Abstract: The invention relates to an injectable composition intended for tissue induction of the soft tissues by a system of immediate and prolonged progressive release. In particular, the invention relates to a composition comprising a gel of at least one first biodegradable polymer forming a first agent for filling soft tissues in an animal, and a suspension in this gel of microspheres with an average diameter between 5 and 50 micrometres, said microspheres comprising 50 to 90 wt. % of at least one biodegradable polysaccharide relative to the total weight of the microspheres, said microspheres inducing a second filling by tissue induction and containing at least one second biodegradable polymer forming at least one third filling of the soft tissues in an animal.
Abstract: The present invention relates to a hydrogel of chitosan carboxyalkylamide, characterised in that it has a pH value close to that of the skin, comprised between 6.5 and 7.2, and in that the chitosan carboxy-alkylamide is constituted by 40 to 90 mole % of D-glucosamine N-carboxyalkylamide units of formula (I) where n represents an integer ranging from 1 to 8, from 60 to 10 mole % of protonated D-glucosamine units, and from 5 to 15 mole % of N-acetyl-D-glucosamine units. The present invention also relates to a dehydration product of such a gel and the cosmetic and/or dermatological utilisation of the gel and the dehydration product.
Type:
Application
Filed:
July 1, 2008
Publication date:
July 22, 2010
Applicant:
Biopharmex Holding Limited
Inventors:
Elisabeth Laugier, Franck Gouchet, Jean-Pierre Perraud