Abstract: The present invention relates to recombinant expression vectors which express segments of deoxyribonucleic acid that encode recombinant HIV and HCV antigens. These recombinant expression vectors are transformed into host cells and used in a method to express large quantities of these antigens. The invention also provides compositions containing certain of the isolated antigens, diagnostic systems containing these antigens and methods of assaying body fluids to detect the presence of antibodies against the antigens of the invention.
Type:
Grant
Filed:
March 14, 2008
Date of Patent:
January 4, 2011
Assignees:
Bioprocess Pty Ltd., P. Hoffmann-La Roche, Ltd.
Inventors:
Suzanne Zebedee, Genevieve Inchauspe, Marc S. Nasoff, Alfred M Prince