a portion of the first sensing section for reacting with the target analyte to produce a resultant. When the first working electrode is driven by a first working voltage, the first sensing section measures a physiological signal with respect to the target analyte. When the second working electrode is driven by a second working voltage, the second conductive material can directly consume the interferant so as to continuously reduce the measurement inference of the physiological signal.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: April 9, 2024
    Assignee: Bionime Corporation
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Heng-Chia Chang, Chi-Hao Chen, Pi-Hsuan Chen
  • Patent number: 11925789
    Abstract: An elastic physiological patch includes a patch assembly and an implant assembly. The patch assembly includes an electronic device, and a soft patch body defining a chamber for receiving the electronic device. The implant assembly is mountable to the electronic device and includes an implant which is capable of being driven to partially pass through the patch body and which is adapted to be implanted in the skin of a subject. The implant and the patch body cooperatively seal the chamber.
    Type: Grant
    Filed: January 14, 2022
    Date of Patent: March 12, 2024
    Assignee: Bionime Corporation
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Jia-Nan Shen, Kuan-Lin Chang
  • Patent number: 11925461
    Abstract: The present invention discloses a holder carrying thereon a sensor to measure a physiological signal of an analyte in a biological fluid, wherein the sensor has a signal detection end and a signal output end, and the holder includes an implantation hole being a channel for implanting the sensor and containing a part of the sensor, a fixing indentation containing the sensor, a filler disposed in the fixing indentation to retain the sensor in the holder, and a blocking element disposed between the implantation hole and the fixing indentation to hold the sensor in the holder and restrict the filler in the fixing indentation.
    Type: Grant
    Filed: October 18, 2022
    Date of Patent: March 12, 2024
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11896804
    Abstract: An insertion device includes an upper casing, an insertion module and a lower casing. The insertion module is disposed in the upper casing, and includes a main body assembly, an insertion seat, a first elastic member, a retraction seat and a second elastic member. When the upper casing is depressed, the insertion seat is driven by the first elastic member to perform an automatic-insertion operation, such that limiting structure between the insertion seat and the retraction seat collapses upon the collapse of another limiting structure between the insertion seat and the main body assembly, and that the retraction seat is driven by the second elastic member to perform an automatic-retraction operation.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: February 13, 2024
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Chen-Hao Lee, Kuan-Lin Chang
  • Patent number: 11894120
    Abstract: A moisture-proof assembly for keeping away from a moisture comprises a housing, a cover, a physiological signal transmitter, a charging device and a desiccant. The housing has an opening. The cover is detachably disposed on the housing, configured to seal the opening, and forms an accommodating space together with the housing. The physiological signal transmitter is disposed in the accommodating space for measuring and transmitting a physiological signal. The charging device is combined with the physiological signal transmitter and disposed together or the charging device and the physiological signal sensor are separate disposed in the accommodating space. The desiccant is disposed in the accommodating space to prevent the physiological signal transmitter from moisture, wherein when the physiological signal transmitter is in need of being charged, the charging device is taken out of the accommodating space, and connected to an external power source to charge the physiological signal transmitter.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: February 6, 2024
    Assignee: BIONIME CORPORATION
    Inventors: Chieh-Hsing Chen, Chun-Mu Huang
  • Patent number: 11852643
    Abstract: A physiological signal monitoring device is adapted for monitoring a physiological signal of a biofluid, and includes: a biosensor strip that has at least one signal output end adapted for outputting the physiological signal; a strip reciprocating module that includes a strip seat for receiving the biosensor strip, a guide seat mounted to the strip seat, and a rotating plate mounted rotatably to the strip seat for triggering reciprocating movement of the biosensor strip and the guide seat relative to the strip seat; and a contact module that includes an electronic module, and at least one extending piece connected electrically with the at least one signal output end to transmit the physiological signal to the electronic module.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: December 26, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Li-Kang Huang, Chun-Mu Huang
  • Patent number: 11786154
    Abstract: A biosensing device includes a sensor module and an electric signal transducer. The sensor module includes a biosensor adapted for measuring a biosignal of a host, and a fixed seat including a conducting member that is electrically connected to the biosensor. The electric signal transducer is for receiving and sending the biosignal measured by the biosensor, is coupled to the sensor module, and includes an electric signal unit electrically connected to the conducting member, and a battery connected to the electric signal unit. The electric signal unit has two electrical contacts that cooperatively define a switch. The battery provides power supply to the biosensor when the electric signal transducer is coupled to the sensor module.
    Type: Grant
    Filed: June 27, 2022
    Date of Patent: October 17, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11766193
    Abstract: A biosensor for measuring a physiological signal representative of a physiological parameter associated with an analyte is described. The biosensor includes a working electrode and a counter electrode. The counter electrode including a silver and a silver halide having an initial amount, wherein the initial amount is determined by the following steps of defining a required consumption range of the silver halide during at least one of the measurement periods performed by the biosensor; and determining the initial amount based on a sum of an upper limit of the required consumption range and a buffer amount, so that a required replenishment amount range of the silver halide during the replenishment period is controlled to be sufficient to maintain an amount of the silver halide within a safe storage range.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: September 26, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11737686
    Abstract: The present invention discloses a holder carrying thereon a sensor to measure a physiological signal of an analyte in a biological fluid, wherein the sensor has a signal detection end and a signal output end, and the holder includes an implantation hole being a channel for implanting the sensor and containing a part of the sensor, a containing indentation containing the signal output end, a fixing indentation fixing thereto the sensor and communicating with the containing indentation, a waterproof seal disposed above the implantation hole, an elastic divider disposed in the implantation hole to separate the implantation hole and covering all over a cross-sectional area of the implantation hole, and a blocking element disposed between the implantation hole and the fixing indentation to hold the sensor.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: August 29, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11737689
    Abstract: A physiological signal monitoring device includes a sensing member and a transmitter connected to the sensing member and including a circuit board that has electrical contacts, and a connecting port, which includes a socket communicated to the circuit board and a plurality of steel balls. The sensing member is removably inserted into the socket. The steel balls are electrically connected to the electrical contacts and the sensing member for enabling electric connection therebetween. Each of the steel balls is frictionally rotated by the sensing member during insertion of the sensing member into the socket and removal of the sensing member from the socket.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: August 29, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11717192
    Abstract: The present invention discloses a holder carrying thereon a sensor to measure a physiological signal of an analyte in a biological fluid, wherein the sensor has a signal detection end and a signal output end, and the holder includes an implantation hole being a channel for implanting the sensor and containing a part of the sensor, a waterproof seal disposed above the implantation hole, and an elastic divider disposed in the implantation hole to separate the implantation hole and covering all over a cross-sectional area of the implantation hole.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: August 8, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11717198
    Abstract: A physiological signal monitoring device includes a sensing member and a transmitter connected to the sensing member and including a circuit board that has electrical contacts, and a connecting port, which includes a socket communicated to the circuit board and a plurality of conducting springs. The sensing member is removably inserted into the socket. The conducting springs are electrically connected to the electrical contacts and the sensing member for enabling electric connection therebetween. Each of the conducting springs is frictionally moved by the sensing member during insertion of the sensing member into the socket and removal of the sensing member from the socket.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: August 8, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11707213
    Abstract: A physiological signal monitoring device includes a sensing member and a transmitter connected to the sensing member and including a circuit board that has electrical contacts, and a connecting port, which includes a socket communicated to the circuit board and a plurality of conducting springs disposed at two opposite sides of the socket. The sensing member is removably inserted into the socket. The conducting springs are electrically connected to the electrical contacts and the sensing member for enabling electric connection therebetween. Each of the conducting springs is frictionally rotated by the sensing member during insertion of the sensing member into the socket and removal of the sensing member from the socket.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: July 25, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11678846
    Abstract: An insertion device includes a cover body, an insertion module. The insertion module is disposed in the cover body, and includes a main body, an insertion seat, a first elastic member, a retraction seat and a second elastic member. When the cover body is depressed, the insertion seat is driven by the first elastic member to perform an automatic-insertion operation and to collapse a limiting structure between the insertion seat and the cover body. A limiting structure between the insertion seat and the retraction seat collapses upon the collapse of the limiting structure between the insertion seat and the cover body, so that the retraction seat is driven by the second elastic member to perform an automatic-retraction operation.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: June 20, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Chen-Hao Lee, Kuan-Lin Chang
  • Patent number: 11665238
    Abstract: A method for data transmission between a sensor device and an electronic device includes: broadcasting, by the sensor device, a beacon dataset and a sensor dataset associated with the beacon dataset; in receipt of the beacon dataset, determining, by the electronic device, whether to receive the sensor dataset associated with the beacon dataset; and when it is determined to receive the sensor dataset associated with the beacon dataset, operating, by the electronic device, in a scan mode so as to receive the sensor dataset associated with the beacon dataset.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: May 30, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chih-Lung Yeh, Cheng-Wei Lu, Yung-Feng Lai, Guan-Yu Lu, Yuan-Chieh Lin
  • Patent number: 11633128
    Abstract: A method for assembling a physiological signal monitoring apparatus on a body surface of a living body is provided, wherein the physiological signal monitoring apparatus is used to measure a physiological signal and includes a sensor module and a transmitter. The method comprises steps of: (a) detaching the bottom cover from the housing to expose the sticker from the bottom opening; (b) while holding the housing, causing the adhesive pad to be attached to the body surface; (c) applying a pressing force on the housing to cause the sensor module to be detached from the implantation module and the signal sensing end to be implanted under the body surface; (d) removing the implanting device while leaving the sensor module on the body surface; and (e) placing the transmitter on the base so that the signal output end is electrically connected to the port.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: April 25, 2023
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen, Kuan-Lin Chang, Chen-Hao Lee
  • Patent number: 11517229
    Abstract: A biosensing device includes a sensor module and an electric signal transducer. The sensor module includes a biosensor adapted for measuring a biosignal of a host, and a fixed seat including a conducting member that is electrically connected to the biosensor. The electric signal transducer is for receiving and sending the biosignal measured by the biosensor, is coupled to the sensor module, and includes an electric signal unit electrically connected to the conducting member, and a battery connected to the electric signal unit. The electric signal unit has two electrical contacts that cooperatively define a switch. The battery provides power supply to the biosensor when the electric signal transducer is coupled to the sensor module.
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: December 6, 2022
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: 11521731
    Abstract: A charging device for a physiological signal transmitter is disclosed, wherein the physiological signal transmitter is to receive and externally transmit a physiological signal from a subcutaneous tissue of a living body, and has a first electrical connecting port. The charging device comprises a transmitter placing seat, a charging module and a locking module. The transmitter placing seat includes a bearing surface, and a first opening. The bearing surface disposes thereon the physiological signal transmitter; and the first opening aligns therewith the first electrical connecting port of the physiological signal transmitter. The charging module includes a second electrical connecting port, a third electrical connecting port and a circuit assembly. The second electrical connecting port is disposed in the first opening and moveable between a first position and a second position. The third electrical connecting port is for connecting thereto a power source.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: December 6, 2022
    Assignee: BIONIME CORPORATION
    Inventors: Chieh-Hsing Chen, Chun-Mu Huang
  • Patent number: 11506627
    Abstract: A method for prolonging a usage lifetime of a micro biosensor to measure a physiological signal associated with an analyte is provided. The micro biosensor includes a working electrode, a counter electrode including silver and a silver halide having an initial amount, and an auxiliary electrode. The method includes cyclic steps of: applying a measurement voltage to drive the working electrode to measure the physiological signal; stopping applying the measurement voltage; and whenever the physiological parameter is obtained, applying a replenishment voltage between the counter electrode and the auxiliary electrode to drive the counter electrode, thereby the silver halide of a replenishment amount being replenished to the counter electrode, wherein a guarding value of a sum of the replenishment amount and the initial amount subtracting a consumption amount is controlled within a range of the initial amount plus or minus a specific value.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: November 22, 2022
    Assignee: BIONIME CORPORATION
    Inventors: Chun-Mu Huang, Chieh-Hsing Chen
  • Patent number: D1009661
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: January 2, 2024
    Assignee: BIONIME CORPORATION
    Inventor: Hsueh-Chuan Chang