Abstract: The present invention relates to a pharmaceutical composition containing broussochalcone A as an active ingredient for prevention or treatment of inflammatory bowel disease. The pharmaceutical composition containing broussochalcone A as an active ingredient for prevention or treatment of inflammatory bowel disease of the present invention suppresses inflammation to ameliorate symptoms of weight loss, reduction in bowel length, diarrhea, and hemafecia, which result from inflammatory bowel disease, and has no side effects occurring in an existing drug medicine, and thus can be effectively used in the treatment of inflammatory bowel disease.