Patents Assigned to BIONOMICS INC.
  • Methods of blocking cancer stem cell growth
    Patent number: 10598653
    Abstract: Disclosed herein are antibodies against GPR49 and uses of such antibodies. The antibodies can be monoclonal, humanized, or fully human antibodies against GPR49, hybridomas or other cell lines expressing such antibodies, nucleic acids and vectors comprising nucleic acids encoding for such antibodies, and methods of blocking cancer stem cell growth with such antibodies.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: March 24, 2020
    Assignee: BIONOMICS INC.
    Inventors: Christopher L. Reyes, Peter Chu, Xiangyang Tan, Weixing Yang, Christilyn Graff
  • Humanized antibodies that bind LGR5
    Patent number: 10358500
    Abstract: Disclosed herein are humanized anti-LGR5 antibodies for the treatment of cancer. Antibodies disclosed herein may bind LGR5 without disrupting LGR5-RSPO1 binding or signaling, and may disrupt LGR5 signaling through Wnt that is independent of RSPO1. Also disclosed are heavy and light chain polypeptide sequences for the biding of LGR5, for example without disrupting LGR5-RSPO binding or signaling.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: July 23, 2019
    Assignee: BIONOMICS INC.
    Inventors: Christopher L. Reyes, Peter Chu, Kristen M. Smith, Lioudmila A. Campbell, Farbod Shojaei, John Thomas Norton
  • CANCER STEM CELLS EXPRESSING ABCG2
    Publication number: 20130244268
    Abstract: Cancer Stem Cell populations characterized by expression of ABCG2 and methods of isolating and using the same are disclosed.
    Type: Application
    Filed: March 1, 2013
    Publication date: September 19, 2013
    Applicant: BIONOMICS INC.
    Inventors: Peter Chu, Robert Peach