Patents Assigned to BioQuest, Incorporated
  • Preparation and use of novel injectable RES avoiding inorganic particles for medical application
    Patent number: 5547682
    Abstract: Novel N-RES agents for use in vitro and in vivo medical and biological applications, such as, for example MRI and/or intravenous administration of pharmaceutical agents are described. The novel N-RES agents are prepared by coating inorganic core particles with a poly(acrylic acid)--poly(alkylene ether) graft copolymer. The resulting polymer-coated inorganic particle cores are useful as imaging agents, therapeutic agents or carriers having increased circulation time due to decrease uptake or recognition by the RES.
    Type: Grant
    Filed: July 20, 1994
    Date of Patent: August 20, 1996
    Assignee: BioQuest, Incorporated
    Inventors: Mark S. Chagnon, Stephen E. Burkle, Michelle J. Carter, Tracy J. Hamilton, John Havelick, Jr., Deborah A. Kaplan, Kristin L. Marzloff