Patents Assigned to Biopatterns, S.R.O.
  • 2-SUBSTITUTED-6-BIARYLMETHYLAMINO-9-CYCLOPENTYL-9H-PURINE DERIVATIVES, USE THEREOF AS MEDICAMENTS, AND PHARMACEUTICAL COMPOSITIONS
    Publication number: 20150368248
    Abstract: This invention relates to novel 2-substituted-6-biarylmethylamino-9-cyclopentyl-9H-purine derivatives, showing activity as specific inhibitors of growth and angiogenesis of hepatocellular carcinoma. The invention further includes pharmaceutical compositions containing the 2-substituted-6-biarylmethylamino-9-cyclopentylpurines.
    Type: Application
    Filed: February 5, 2014
    Publication date: December 24, 2015
    Applicants: BIOPATTERNS S.R.O., UNIVERZITA PALACKEHO V OLOMOUCI
    Inventors: Tomas GUCKY, Radek JORDA, Marek ZATLOUKAL, Vladimir KRYSTOF, Lucie RAROVA, Eva REZNICKOVA, Wolfgang MIKULITS, Miroslav STRNAD
  • Substituted 6-(Benzylamino) Purine Riboside Derivatives, Use Thereof and Compositions Containing These Derivatives
    Publication number: 20140066394
    Abstract: A method of treatment using 2-substituted-6-(substituted benzylamino)purine riboside derivatives of the general formula I. These compounds possess antiapoptotic, anti-inflammatory and differentiating activities.
    Type: Application
    Filed: October 7, 2013
    Publication date: March 6, 2014
    Applicants: Biopatterns, S.R.O, Univerzita Palackeho V Olomouci
    Inventors: Lucie SZUCOVA, Vladimir KRYSTOF, Marek ZATLOUKAL, Karel DOLEZAL, Miroslav STRNAD, Lukas SPICHAL
  • Substituted 6-(2-hydroxybenzylamino)purine derivatives, their use as medicaments and compositions containing these derivatives
    Patent number: 8492391
    Abstract: The invention relates to substituted 6-(2-hydroxybenzylamino)purines of general formula I, to their activity as cyclin-dependent kinases 2, 5, 7 and 9 inhibitors and to their use as medicaments, particularly in the treatment of disorders involving cell proliferation or inflammation. The invention further includes pharmaceutical compositions containing the substituted 6-(2-hydroxybenzylamino)purines.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: July 23, 2013
    Assignees: Univerzita Palackeho V Olomouci, Biopatterns, S.R.O.
    Inventors: Marek Zatloukal, Vladimir Krystof, Libor Havlicek, Igor Popa, Karel Dolezal, Miroslav Strnad, Radek Jorda