Patents Assigned to Bioproject
  • Benzazole derivatives as histamine H4 receptor ligands
    Patent number: 8802664
    Abstract: The present patent application concerns new ligands of the H4-receptor of formula (I), their process of preparation and their therapeutic use.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: August 12, 2014
    Assignee: Bioproject
    Inventors: Isabelle Berrebi-Bertrand, Xavier Billot, Thierry Calmels, Marc Capet, Denis Danvy, Stephane Krief, Olivier Labeeuw, Jeanne-Marie Lecomte, Nicolas Levoin, Xavier Ligneau, Philippe Robert, Jean-Charles Schwartz
  • Combinations of an anti emetic agent and an enkephalinase inhibitor
    Patent number: 8222294
    Abstract: The present invention concerns combinations of an anti-emetic agent and an enkephalinase inhibitor for use in methods for treating diarrhea and/or gastroenteritis.
    Type: Grant
    Filed: February 14, 2005
    Date of Patent: July 17, 2012
    Assignee: Bioproject
    Inventors: Jean-Charles Schwartz, Jeanne-Marie Lecomte
  • Polymorphic forms of fasidotril, their methods of preparation and pharmaceutical compositions comprising them
    Patent number: 6767921
    Abstract: The subject of the present invention is the various polymorphic forms I, II, III, IV of benzyl (S,S)-2-(2-acetylsulphanylmethyl-3-benzo[1,3]dioxol-5-ylpropionyl-amino)propionate, hereinafter called Fasidotril, their methods of preparation and novel pharmaceutical compositions containing them.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: July 27, 2004
    Assignee: Bioproject
    Inventors: Marc Capet, Gérard Coquerel, Denis Danvy, Jeanne-Marie Lecomte, Marie-Noëlle Petit, Jean-Charles Schwartz
  • Histamine derivative, process for preparing it and its therapeutic use
    Patent number: 5034539
    Abstract: The present invention relates to .alpha.,.beta.-dimethylhistamine, of the rmula: ##STR1## in racemic form, or an optical isomer form or mixture of diastereoisomers and its acid addition salts. It may be prepared from an alkyl 2-amino 3-(1H-imidazol-4-yl)-carboxylate.
    Type: Grant
    Filed: September 29, 1989
    Date of Patent: July 23, 1991
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Bioproject
    Inventors: Jean-Michel Arrang, Monique Garbarg, Walter Schunack, Jean-Charles Schwartz, Ralph O. Lipp